1,600 research outputs found

    LES Modelling of Propagating Turbulence Premixed Flames using a Dynamic Flame Surface Density Model

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    A Dynamic flame surface density (DFSD) model, developed recently from experimental images for transient turbulent premixed flames, is implemented and tested using the large eddy simulation (LES) modelling technique. Numerical predictions from DFSD model are compared with those predicted using the flame surface density (FSD) sub-grid scale (SGS) model for reaction rate. In the SGS-DFSD model, dynamic formulation of the reaction rate is coupled with the fractal analysis of the flame front structure. The fractal dimension is evaluated dynamically from an empirical formula based on the sub-grid velocity fluctuations. A laboratory scale combustion chamber with inbuilt solid obstacles is used for model validation and comparisons. The flame is initiated from igniting a stichiometric propane/air mixture from stagnation. The results obtained with the DFSD model are in good comparisons with experimental data and the essential features of turbulent premixed combustion are well captured. It has also been observed that the SGS-DFSD model for reaction rate found to capture the unresolved flame surface density contributions. Further investigations are planned to examine and validate of the SGS-DFSD for different flow geometries

    Large perturbations in CO2 flux and subsequent chemosynthesis are induced in agricultural soil by the addition of elemental sulfur

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    The microbial contribution to soil organic matter has been shown to be much larger than previously thought and thus it plays a major role in carbon cycling. Among soil microorganisms, chemoautotrophs can fix CO2 without sunlight and can glean energy through the oxidation of reduced elements such as sulfur. Here we show that the addition of sulfur to soil results in an initial surge in production of CO2 through microbial respiration, followed by an order of magnitude increase in the capture of carbon from the atmosphere as elemental sulfur is oxidised to sulfate. Thiobacillus spp., take advantage of specific conditions to become the dominant chemoautotrophic group that consumes CO2. We discern the direct incorporation of atmospheric carbon into soil carbohydrate, protein and aliphatic compounds and differentiate these from existing biomass. These results suggest that chemoautotrophs can play a large role in carbon cycling and that this carbon is heavily influenced by land management practises

    Enhanced mitochondrial superoxide scavenging does not Improve muscle insulin action in the high fat-fed mouse

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    Improving mitochondrial oxidant scavenging may be a viable strategy for the treatment of insulin resistance and diabetes. Mice overexpressing the mitochondrial matrix isoform of superoxide dismutase (sod2(tg) mice) and/or transgenically expressing catalase within the mitochondrial matrix (mcat(tg) mice) have increased scavenging of O2(˙-) and H2O2, respectively. Furthermore, muscle insulin action is partially preserved in high fat (HF)-fed mcat(tg) mice. The goal of the current study was to test the hypothesis that increased O2(˙-) scavenging alone or in combination with increased H2O2 scavenging (mtAO mice) enhances in vivo muscle insulin action in the HF-fed mouse. Insulin action was examined in conscious, unrestrained and unstressed wild type (WT), sod2(tg), mcat(tg) and mtAO mice using hyperinsulinemic-euglycemic clamps (insulin clamps) combined with radioactive glucose tracers following sixteen weeks of normal chow or HF (60% calories from fat) feeding. Glucose infusion rates, whole body glucose disappearance, and muscle glucose uptake during the insulin clamp were similar in chow- and HF-fed WT and sod2(tg) mice. Consistent with our previous work, HF-fed mcat(tg) mice had improved muscle insulin action, however, an additive effect was not seen in mtAO mice. Insulin-stimulated Akt phosphorylation in muscle from clamped mice was consistent with glucose flux measurements. These results demonstrate that increased O2(˙-) scavenging does not improve muscle insulin action in the HF-fed mouse alone or when coupled to increased H2O2 scavenging

    Adsorption and Biodegradation of 1-Methyl Naphthalene Using Immobilized Pseudomonas macerans and Bacillus subtilis on Burnt Kaolin

