AGE DIFFERENCES AND MACROECONOMIC EFFECTS ON FOOD STAMP PROGRAM PARTICIPATION

Low income populations are more severely affected by economic downturns than their high income counterparts because they are at high risk of unemployment and face reduced earnings in recessions. The use of food stamp benefits and other types of welfare are one mechanism that families can use to buffer the economic shock brought about by income losses due to unemployment during a recession. As a result, during unfavorable economic conditions, low income households disproportionately rely on public assistance including food stamps. What is less understood are the differential effects of macroeconomic conditions on the participation propensities of different population subgroups. Of particular importance are differential effects by age. Depending on their age, poor workers are likely to experience different patterns of unemployment so that their welfare participation patterns also differ. For example, once older workers lose their jobs, their probability of re-employment is lower than that of their younger counterparts. The reduced expectations of re-employment coupled with fewer opportunities to invest in re-training are discouraging to older unemployed persons, often implying that job losses for older workers are permanent, and eventually lead to long term reliance on welfare programs. In contrast, younger poor workers have comparatively higher chances of re-employment and exit from welfare. Whether the age differences in welfare participation will remain unchanged during economic recessions as well is still unanswered. Understanding variations in FSP participation propensities across age groups and their dependency on macroeconomic conditions is essential to predict future demand for food stamp benefits and, by extension, other welfare programs. The continuing growth in FSP demand may point to unexpectedly large fiscal burdens for future taxpayers. Moreover, understanding differential effects of macroeconomic conditions on participation propensities for different groups will allow policy makers to better identify and eventually reach genuine needy families. Therefore, this study aims to investigate FSP participation patterns with a special emphasis on the differential impact of macroeconomic factors across several demographic groups with a particular focus on age cohort effects. Specifically, transitions into and out of FSP will be explicitly addressed using longitudinal data from the Survey of Income and Program Participation (SIPP) 2004 panel. To measure the impact of economic conditions, we match SIPP data with economic measures such as the unemployment rate and wages at the state level available from the Bureau of Labor Statistics. Using the data, monthly movements on and off of FSP of individuals is followed and categorized into entry sample and continuation sample. A household not participating in FSP in one month, and thus being part of the entry sample, can choose between entering or not entering FSP in the subsequent month. Similarly, a household enrolled in one month (and thus part of the continuation sample) can choose between either continuing to stay on FSP or exiting FSP in the next month. This gives rise to two types of transition models. The first model, referred to as the entry model, tackles the decision between entry versus non-entry into FSP, conditional on non-participation in the previous months. The second model, referred to as continuation model, addresses the decision between exiting from versus continuing FSP, conditional upon participation in the preceding month. Two transition models are estimated using probit technique while controlling for individual specific effects. This study finds several important results. First, there are significant age differences in entry into and exit from the FSP. The propensity of entry into the FSP among younger people is higher than among older people while young cohorts are more prone to exiting FSP than the oldest cohort of retired or retirement-bound people. The implication for the elderly is that once receiving FSP benefits, they are very likely to continue the FSP. Their observed low FSP participation rates can thus primarily be attributed to FSP entry barriers. Second, rising unemployment boosts FSP entry propensities and lengthens FSP spells. Changes in wage levels, however, affect neither entry nor exit propensities. Third, the effect of unemployment on FSP continuation propensities varies by age. The youngest cohort responds to increasing unemployment by drastically prolonging their FSP spells whereas the older extend their FSP spells more gradually. For the oldest cohort, FSP exit probabilities are even found to rise in association with rising unemployment, a phenomenon that can be explained by retirement and special transfer programs for the elderly.Food Stamp Program, Age, Macroeconomy, Transition, Agricultural and Food Policy, Food Consumption/Nutrition/Food Safety, I38, J64,

Phylogeography of cliff-dwelling relicts with a highly narrow and disjunct distribution in the western Mediterranean

PREMISE OF THE STUDY: The high biodiversity in the Baetic-Rifan hotspot of Mediterranean region is shaped by complex geological and climatic histories and has been a subject of recent intensive studies. However, very little is known about phylogenetic and biogeographic history of three rare and critically endangered cliff-dwelling species of Sonchus in section Pustulati in this region. METHODS: We investigated the genetic variation and phylogenetic relationships of populations based on nuclear (ITS/ETS) and plastid (3’trnL–ndhJ/ psaI–accD ) DNA sequences, and amplified fragment length polymorphisms (AFLPs). We performed a Bayesian relaxed molecular clock analysis with ITS data to estimate divergence times for major lineages. KEY RESULTS: ITS/ETS and AFLP phylogenies showed high concordance and contrasted with cpDNA data. The divergence between S. masguindalii and S. fragilis was dated at 5.48 Ma, between S. fragilis and S. pustulatus at 3.89 Ma, and between the Baetic and Rifan S. pustulatus at 1.18 Ma. Within each distribution area, AFLP data showed a relatively high genetic structuring and moderate genetic diversity, the latter being impoverished in the Baetic populations. CONCLUSIONS: Our results further confirm the hybrid origin of S. pustulatus , a critically endangered species. The origin and diversification of lineages appear to have occurred on the temporary land bridge that joined Iberian and North Africa during the Messinian Salinity Crisis (5.96–5.33 Ma) and the subsequent Zanclean flood that progressively refilled the Mediterranean Basin (5.33–3.60 Ma). The only Baetic populations of S. pustulatus most likely originated from the Rifan ones.Ministerio de Ciencia e Innovación (España) BES–2007–17066 CGL2006–00817 CGL2010-1651

