Phylogenetic and chronological analysis of proteins causing Alzheimer's, Parkinson's and Huntington's diseases

It is evident that Neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's) have many similarities at cellular and molecular level as they carry parallel mechanisms including protein aggregation and inclusion body formation caused by protein mis-folding. The main objective of this study was to have detailed insight on variation and resemblance among these proteins. One hundred and four protein sequences, both directly and indirectly involved in disease mechanism to perform phylogenetic analysis revealing insight on evolutionary relationship among these proteins, were selected. The percentage of replicate trees, in which the associated taxa clustered together in the bootstrap test, was 1000 replicates. Various statistical tests were performed for the confirmation of results e.g., Tajma's Neutrality Test showed D gt 6, nucleotide diversity π gt 0.6 and ps value as greater than 1. Phylogenetic analysis showed that the protein sequences of neurodegenerative diseases had high sequence similarity and identity to each other as depicted by the evolutionary tree. It showed the similar mechanism of evolving from each other and had similar mechanism of generating mis-folding leading towards symptoms of disease

Mimicry Matters: Postcolonial Borrowing and Backfiring

This article explores how postcolonial literary criticism’s borrowing of its different forms of cultural (such as poststructural and postmodern) and materialist/Marxist resistance from Europe, with which it has attempted to counter colonial and neocolonial hegemonic dominations, ultimately works as a boomerang to write back to the once-colonized people in one way or another. For this purpose, this paper will use Homi Bhabha’s theory of mimicry in which the borrowing of European language simultaneously leads to the subversion of colonial domination as well as a subversion of own self. Like Bhabha’s mimicry, postcolonial criticism often tends to focus more on its indebtedness to Europe rather than on attempts to subvert European ideologies which became complicit in colonial domination. Like Bhabha’s theory, postcolonial borrowing of ideas of resistance from Europe focuses more on once-colonized peoples’ inferiority and failure only to produce a kind of self-subversion. Bhabha’s immigrant subject attempts a self-assertion from a hybrid identity position and finally acknowledges an inescapable marginalization. This article will show when later postcolonial criticism often borrows from Europe to ironically assert cultural difference, native agency or local specificity, it turns out once again to lead to self-subversion. By using an observation of a number of recent postcolonial books and articles and with reference to a number of influential postcolonial writers, theorists and critics this paper aims to raise concern about the development of postcolonial self-subversion in certain key areas of postcolonial appropriation of European poststructural, postmodern and Marxist politics

RESPONSE OF SUMMER ONION TO INTEGRATED NITROGEN MANAGEMENT

A Thesis Submitted to the Faculty of Agriculture, Sher-e-Bangla Agricultural University, Dhaka, in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN SOIL SCIENCE SEMESTER: JANUARY-JUNE, 2008Response of summer onion (41/inn) cepu var. BAR] Piaz-2) to integrated nhlrogen management was assessed iii a held experiment carried ott t on a Si liv U lay I .oam soil having p1-1 6.0 lit Shcr-e-E3angla Agricultural L.niversity Farm. Dhaka during the kiwi/f season of 2007. 1.rea. cowdunu (CD) and veriiticonipost (VU) were combined in a way to supply N at 120 kg ha' from the sources such no urea. C!) and kg from urea. CD and VU: 100 kg from urea with 20 kg from CD or VC. 80 I%L, from urea '. ith 40 kg from CD or VU. 60 kg from urea with 60 kg ironi UI) or \U. 40 kg from urea t itli 80 LL, . from ('I) or VU arraitued lit a RCI3I) desint lilt three repiicaiions and tclve treatnenis. the results indicated that IlliI\iItttllll bulb ield [2.]6 ha and stover yield (546 I ha ) ol summer onion were obtamed iii treatment receiving 80 kg N ha 'from urea with -10 kg N ha suhstiltmied h ('I) ( T- [bllowed In the treatment receiving 80 kg N ha from urea with .10 kg N ha substituted by VU (I). Comparing with other fertilizer treatments, the yields t ere sign Iieantiv lower in treatments where N from urea source was below 50%. ihe highest N. P. K and S content in bulb (2.30%. 0. I 85%. I .7 1% and 0.96%, respectivel> and in leaf (2.91%. 0.183%. 2.450 1, and 0.98%. resjwetivelv "as recorded in trea(nient 1< ibI lowed In L.. Similarly, the N. P. K and S uptake 72.78. 5.53. 55.88 and 28.93 kc.z ha . respceti clvi by onion plants at hatvest stage was also siwiilie:uitiv 01<0.0 I ) greater in treatments itceiving 80 ku N lia Iiomn urea with 40 kg from CD (l ) Ibllowed by treatment 1 thus tile data suggest that integrated use of N 80 kg from urea with 40 kg from Cl) or 80 kg 1mm urea with 40 kg from 'IC has produced maximum yields and is therefore reconlmended for advantageous onion pt'odtie lion

