6,487 research outputs found
Time-resolved photoluminescence of the size-controlled ZnO nanorods
Size dependence of the time-resolved photoluminescence (TRPL) has been investigated for the ZnO nanorods fabricated by catalyst-free metalorganic chemical vapor deposition. The nanorods have a diameter of 35 nm and lengths in the range of 150 nm to 1.1 mum. The TRPL decay rate decreases monotonically as the length of the nanorods increases in the range of 150 to 600 nm. Decrease of the radiative decay rate of the exciton-polariton has been invoked to account for the results. (C) 2003 American Institute of Physics.X11100sciescopu
Symptomatic treatment of children with anti-NMDAR encephalitis.
Abstract
AIM:
We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
METHOD:
A retrospective chart review was undertaken at two tertiary paediatric hospitals in Australia and New Zealand. We included 27 children (12 males, 15 females; mean age at admission 7y 1mo) with anti-NMDAR antibodies in serum or cerebrospinal fluid with a typical clinical syndrome.
RESULTS:
Only two out of 27 patients were white, whereas 16 out of 27 patients were from the Pacific Islands/New Zealand Maori. The mean duration of admission was 69 days (10-224d) and 48% of patients (13/27) needed treatment in an intensive care setting. A mean of eight medications per patient was used for symptomatic management. Symptoms treated were agitation (n=25), seizures (n=24), movement disorders (n=23), sleep disruption (n=17), psychiatric symptoms (n=10), and dysautonomia (n=four). The medications used included five different benzodiazepines (n=25), seven anticonvulsants (n=25), eight sedatives and sleep medications (n=23), five antipsychotics (n=12), and five medications for movement disorders (n=10). Sedative and sleep medications other than benzodiazepines were the most effective, with a mean benefit of 67.4% per medication and a mean adverse effect-benefit ratio of 0.04 per medication. Antipsychotic drugs were used for a short duration (median 9d), and had the poorest mean benefit per medication of 35.4% and an adverse effect-benefit ratio of 2.0 per medication.
INTERPRETATION:
Long-acting benzodiazepines, anticonvulsants, and clonidine can treat multiple symptoms. Patients with anti-NMDAR encephalitis appear vulnerable to antipsychotic-related adverse effects. Pacific Islanders appear to have a vulnerability to anti-NMDAR encephalitis in our region
Bulk spectral function sum rule in QCD-like theories with a holographic dual
We derive the sum rule for the spectral function of the stress-energy tensor
in the bulk (uniform dilatation) channel in a general class of strongly coupled
field theories. This class includes theories holographically dual to a theory
of gravity coupled to a single scalar field, representing the operator of the
scale anomaly. In the limit when the operator becomes marginal, the sum rule
coincides with that in QCD. Using the holographic model, we verify explicitly
the cancellation between large and small frequency contributions to the
spectral integral required to satisfy the sum rule in such QCD-like theories.Comment: 16 pages, 2 figure
Baryon charge from embedding topology and a continuous meson spectrum in a new holographic gauge theory
We study a new holographic gauge theory based on probe D4-branes in the
background dual to D4-branes on a circle with antiperiodic boundary conditions
for fermions. Field theory configurations with baryons correspond to smooth
embeddings of the probe D4-branes with nontrivial winding around an S^4 in the
geometry. As a consequence, physics of baryons and nuclei can be studied
reliably in this model using the abelian Born-Infeld action. However,
surprisingly, we find that the meson spectrum is not discrete. This is related
to a curious result that the action governing small fluctuations of the gauge
field on the probe brane is the five-dimensional Maxwell action in Minkowski
space despite the non-trivial embedding of the probe brane in the curved
background geometry.Comment: 24 pages, LaTeX, 10 figures, v4: previously ignored effects of
coupling to RR-fields included, meson spectrum qualitatively changed, v5:
journal versio
Controlled selective growth of ZnO nanorod and microrod arrays on Si substrates by a wet chemical method
The use of a wet chemical method to selectively grow ZnO microrod and nanorod arrays on Si substrates is described. To control the size and position of the ZnO microrods and nanorods, polymethylmethacrylate (PMMA) submicron patterns were prepared on the Si substrates with an intermediate ZnO layer using e-beam lithography. Selective growth of the ZnO structures was achieved by the absence of ZnO nucleation sites on the PMMA mask, resulting in position-controlled growth of ZnO structures only on patterned holes where the ZnO layer was exposed. In addition, the diameters of the ZnO microrods were determined by the patterned hole size, and the diameters as small as 250 nm were obtained when a hole diameter of 250 nm was employed. The structural and optical characteristics of the ZnO microrods were further investigated using x-ray diffraction, transmission electron microscopy, and photoluminescence spectroscopy. (c) 2006 American Institute of Physics.open11107109sciescopu
Drop Traffic in Microfluidic Ladder Networks with Fore-Aft Structural Asymmetry
