Chronic infection of domestic cats with feline morbillivirus, United States

Letter [No abstract available

Mammal species composition and habitat associations in a commercial forest and mixed-plantation landscape

Commercial forest plantations of fast-growing species have been established globally to meet increasing demands for timber, pulpwood, and other wood products. Industrial plantations may contribute to tropical forest conservation by reducing exploitation of primary and secondary natural forests. Whether such plantations can support critical elements of biodiversity, including provision of habitat and movement corridors for species of conservation concern, is an important question in Southeast Asia. Our objectives were to investigate relationships between habitat gradients and community attributes of medium-sized to large mammals in a mixed plantation mosaic in Bengkoka Peninsula, Sabah, East Malaysia. Data on mammals were collected using 59 remote camera stations deployed for a minimum of 21 days (24-hour sampling occasions) in three major land-use types: natural forest, Acacia plantations, and non-Acacia plantations (oil palm, rubber, young Eucalyptus pellita). We used sample-based rarefaction to evaluate variation in species richness with land use. We used generalized linear models and ordination analyses to evaluate whether variation in mammal detections and species composition was associated with habitat gradients. We recorded >22 mammal species over 1572 sampling occasions. Natural forest area was positively associated with mammal species richness and detections of threatened mammals. Overall detections of mammals increased with decreasing elevation, but decreased within, and close to, Acacia plantations. Detections of threatened mammals increased with greater proportions of natural forest and Acacia and increasing proximity to roads. Sample-based rarefaction indicated that species richness of mammals in Acacia and natural forest was considerably higher than observed. Both natural forest and Acacia plantations shared similar values for species richness and diversity, but non-Acacia plantations scored lower in both metrics. Mammal species composition differed among different types of land use. Smaller generalists used non-Acacia plantation forests. A variety of other mammals including some threatened species used natural forest, Acacia, or a combination of the two. Acacia plantations possess attributes supporting a diversity of mammal species, including those we defined as threatened based on IUCN criteria. However, this is likely a function of the habitat mosaic with natural forest in the study area and the mangrove forests on the fringes of the peninsula serving as refuges of mammal diversity. Retention and restoration of natural and mangrove forests may therefore enhance the conservation potential of industrial Acacia plantations. Additionally, controlled road access in conjunction with anti-poaching operations and strengthening public awareness are essential to reduce the threat of overexploitation

Sealant Effectiveness for Children Receiving a Combination of Preventive Methods in a Fluoridated Community: Two-Year Results

A series of preventive methods in combination have been used to reduce dental caries in children including dental health education, prophylaxes, pit and fissure sealants, topical application of fluoride and restorative care. Prophylaxes, sealant, and fluoride procedures are repeated every six months. Two-year results show reductions of occlusal caries increments of 74.3% for first graders and 77.1% for sixth graders. Sealant loss, as defined in this study, varied from 33% to 90% with the highest loss occurring in the newly erupted permanent molars during the first six months of the project. These high sealant loss rates are thought to be related to the age of the population which was designed to include children at the ages of peak eruption of permanent molar teeth (ages six and twelve). These teeth were often only minimally erupted and maintaining the dry field required for sealant retention was extremely difficult. However, in spite of these high rates of sealant loss, caries reduction on occlusal surfaces was highly significant in comparison to that of children who did not receive sealants.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68154/2/10.1177_00220345770560121801.pd

Search for jet extinction in the inclusive jet-pT spectrum from proton-proton collisions at s=8 TeV

Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published articles title, journal citation, and DOI.The first search at the LHC for the extinction of QCD jet production is presented, using data collected with the CMS detector corresponding to an integrated luminosity of 10.7  fb−1 of proton-proton collisions at a center-of-mass energy of 8 TeV. The extinction model studied in this analysis is motivated by the search for signatures of strong gravity at the TeV scale (terascale gravity) and assumes the existence of string couplings in the strong-coupling limit. In this limit, the string model predicts the suppression of all high-transverse-momentum standard model processes, including jet production, beyond a certain energy scale. To test this prediction, the measured transverse-momentum spectrum is compared to the theoretical prediction of the standard model. No significant deficit of events is found at high transverse momentum. A 95% confidence level lower limit of 3.3 TeV is set on the extinction mass scale

Novel feline viruses: Emerging significance of gammaherpesvirus and morbillivirus infections

Practical relevance: New technologies capable of sequencing the genetic material in any given biological sample, combined with computer-based algorithms for sequence assembly and analysis, have revolutionised infectious disease research. The rate at which novel viruses are being discovered now exceeds our understanding of their clinical relevance. Novel viruses may contribute to diseases that are major causes of feline morbidity and mortality, including cancer and chronic kidney disease. The identification of new viral pathogens raises the prospect of not only improved patient outcomes through specific treatment but even disease prevention through viral control measures. Clinical challenges: It can be difficult to determine the role of a novel virus in disease development. Disease may be an occasional outcome, often years after infection. A high prevalence of infection in the general population can make disease associations harder to identify and almost impossible to rule out. Host cofactors such as immune dysfunction, genetic background or coinfections may be required for manifestation of disease, and one virus species may be linked to a range of pathological sequelae. Establishing causality relies on evaluating accumulating evidence from multiple investigations, which is often hard to access by practitioners. Global importance: The worldwide distribution of gammaherpesvirus and morbillivirus infections in domestic cats underlines the potential of these viruses to negatively impact feline health and welfare globally. Evidence base: This review relies on grade la—III evidence

Mapping the evolutionary trajectories of morbilliviruses: What, where and whither

Morbilliviruses are pathogens of humans and other animals. Live attenuated morbillivirus vaccines have been used to end endemic transmission of measles virus (MV) in many parts of the developed world and to eradicate rinderpest virus. Entry is mediated by two different receptors which govern virus lymphotropism and epitheliotropism. Morbillivirus transmissibility is unparalleled and MV represents the most infectious human pathogen on earth. Their evolutionary origins remain obscure and their potential for adaption to new hosts is poorly understood. It has been suggested that MV could be eradicated. Therefore it is imperative to dissect barriers which restrict cross species infections. This is important as ecological studies identify novel morbilliviruses in a vast number of small mammals and carnivorous predators