Land Use Land Cover Analysis of Peri-Urban Area of Murad Memon Goth-Karachi

Agricultural activities are historically practiced in Murad Memon Goth i.e. the peri-urban (PU) region of Karachi, located on the northwestern side of Malir River. This study seeks to examine the agricultural and nonagricultural land use land cover (LULC) of the peri-urban region. A very high-resolution satellite image of the SAS planet has been used to digitize on ArcMap 10.8 for the LULC of the study area. The obtained results revealed that the estimated settlement sprawl had increased up to 9.6% in Murad Memon between 2013 and 2021. The maximum cropland area was observed by 38.86%, whereas the lowest farmhouse area was 1.76% in 2013. The highest cropland area was noted at 26.11%, but the lowest dairy farm area was observed as 1.14% in 2021. The LULC of peri-urban areas will be useful in examining Land use land cover change in the study area and identifying the encroachment of settlements in the study area. Keywords; Urban and peri-urban agriculture, Land-use land cover analysis, Object-Based, Urban Growth Boundaries, Urban Sprawl

PASSIVE ADAPTATIONS IN THE URBAN SOCIETIES OF BANGLADESH CONSIDERING KITCHEN AREA

Residence carries cultural information through its structure and activity. The kitchen, an indispensable part of a residence is used to cook food and food is the presenter of a country’s habit and nature. This study is an attempt to investigate the transformation of the spatial organization of kitchen area considering Dhaka, Bangladesh residences. The study is based on primary data collected from different types of apartments in Dhaka City. Thirty households were surveyed using a structured questionnaire to investigate the kitchen activities, workable space, comfort while working in the kitchen. The study has institute that once upon a time, kitchen was useful for different activities and it was given equal importance while designing the living rooms or bedrooms. But slowly kitchen has become one of the most hazardous space in a residence, in the context of Dhaka and the situation are getting worse. The outcome of the study is expected to raise awareness on setting, design of kitchen area appropriately among architects & planners

Clinicopathological Study of Patients Presenting with Adnexal Masses

Background: To assess the clinicopathological outcome of women with adnexal masses . Method: In this observational study patients with a diagnosis of adnexal mass, who underwent laparotomy, were included. All the patients were evaluated by a complete history, general abdominal and pelvic examination, followed by ultrasonography. Their preoperative findings are then correlated with surgical findings and histopathological diagnosis. Descriptive statistics are applied and results shown in the form of frequencies and percentages. Result: In 50 patients commonest presenting symptom was pain abdomen followed by mass abdomen. Ultrasound features correlate well with histopathological features. Majority (94.6%) patients had benign adnexal pathology and 5.4% had malignant pathology. Most common neoplasms were surface epithelial tumours followed by dermoid cyst. Conclusion:Demographic detail, ultrasonography and CA-125 are good preoperative indicators of malignant nature or benign nature of adnexal masses. Most common adnexal tumours are surface epithelial tumours followed by dermoid cysts and malignant tumours are common in postmenopausal group

An overview on medicinally important plant: Jojoba (Simmondsia chinensis Link) Schneider

