Information Systems Faculty Perceptions of Ethical Work Climate and Job Satisfaction

This study investigated the relationships among egoistic ethical work climate, benevolent ethical work climate, principled ethical work climate, and job satisfaction as perceived by IS faculty at public institutions of higher education in the Southeastern United States. They study relied on constructs from previous studies to measure ethical work climate and job satisfaction. Statistically significant findings were observed between egoistic ethical work climate, benevolent ethical work climate, principled ethical work climate, and job satisfaction. The development of benevolent or principled ethical work climates has a positive relationship with faculty job satisfaction. In contrast, there is a strong inverse correlation between egoistic ethical work climates and faculty’s perception of job satisfaction

Information Systems Faculty Perceptions of Ethical Work Climate and Job Satisfaction

The purpose of this work in progress is to provide an overview of the current research literature in the areas of ethical work climate and employee job satisfaction, and then present a model that will help guide future research on the relationship among egoistic ethical work climate, benevolent ethical work climate, and principled ethical work climate and job satisfaction as perceived by information systems faculty at institutions of higher education in the southeastern United States

Drug dosing during pregnancy—opportunities for physiologically based pharmacokinetic models

Drugs can have harmful effects on the embryo or the fetus at any point during pregnancy. Not all the damaging effects of intrauterine exposure to drugs are obvious at birth, some may only manifest later in life. Thus, drugs should be prescribed in pregnancy only if the expected benefit to the mother is thought to be greater than the risk to the fetus. Dosing of drugs during pregnancy is often empirically determined and based upon evidence from studies of non-pregnant subjects, which may lead to suboptimal dosing, particularly during the third trimester. This review collates examples of drugs with known recommendations for dose adjustment during pregnancy, in addition to providing an example of the potential use of PBPK models in dose adjustment recommendation during pregnancy within the context of drug-drug interactions. For many drugs, such as antidepressants and antiretroviral drugs, dose adjustment has been recommended based on pharmacokinetic studies demonstrating a reduction in drug concentrations. However, there is relatively limited (and sometimes inconsistent) information regarding the clinical impact of these pharmacokinetic changes during pregnancy and the effect of subsequent dose adjustments. Examples of using pregnancy PBPK models to predict feto-maternal drug exposures and their applications to facilitate and guide dose assessment throughout gestation are discussed

Classification of large acoustic datasets using machine learning and crowdsourcing : application to whale calls

A.M.v.B.B. acknowledges support from the Sea Mammal Research Unit at the University of St. Andrews (Professor Ian Boyd) and Woods Hole Oceanographic Institution for the Whale FM project. P.T. received funding from the Marine Alliance for Science and Technology for Scotland (MASTS).Vocal communication is a primary communication method of killer and pilot whales, and is used for transmitting a broad range of messages and information for short and long distance. The large variation in call types of these species makes it challenging to categorize them. In this study, sounds recorded by audio sensors carried by ten killer whales and eight pilot whales close to the coasts of Norway, Iceland, and the Bahamas were analyzed using computer methods and citizen scientists as part of the Whale FM project. Results show that the computer analysis automatically separated the killer whales into Icelandic and Norwegian whales, and the pilot whales were separated into Norwegian long-finned and Bahamas short-finned pilot whales, showing that at least some whales from these two locations have different acoustic repertoires that can be sensed by the computer analysis. The citizen science analysis was also able to separate the whales to locations by their sounds, but the separation was somewhat less accurate compared to the computer method.Publisher PDFPeer reviewe