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    This work is aimed at assessing the effect of incorporating Pseudomonas macerans and Bacillus subtilis on burnt kaolin (BK) during the biodegradation of 1-methyl naphthalene. The biodegradation was monitored by determining the concentration of CO2 released. Immobilized Pseudomonas macerans on BK released CO2 in the range of 0.72 - 0.83 mg/L, while this was 0.68 - 0.78 mg/L with Bacillus subtilis; for the degradation alone the range was 0.39 - 0.46 mg/L after 72 h. Generally, the concentration of carbon (IV) oxide released by the immobilized Pseudomonas macerans was more than that by Bacillus subtilis. Therefore, immobilization using BK resulted to better removal of the organic pollutant. The FTIR indicated presence of new peaks within the regions 3272-3265cm-1 and 1647-1640cm-1 attributed to overlapping of hydroxyl (-OH) and carbonyl (C=O) stretching in carboxylic acid. The absorptions within 1114-1088 cm-1, and at 1408cm-1 are due to C-O stretching and O-H in plane bending of carboxylic acid respectively. The use of kaolin for environmental clean-up of organic pollutants will enhance the value chain of solid minerals in Nigeria

    Superconformal Flavor Simplified

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    A simple explanation of the flavor hierarchies can arise if matter fields interact with a conformal sector and different generations have different anomalous dimensions under the CFT. However, in the original study by Nelson and Strassler many supersymmetric models of this type were considered to be 'incalculable' because the R-charges were not sufficiently constrained by the superpotential. We point out that nearly all such models are calculable with the use of a-maximization. Utilizing this, we construct the simplest vector-like flavor models and discuss their viability. A significant constraint on these models comes from requiring that the visible gauge couplings remain perturbative throughout the conformal window needed to generate the hierarchies. However, we find that there is a small class of simple flavor models that can evade this bound.Comment: 43 pages, 1 figure; V3: small corrections and clarifications, references adde

    Groundwater resources assessment using integrated geophysical techniques in the southwestern region of Peninsular Malaysia.

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    Combined geophysical techniques such as multi-electrode resistivity, induced polarization, and borehole geophysical techniques were carried out on volcano-sedimentary rocks in the north of Gemas as part of the groundwater resource’s investigations. The result identifies four resistivity units: the tuffaceous mudstone, tuffaceous sandstone, the tuff bed, and the shale layer. Two types of aquifer systems in terms of storage were identified within the area: one within a fracture system (tuff), which is the leaky area through which vertical flow of groundwater occurs, and an intergranular property of the sandy material of the aquifer which includes sandstone and tuffaceous sandstone. The result also reveals that the aquifer occupies a surface area of about 3,250,555 m2 with a mean depth of 43.71 m and a net volume of 9.798 × 107 m3. From the approximate volume of the porous zone (28 %) and the total aquifer volume, a usable capacity of (274.339 ± 30.177) × 107 m3 of water in the study area can be deduced. This study provides useful information that can be used to develop a much broader understanding of the nature of groundwater potential in the area and their relationship with the local geology

    Potential health impacts of heavy metals on HIV-infected population in USA.

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    Noninfectious comorbidities such as cardiovascular diseases have become increasingly prevalent and occur earlier in life in persons with HIV infection. Despite the emerging body of literature linking environmental exposures to chronic disease outcomes in the general population, the impacts of environmental exposures have received little attention in HIV-infected population. The aim of this study is to investigate whether individuals living with HIV have elevated prevalence of heavy metals compared to non-HIV infected individuals in United States. We used the National Health and Nutrition Examination Survey (NHANES) 2003-2010 to compare exposures to heavy metals including cadmium, lead, and total mercury in HIV infected and non-HIV infected subjects. In this cross-sectional study, we found that HIV-infected individuals had higher concentrations of all heavy metals than the non-HIV infected group. In a multivariate linear regression model, HIV status was significantly associated with increased blood cadmium (p=0.03) after adjusting for age, sex, race, education, poverty income ratio, and smoking. However, HIV status was not statistically associated with lead or mercury levels after adjusting for the same covariates. Our findings suggest that HIV-infected patients might be significantly more exposed to cadmium compared to non-HIV infected individuals which could contribute to higher prevalence of chronic diseases among HIV-infected subjects. Further research is warranted to identify sources of exposure and to understand more about specific health outcomes

    Effects of inaccuracies in arterial path length measurement on differences in MRI and tonometry measured pulse wave velocity

