523 research outputs found
Flow reversals in thermally driven turbulence
We analyze the reversals of the large scale flow in Rayleigh-B\'enard
convection both through particle image velocimetry flow visualization and
direct numerical simulations (DNS) of the underlying Boussinesq equations in a
(quasi) two-dimensional, rectangular geometry of aspect ratio 1. For medium
Prandtl number there is a diagonal large scale convection roll and two smaller
secondary rolls in the two remaining corners diagonally opposing each other.
These corner flow rolls play a crucial role for the large scale wind reversal:
They grow in kinetic energy and thus also in size thanks to plume detachments
from the boundary layers up to the time that they take over the main, large
scale diagonal flow, thus leading to reversal. Based on this mechanism we
identify a typical time scale for the reversals. We map out the Rayleigh number
vs Prandtl number phase space and find that the occurrence of reversals very
sensitively depends on these parameters.Comment: 4 pages, 4 figure
Testing the Bell Inequality at Experiments of High Energy Physics
Besides using the laser beam, it is very tempting to directly testify the
Bell inequality at high energy experiments where the spin correlation is
exactly what the original Bell inequality investigates. In this work, we follow
the proposal raised in literature and use the successive decays
to testify
the Bell inequality. Our goal is twofold, namely, we first make a Monte-Carlo
simulation of the processes based on the quantum field theory (QFT). Since the
underlying theory is QFT, it implies that we pre-admit the validity of quantum
picture. Even though the QFT is true, we need to find how big the database
should be, so that we can clearly show deviations of the correlation from the
Bell inequality determined by the local hidden variable theory. There have been
some critiques on the proposed method, so in the second part, we suggest some
improvements which may help to remedy the ambiguities indicated by the
critiques. It may be realized at an updated facility of high energy physics,
such as BES III.Comment: 16 pages, 5 figure
A New Method to Calculate Electromagnetic Impedance Matching Degree in One-Layer Microwave Absorbers
A delta-function method was proposed to quantitatively evaluate the
electromagnetic impedance matching degree. Measured electromagnetic parameters
of {\alpha}-Fe/Fe3B/Y2O3 nanocomposites are applied to calculate the matching
degree by the method. Compared with reflection loss and quarter-wave principle
theory, the method accurately reveals the intrinsic mechanism of microwave
transmission and reflection properties. A possible honeycomb structure with
promising high-performance microwave absorption according to the method is also
proposed.Comment: 13 pages, 3 figure
Topological structure of the many vortices solution in Jackiw-Pi model
We construct an M-solitons solutions in Jackiw-Pi model depends on 5M
parameters(two positions, one scale, one phase per solition and one charge of
each solution). By using \phi -mapping method, we discuss the topological
structure of the self-duality solution in Jackiw-Pi model in terms of gauge
potential decomposition. We set up relationship between Chern-Simons vortices
solution and topological number which is determined by Hopf indices and and
Brouwer degrees. We also give the quantization of flux in this case.Comment: 14 pages, 4 figure
An Updated Search of Steady TeV Ray Point Sources in Northern Hemisphere Using the Tibet Air Shower Array
Using the data taken from Tibet II High Density (HD) Array (1997
February-1999 September) and Tibet-III array (1999 November-2005 November), our
previous northern sky survey for TeV ray point sources has now been
updated by a factor of 2.8 improved statistics. From to
in declination (Dec) range, no new TeV ray point
sources with sufficiently high significance were identified while the
well-known Crab Nebula and Mrk421 remain to be the brightest TeV ray
sources within the field of view of the Tibet air shower array. Based on the
currently available data and at the 90% confidence level (C.L.), the flux upper
limits for different power law index assumption are re-derived, which are
approximately improved by 1.7 times as compared with our previous reported
limits.Comment: This paper has been accepted by hepn
Nonlocality of two-qubit and three-qubit Schmidt-Correlated states
We investigate the nonlocality of Schmidt-correlated (SC) states, and present
analytical expressions of the maximum violation value of Bell inequalities. It