We investigate the dynamics of pairs of drops in microfluidic ladder networks
with slanted bypasses, which break the fore-aft structural symmetry. Our
analytical results indicate that unlike symmetric ladder networks, structural
asymmetry introduced by a single slanted bypass can be used to modulate the
relative drop spacing, enabling them to contract, synchronize, expand, or even
flip at the ladder exit. Our experiments confirm all these behaviors predicted
by theory. Numerical analysis further shows that while ladder networks
containing several identical bypasses are limited to nearly linear
transformation of input delay between drops, mixed combination of bypasses can
cause significant non-linear transformation enabling coding and decoding of
input delays.Comment: 4 pages, 5 figure
A Matrix Model for Baryons and Nuclear Forces
We propose a new matrix model describing multi-baryon systems. We derive the
action from open string theory on the wrapped baryon vertex D-branes embedded
in the D4-D8 model of large N holographic QCD. The positions of k baryons are
unified into k x k matrices, with spin/isospin of the baryons encoded in a set
of k-vectors. Holographic baryons are known to be very small in the large 't
Hooft coupling limit, and our model offers a better systematic approach to
dynamics of such baryons at short distances. We compute energetics and spectra
(k=1), and also short-distance nuclear force (k=2). In particular, we obtain a
new size of the holographic baryon and find a precise form of the repulsive
core of nucleons. This matrix model complements the instanton soliton picture
of holographic baryons, whose small size turned out to be well below the
natural length scale of the approximation involved there. Our results show
that, nevertheless, the basic properties of holographic baryons obtained there
are robust under stringy corrections within a few percents.Comment: 30 pages. v3: more comments added, published versio
The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding
The validity of the identification and classification of human cancer using antibodies to detect biomarker proteins depends upon antibody specificity. Antibodies that bind to the tumour-suppressor protein p16INK4a are widely used for cancer diagnosis and research. In this study we examined the specificity of four commercially available anti-p16INK4a antibodies in four immunological applications. The antibodies H-156 and JC8 detected the same 16 kDa protein in western blot and immunoprecipitation tests, whereas the antibody F-12 did not detect any protein in western blot analysis or capture a protein that could be recognised by the H-156 antibody. In immunocytochemistry tests, the antibodies JC8 and H-156 detected a predominately cytoplasmic localised antigen, whose signal was depleted in p16INK4a siRNA experiments. F-12, in contrast, detected a predominately nuclear located antigen and there was no noticeable reduction in this signal after siRNA knockdown. Furthermore in immunohistochemistry tests, F-12 generated a different pattern of staining compared to the JC8 and E6H4 antibodies. These results demonstrate that three out of four commercially available p16INK4a antibodies are specific to, and indicate a mainly cytoplasmic localisation for, the p16INK4a protein. The F-12 antibody, which has been widely used in previous studies, gave different results to the other antibodies and did not demonstrate specificity to human p16INK4a. This work emphasizes the importance of the validation of commercial antibodies, aside to the previously reported use, for the full verification of immunoreaction specificity
D3/D7 Quark-Gluon Plasma with Magnetically Induced Anisotropy
We study the effects of the temperature and of a magnetic field in the setup
of an intersection of D3/D7 branes, where a large number of D7 branes is
smeared in the transverse directions to allow for a perturbative solution in a
backreaction parameter. The magnetic field sources an anisotropy in the plasma,
and we investigate its physical consequences for the thermodynamics and energy
loss of particles probing the system. In particular we comment on the
stress-energy tensor of the plasma, the propagation of sound in the directions
parallel and orthogonal to the magnetic field, the drag force of a quark moving
through the medium and jet quenching.Comment: 29 pages + appendices, 5 figures. v2 Version to appear in JHEP, with
minor revisions, references added and typos correcte
Maxwell-Chern-Simons Vortices and Holographic Superconductors
We investigate probe limit vortex solutions of a charged scalar field in
Einstein-Maxwell theory in 3+1 dimensions, for an asymptotically AdS
Schwarzschild black hole metric with the addition of an axionic coupling to the
Maxwell field. We show that the inclusion of such a term, together with a
suitable potential for the axion field, can induce an effective Chern-Simons
term on the 2+1 dimensional boundary. We obtain numerical solutions of the
equations of motion and find Maxwell-Chern-Simons like magnetic vortex
configurations, where the magnetic field profile varies with the size of the
effective Chern-Simons coupling. The axion field has a non-trivial profile
inside the AdS bulk but does not condense at spatial infinity.Comment: 17 pages, 5 figures, version accepted for publication in JHE
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