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    Abstract Background Carotid-femoral pulse wave velocity (cf-PWV) and aortic PWV measured using MRI (MRI-PWV) show good correlation, but with a significant and consistent bias across studies. The aim of the current study was to evaluate whether the differences between cf.-PWV and MRI-PWV can be accounted for by inaccuracies of currently used distance measurements. Methods One hundred fourteen study participants were recruited into one of 4 groups: Type 2 diabetes melltus (T2DM) with cardiovascular disease (CVD) (n = 23), T2DM without CVD (n = 41), CVD without T2DM (n = 25) and a control group (n = 25). All participants underwent cf.-PWV, cardiac MRI and whole body MR angiography(WB-MRA). 90 study participants also underwent aortic PWV using MRI. cf.-PWVEXT was performed using a SphygmoCor device (Atcor Medical, West Ryde, Australia). The true intra-arterial pathlength was measured using the WB-MRA and then used to recalculate the cf.-PWVEXT to give a cf.-PWVMRA. Results Distance measurements were significantly lower on WB-MRA than on external tape measure (mean diff = −85.4 ± 54.0 mm,p < 0.001). MRI-PWV was significantly lower than cf.-PWVEXT (MRI-PWV = 8.1 ± 2.9 vs. cf.-PWVEXT = 10.9 ± 2.7 ms−1,p < 0.001). When cf.-PWV was recalculated using the inter-arterial distance from WB-MRA, this difference was significantly reduced but not lost (MRI-PWV = 8.1 ± 2.9 ms−1 vs. cf.-PWVMRA 9.1 ± 2.1 ms−1, mean diff = −0.96 ± 2.52 ms−1,p = 0.001). Recalculation of the PWV increased correlation with age and pulse pressure. Conclusion Differences in cf.-PWV and MRI PWV can be predominantly but not entirely explained by inaccuracies introduced by the use of simple surface measurements to represent the convoluted arterial path between the carotid and femoral arteries

    Household Expenditure on Treatment of Presumptive Malaria in a Rural Community of North-western Nigeria

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    Background: Malaria is endemic in Nigeria and there is a vicious cycle between it and poverty. It contributes towards poverty, while poverty influences the risk of its infection. Majority of Nigerians, 70%, live in rural areas, below poverty line. They earn less than $1.25 a day. Subsistence farming is their main occupation. The cost of malaria treatment represents a significant portion of their income.Objective: This study was conducted to assess the direct cost of presumptive malaria treatment on households in Gimba Village of Soba Local Government Area of Kaduna State, Nigeria.Methodology: A cross-sectional descriptive study conducted during community diagnosis posting of final year medical students of Ahmadu Bello University, Zaria in July 2012. An interviewer- administered questionnaire was used to collect data from household heads.Results: Most of the respondents (69.7%) were farmers. A large proportion of the respondents (47.3%) earned between N10,000.00 to N20,000.00. monthly. The average household size was 6 while the average number of presumptive malaria cases per household per year was 13. On average, the direct cost of presumptive malaria treatment alone, consumes 4.9 % of the annual income of household heads. There was a statistically significant association between cost of treatment and place of seeking treatment (p &lt;0.001).Conclusion: The direct cost of presumptive malaria treatment alone consumed a large proportion of the meagre annual income of households in the study area. For effective malaria control in Nigeria, free or subsidized malaria treatment and rural health insurance scheme are recommended.Keywords: Household, expenditure, Treatment, presumptive malaria, Gimba Community, Nigeria

    Greenhouse gas emissions of realistic dietary choices in Denmark: the carbon footprint and nutritional value of dairy products

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    Background: Dairy products are important in a healthy diet due to their high nutritional value; they are, however, associated with relatively large greenhouse gas emissions (GHGE) per kg product. When discussing the need to reduce the GHGE caused by the food system, it is crucial to consider the nutritional value of alternative food choices. Objective: The objective of this study was to elucidate the role of dairy products in overall nutrition and to clarify the effects of dietary choices on GHGE, and to combine nutritional value and GHGE data. Methods: We created eight dietary scenarios with different quantity of dairy products using data from the Danish National Dietary Survey (1995–2006). Nutrient composition and GHGE data for 71 highly consumed foods were used to estimate GHGE and nutritional status for each dietary scenario. An index was used to estimate nutrient density in relation to nutritional recommendation and climate impact for solid food items; high index values were those with the highest nutrient density scores in relation to the GHGE. Results: The high-dairy scenario resulted in 27% higher protein, 13% higher vitamin D; 55% higher calcium; 48% higher riboflavin; and 18% higher selenium than the non-dairy scenario. There was a significant correlation between changes in calcium and changes in vitamin D, selenium, and riboflavin content (P=0.0001) throughout all of the diets. The estimated GHGE for the dietary scenario with average-dairy consumption was 4,631 g CO2e/day. Conclusions: When optimizing a diet with regard to sustainability, it is crucial to account for the nutritional value and not solely focus on impact per kg product. Excluding dairy products from the diet does not necessarily mitigate climate change but in contrast may have nutritional consequences
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