1,713 research outputs found

    The Spectacular Radio-Near-IR-X-ray Jet of 3C 111: X-ray Emission Mechanism and Jet Kinematics

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    Relativistic jets are the most energetic manifestation of the active galactic nucleus (AGN) phenomenon. AGN jets are observed from the radio through gamma-rays and carry copious amounts of matter and energy from the sub-parsec central regions out to the kiloparsec and often megaparsec scale galaxy and cluster environs. While most spatially resolved jets are seen in the radio, an increasing number have been discovered to emit in the optical/near-IR and/or X-ray bands. Here we discuss a spectacular example of this class, the 3C 111 jet, housed in one of the nearest, double-lobed FR II radio galaxies known. We discuss new, deep Chandra and HST observations that reveal both near-IR and X-ray emission from several components of the 3C 111 jet, as well as both the northern and southern hotspots. Important differences are seen between the morphologies in the radio, X-ray and near-IR bands. The long (over 100 kpc on each side), straight nature of this jet makes it an excellent prototype for future, deep observations, as it is one of the longest such features seen in the radio, near-IR/optical and X-ray bands. Several independent lines of evidence, including the X-ray and broadband spectral shape as well as the implied velocity of the approaching hotspot, lead us to strongly disfavor the EC/CMB model and instead favor a two-component synchrotron model to explain the observed X-ray emission for several jet components. Future observations with NuSTAR, HST, and Chandra will allow us to further constrain the emission mechanisms.Comment: 12 pages, 9 figures, ApJ, in pres

    西村先生講話 第二回

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    Nexus file containing phased alleles from BDNF sequences of Sunda shelf Crocidura. This alignment was used to generate the gene trees in Figures S1 and S

    New development: Directly elected mayors in Italy: creating a strong leader doesn’t mean creating strong leadership

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    More than 20 years after their introduction, directly elected mayors are key players in Italian urban governance. This article explains the main effects of this reform on local government systems and provides lessons for other countries considering directly elected mayors

    Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.

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    BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease of right ventricular morphology, as well as in a rodent model of right ventricular hypertrophy (RVH).MethodsHomogenates of right ventricle (RV) explants from non-failing controls and children born with a SV were assayed for HDAC catalytic activity and HDAC isoform expression. Postnatal 1-day-old rat pups were placed in hypoxic conditions, and echocardiographic analysis, gene expression, HDAC catalytic activity, and isoform expression studies of the RV were performed.ResultsClass I, IIa, and IIb HDAC catalytic activity and protein expression were elevated in the hearts of children born with a SV. Hypoxic neonatal rats demonstrated RVH, abnormal gene expression, elevated class I and class IIb HDAC catalytic activity, and protein expression in the RV compared with those in the control.ConclusionsThese data suggest that myocardial HDAC adaptations occur in the SV heart and could represent a novel therapeutic target. Although further characterization of the hypoxic neonatal rat is needed, this animal model may be suitable for preclinical investigations of pediatric RV disease and could serve as a useful model for future mechanistic studies

    Parents, Schools and HSSR

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    As parents become more involved in the schools and as schools st rive to involve parents in meaningful ways and extend the work that is done in schools, educators should look at promising educational practices that can be reinforced in the home environment. One of these reinforcing, supportive activIties that are feasible for all parents and children, yet do not require instructional technology, is Sustained Silent Reading, which has been effectively utilized in schools

    Evaluation/Testing Procedures In Reading

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    This is the second in a series of four articles devoted to parents and reading. The first article described typical school reading programs and illustrated the key ingredients of each. This article treats the evaluation and testing procedures that schools use in the area of reading

    School-Based Reading Programs

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    There are three basic types of reading programs that your child is likely to encounter; they include the basal reading approach, the language experience approach and the individualized reading approach. The major components, strengths and weaknesses of each approach are presented in Figure 1 at the end of the article. The basal reader approach is used in the majority of elementary classrooms

    Technological Resources For Parents

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    This is the final article in the series devoted to parents and reading. The first article described typical school reading programs. The second article described different types, purposes and scores of reading tests. The third article focused upon parental involvement in reading and presented activities that could be used at home and school. This article will focus upon recent technological advances, such as television, VCRs and computers, and how parents can use these tools to help their children

    Parents: An Untapped Resource

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    This is the third in a series of four articles devoted to parents and reading. The first article described typical school reading programs. The second article described different types, purposes, and scores of reading tests. This article will focus upon parental involvement in reading and will examine research and activities that can be beneficial at home and at school
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