Simmondsia chinensis or Jojoba is the diaceous, perennial, slow growing and evergreen shrub and indigenous plant of California, United States and Mexico’s Sonoran Desert. Jojoba comprises nitrile glycosides groups called simmondsin’s compounds, stanols, sterols, toccopherols and flavonoids. The extracts of leaves, root and latex of jojoba possess anti-microbial, antiviral, anti-oxidant, anti-tumor properties. Various cosmetic formulation use jojoba as an important element of their product to enhance their moisturizing potential. Jojoba is applied for the treatment of psoriasis and acne-prone skin lesion. jojoba leaves and meal can be used as staple food and possess possible medicinal potentials. Jojoba oil is growing non-palatable oil, utilized as an unrefined substance for the production of biodiesel and development of the development of cleansers, plastics, environment friendly power and ointments. Its worldwide production is developing quickly and is supposed to arrive at 22,000 tons by 2022. This review focuses on the pharmacological medicinal and economic benefits of Jojoba

The association of serum ferritin with preeclampsia and its severity

Background: Preeclampsia, a pregnancy-related condition with heightened blood pressure and organ damage after 20 weeks, prompts concern. Serum ferritin, an iron-storing protein, gauged by blood tests, mirrors iron levels. Investigating link before conception between serum ferritin and preeclampsia could impact how we identify, manage, and treat this condition during pregnancy. Study aimed to assess the association of serum ferritin with preeclampsia and its severity. Methods: This case-control study was conducted in Bangabandhu Sheikh Mujib medical university hospital and Dhaka medical college hospital, Dhaka, Bangladesh from July 2011 to June 2012. A total of 100 pregnant women, comprising 50 cases (Preeclamptic) and 50 controls (Normal pregnant women), were purposively included as study subjects. Data analysis was performed using SPSS version 23.0. Results: In the case group, 64% were with mild and 36% with severe preeclampsia. Mean serum ferritin was significantly higher in cases than in controls (p&lt;0.001); 76% of cases had elevated serum ferritin, compared to 44% in controls (p=0.001). Severe preeclampsia group had a mean serum ferritin of 192.8, mild preeclampsia group had 86.1, and normal pregnant women had 21.7 ng/ml, indicating higher serum ferritin with preeclampsia severity (p&lt;0.001). Conclusions: Preeclamptic cases exhibit significantly elevated serum ferritin levels, with a fourfold increased likelihood compared to normal pregnancies. Furthermore, the severity of preeclampsia is associated with higher serum ferritin concentrations in comparison to uncomplicated pregnancies

Fintech for Sustainability in Business and Economics Research: Trends and Future Agendas

Purpose: Fintech for sustainability is pivotal for business and economics as it harnesses technology to drive environmentally and socially responsible practices while enhancing economic efficiency and growth. This paper discusses the research trends and future research implications of fintech in sustainable economic operations. Methods: This study extracted scholarly articles from the Scopus database and adopted the PRISMA framework and bibliographic analysis to uncover publication trends, research, affiliation, geographical circumstances, keywords trends, thematic trends, and bibliographic coupling to assess current practices and pinpoint future research directions of fintech to adopt the wider sustainability practices in business and economy. Results: Steady progress has been made in developing fintech applications to achieve sustainability. There is notable research collaboration in both developing and developed economies. Recent keyword trends indicate a growing interest in sustainability and digital transformation. The thematic map demonstrates that the digital economy is a well-established topic. However, there is a need for new research in financial technology-based climate solutions to address significant sustainability gaps. This study identified the impact of emerging financial technologies on sustainability as a widely researched area. We suggested the connection between sustainability and the fintech ecosystem, sustainable financial inclusion, open fintech innovation, and fintech stability as potential areas for future research to expedite fintech adoption in sustainability goals. Implications: Researchers, regulators, and policymakers can utilize the conclusions drawn from the research questions to craft a distinctive framework outlining strategic approaches and actionable plans for developing fintech policies that facilitate faster adoption of sustainability practices