Book prefaces in basic, applied and social sciences: A genre-based study

This is the final version. Available from IDOSI Publications via the link in this recordGenre- based studies have recently focused on different types of professional and academic texts to identify their communicative purpose(s), generic structure and linguistic features. However, analyzing the generic and linguistic structure of book prefaces as a subcategory of academic genres seems to have been significantly underresearched. This study focuses on academic book prefaces in three disciplines of management, metallurgy and mathematics to identify their generic structure, linguistic features and potential disciplinary differences. Identifying similar generic structure for book prefaces in the three disciplines, the researchers suggest that book prefaces in the above-mentioned areas are very similar in terms of their communicative purpose(s), generic structure and readers' expectation. Furthermore, the study did not identify any significant difference in the use of the moves and steps among the book prefaces in the three disciplines on the whole, which suggests that writers in the three disciplines generally use the same moves and steps with rather similar frequencies. Finally, analyzing the generic structure and linguistic features of book prefaces indicated that book prefaces fulfill a promotional purpose besides their common informative purpose

Un examen de las perspectivas del profesorado sobre la representación de género en un producto cultural digital –Achieve 3000- y su impacto en el estudiantado de la escuela preparatoria de inglés en la Universidad de Haliç de Turquía

This study investigates the effect of digital cultural commodities on English language learners in the preparatory program of Haliç University from a gender perspective. The point of view of English language teachers of preparatory program on the function of gender in digital English learning commodity, Achieve3000, is examined in this paper. The usage of digital commodities in the classroom is a way to improve student engagement and language learning. The study investigates how digital learning resources are effective for language learning and how they represent gender norms and stereotypes. English teachers perceive Achieve3000 positively for language learning, though reservations exist about its effectiveness in reading skill development and identifying student needs.Este estudio investiga el efecto de los productos culturales digitales en el estudiantado de inglés del programa preparatorio de la Universidad de Haliç desde una perspectiva de género. Se examina el punto de vista del profesorado de inglés del programa preparatorio sobre la función del género en el producto digital de aprendizaje de inglés, Achieve3000. El uso de productos digitales en el aula es una forma de mejorar la participación estudiantil y el aprendizaje del idioma. El trabajo investiga la efectividad de los recursos digitales de aprendizaje para el estudio del idioma y la manera en que representan normas y estereotipos de género. El profesorado de inglés percibe Achieve3000 de manera positiva para el aprendizaje del idioma, aunque existen reservas sobre su efectividad en el desarrollo de habilidades de lectura y en la identificación de necesidades de los estudiantes

Design and In-vitro Evaluation of Bilayer Floating Tablet Containing Mucoadhesive Microparticles of Olanzapin e.

Introduction: The purpose of this article was to design a bilayer floating- drug delivery system using mucoadhesive microparticles of olanzapine as a model drug. Methods and Results: Mucoadhesive Microparticles were fabricated with coacervation method by using of mucoadhesive polymers such as sodium bicarbonate, chitosan and ethyl cellulose. The floating layer containing sodium bicarbonate, HPMC, carbapol, PVP and olanzapine mucoadhesive microparticles was compressed and an immediate release layer was added and then both layers were compressed. Floating properties of the tablets, the in vitro drug release, buoyancy lag-time and swelling index were evaluated. The results showed that incorporation of olanzapine mucoadhesive microparticles in floating tablet improved the release kinetic to biphasic so the drug was immediately release in 30 min after floating and lasted more than 8 hours. Also the release of olnzapine was  based on zero order kinetic. This suggested the synergic effect of micro particulate system as well as floating property in long time drug release in gastric fluid. Conclusions: This kind of tablet is suitable for long term delivery of olanzapine in upper gastric parts or segments

The prevalence and associated factors of microsatellite instability in ovarian epithelial cancers detected by molecular genetic studies in a sample of Iranian women