Delocalized hypervalent silyl radical supported by amidinate and imino substituents

The reaction of the amidinato silylsilylene with a functionalized diaminochlorosilyl substituent [LSiSi(Cl){(NtBu)2C(H)Ph}] (1, L = PhC(NtBu)2) with ArN=C=NAr (Ar = 2,6-iPr2C6H3) in toluene afforded the delo-calized hypervalent silyl radical [LSi(-CNAr)2Si{(NtBu)2C(H)Ph}] (2). It possesses a hypervalent silyl radical, which delocalizes throughout the Si2C2 ring

L-Asparaginase delivered by Salmonella typhimurium suppresses solid tumors

Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor. L-asparaginase (L-ASNase), which primarily converts asparagine to aspartate, is an anticancer protein used to treat acute lymphoblastic leukemia. In this study, Salmonellae were engineered to express L-ASNase selectively within tumor tissues using the inducible araBAD promoter system of Escherichia coli. Antitumor efficacy of the engineered bacteria was demonstrated in vivo in solid malignancies. This result demonstrates the merit of bacteria as cancer drug delivery vehicles to administer cancer-starving proteins such as L-ASNase to be effective selectively within the microenvironment of cancer tissue

Snake prices and crocodile appetites: Aquatic wildlife supply and demand on Tonle Sap Lake, Cambodia

Commercial trade is a major driver of over-exploitation of wild species, but the pattern of demand and how it responds to changes in supply is poorly understood. Here we explore the markets for snakes from Tonle Sap Lake in Cambodia to evaluate future exploitation scenarios, identify entry points for conservation and, more generally, to illustrate the value of multi-scale analysis of markets to traded wildlife conservation. In Cambodia, the largest driver of snake exploitation is the domestic trade in snakes as crocodile food. We estimate that farmed crocodiles consume between 2.7 and 12.2 million snakes per year. The market price for crocodiles has been in decline since 2003, which, combined with rising prices for their food, has led to a reduced frequency of feeding and closure of small farms. The large farms that generate a disproportionate amount of the demand for snakes continue to operate in anticipation of future market opportunities, and preferences for snakes could help maintain demand if market prices for crocodiles rise to pre 2003 levels. In the absence of a sustained demand from crocodile farms, it is also possible that alternative markets will develop, such as one for human snack food. The demand for snakes, however, also depends on the availability of substitute resources, principally fish. The substitutability and low price elasticity of demand offers a relatively sustainable form of consumerism. Given the nature of these market drivers, addressing consumer preferences and limiting the protection of snakes to their breeding season are likely to be the most effective tools for conservation. This study highlights the importance of understanding the structure of markets and the behaviour of consumer demand prior to implementing regulations on wildlife hunting and trade

Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes.

Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice. Cisplatin increases the catalytic activity of caspase-3 and caspase-8 proteases and the production of free radicals, which were significantly suppressed by pretreatment with bucillamine. Bucillamine induces the intranuclear translocation of Nrf2 and thereby increases the expression of γ-glutamylcysteine synthetase (γ-GCS) and glutathione synthetase (GSS), which further induces intracellular antioxidant glutathione (GSH), heme oxygenase 1 (HO-1) and superoxide dismutase 2 (SOD2). However, knockdown studies of HO-1 and SOD2 suggest that the protective effect of bucillamine against cisplatin is independent of the enzymatic activity of HO-1 and SOD. Furthermore, pretreatment with bucillamine protects sensory hair cells on organ of Corti explants from cisplatin-induced cytotoxicity concomitantly with inhibition of caspase-3 activation. The auditory-brainstem-evoked response of cisplatin-injected mice shows marked increases in hearing threshold shifts, which was markedly suppressed by pretreatment with bucillamine in vivo. Taken together, bucillamine protects sensory hair cells from cisplatin through a scavenging effect on itself, as well as the induction of intracellular GSH

Pagkapit Sa Hangin

August 2021. COVID-19 delta wave overwhelms the only hospital in an unnamed island. The health workers have been working nonstop for over twenty-four hours. Then the delivery of oxygen tanks does not arrive. In the Temporary Treatment and Monitoring Facility (TTMF) of the public hospital, the doctor and two staff nurses decide to lower the oxygen levels of those whom they believe are going to die soon, in effect hastening these patients’ deaths. But their desperate attempt to save oxygen is found out by a watcher—a relative assigned to take care of their patient—who refuses to accept that nothing more can be done to save her father’s life