is shown that the violation of Clauser-Horne-Shimony-Holt (CHSH) inequality is
necessary and sufficient for the nonlocality of two-qubit SC states, whereas
the violation of the Svetlichny inequality is only a sufficient condition for
the genuine nonlocality of three-qubit SC states. Furthermore, the relations
among the maximum violation values, concurrence and relative entropy
entanglement are discussed.Comment: 12 page
Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
<p>Abstract</p> <p>Background</p> <p>Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-induced neurological deficits; however, the signaling pathways are not apparent by which the upstream cellular events trigger innate immune and inflammatory responses that contribute to neurological impairments. Toll-like receptor 4 (TLR4) plays a role in inflammatory damage caused by brain disorders.</p> <p>Methods</p> <p>In this study, we investigate the role of TLR4 signaling in ICH-induced inflammation. In the ICH model, a significant upregulation of TLR4 expression in reactive microglia has been demonstrated using real-time RT-PCR. Activation of microglia was detected by immunohistochemistry, cytokines were measured by ELISA, MyD88, TRIF and NF-κB were measured by Western blot and EMSA, animal behavior was evaluated by animal behavioristics.</p> <p>Results</p> <p>Compared to WT mice, TLR4<sup>−/− </sup>mice had restrained ICH-induced brain damage showing in reduced cerebral edema and lower neurological deficit scores. Quantification of cytokines including IL-6, TNF-α and IL-1β and assessment of macrophage infiltration in perihematoma tissues from TLR4<sup>−/−</sup>, MyD88<sup>−/− </sup>and TRIF<sup>−/− </sup>mice showed attenuated inflammatory damage after ICH. TLR4<sup>−/− </sup>mice also exhibited reduced MyD88 and TRIF expression which was accompanied by decreased NF-κB activity. This suggests that after ICH both MyD88 and TRIF pathways might be involved in TLR4-mediated inflammatory injury possibly via NF-κB activation. Exogenous hemin administration significantly increased TLR4 expression and microglial activation in cultures and also exacerbated brain injury in WT mice but not in TLR4<sup>−/− </sup>mice. Anti-TLR4 antibody administration suppressed hemin-induced microglial activation in cultures and in the mice model of ICH.</p> <p>Conclusions</p> <p>Our findings suggest that heme potentiates microglial activation <it>via </it>TLR4, in turn inducing NF-κB activation <it>via </it>the MyD88/TRIF signaling pathway, and ultimately increasing cytokine expression and inflammatory injury in ICH. Targeting TLR4 signaling may be a promising therapeutic strategy for ICH.</p
Neurochemical Properties of the Synapses in the Pathways of Orofacial Nociceptive Reflexes
The brainstem premotor neurons of the facial nucleus (VII) and hypoglossal (XII) nucleus can integrate orofacial nociceptive input from the caudal spinal trigeminal nucleus (Vc) and coordinate orofacial nociceptive reflex (ONR) responses. However, the synaptoarchitectures of the ONR pathways are still unknown. In the current study, we examined the distribution of GABAergic premotor neurons in the brainstem local ONR pathways, their connections with the Vc projections joining the brainstem ONR pathways and the neurochemical properties of these connections. Retrograde tracer fluoro-gold (FG) was injected into the VII or XII, and anterograde tracer biotinylated dextran amine (BDA) was injected into the Vc. Immunofluorescence histochemical labeling for inhibitory/excitatory neurotransmitters combined with BDA/FG tracing showed that GABAergic premotor neurons were mainly distributed bilaterally in the ponto-medullary reticular formation with an ipsilateral dominance. Some GABAergic premotor neurons made close appositions to the BDA-labeled fibers coming from the Vc, and these appostions were mainly distributed in the parvicellular reticular formation (PCRt), dorsal medullary reticular formation (MdD), and supratrigeminal nucleus (Vsup). We further examined the synaptic relationships between the Vc projecting fibers and premotor neurons in the VII or XII under the confocal laser-scanning microscope and electron microscope, and found that the BDA-labeled axonal terminals that made asymmetric synapses on premotor neurons showed vesicular glutamate transporter 2 (VGluT2) like immunoreactivity. These results indicate that the GABAergic premotor neurons receive excitatory neurotransmission from the Vc and may contribute to modulating the generation of the tonic ONR
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