Background: Microsatellite instability, the main genetic element in HNPCC syndrome, is associated with a number of cancers, including ovarian epithelial carcinomas. These cancers have distinct characteristics compared to non-MSI related ones. Objectives: The present study aims at determining the prevalence of microsatellite instability in ovarian carcinomas and their associated factors in Iranian patients. Methods: Paraffin-embedded blocks, belonging to 37 patients with definite diagnosis of ovarian epithelial cancers, were retrieved from the archives. After DNA extraction from tumor tissue and PCR reaction, the results were assessed in accordance with melting curve analysis. Subsequently, the relationship among microsatellite status and tumor histology, grade, stage, and size were investigated statistically. Results: The predominant histological type was serous histology. Four out of 37 carcinomas were microsatellite unstable (10.8) and only 1 was MSI-high type (2.1). The MSI was more frequent among younger patients with unilateral, non-serous histology, non-high grade, and stage I tumors without omental involvement. After statistical analysis, the only significant relationship was found between histological type (non-serous) and microsatellite status. Conclusions: Microsatellite stable and unstable ovarian cancers may have different associations with various factors in a sample of Iranian women. The identification of these characteristics may help narrow down indications to test this prognostic and predictive genetic error. © 2017, Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

An Innovative Approach to Clinical Practice Guideline Adaptation in the Nursing Profession in a Developing Country

Introduction: Healthcare professionals should seek the necessary resources to improve the quality of care. Given the cultural, social, and economic differences, in every health care system, there are increasing needs for the adapted versions of clinical practice guidelines (CPGs). This study aimed to introduce an innovative CPG adaptation approach for nurses working in a developing country. Methods: This study is comprised of three sections: a. An extensive systematic search of the literature, b. The adaptation process, c. Interviews, which were held with stakeholders, users and/or the target population. We applied all of the stages of guideline adaptation process according to Adaptation Resource Toolkit, with the integration of the findings of a systematic literature search and a qualitative content analysis in an "adolopted" new CPG. Results: In this study, we applied a mix of three methods namely adoption, adaptation and development (adolopment) of recommendations to save time, cost, and manpower efficiently. Moreover, we integrated the utilized qualitative research method and literature review with the adolopment approach to develop the recommendations. Conclusion: Given there is a paucity of nursing clinical practice guidelines (NCPGs) in the nursing management of cancer therapy-induced mucositis and to save time and costs, the findings emerging from the adoption, adaptation, and de novo guideline development by a panel of experts and qualitative content analysis (QCA) method were integrated to achieve a more comprehensive nursing practice guideline

The prevalence and associated factors of microsatellite instability in ovarian epithelial cancers detected by molecular genetic studies in a sample of Iranian women

Background: Microsatellite instability, the main genetic element in HNPCC syndrome, is associated with a number of cancers, including ovarian epithelial carcinomas. These cancers have distinct characteristics compared to non-MSI related ones. Objectives: The present study aims at determining the prevalence of microsatellite instability in ovarian carcinomas and their associated factors in Iranian patients. Methods: Paraffin-embedded blocks, belonging to 37 patients with definite diagnosis of ovarian epithelial cancers, were retrieved from the archives. After DNA extraction from tumor tissue and PCR reaction, the results were assessed in accordance with melting curve analysis. Subsequently, the relationship among microsatellite status and tumor histology, grade, stage, and size were investigated statistically. Results: The predominant histological type was serous histology. Four out of 37 carcinomas were microsatellite unstable (10.8) and only 1 was MSI-high type (2.1). The MSI was more frequent among younger patients with unilateral, non-serous histology, non-high grade, and stage I tumors without omental involvement. After statistical analysis, the only significant relationship was found between histological type (non-serous) and microsatellite status. Conclusions: Microsatellite stable and unstable ovarian cancers may have different associations with various factors in a sample of Iranian women. The identification of these characteristics may help narrow down indications to test this prognostic and predictive genetic error. © 2017, Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

The Perceived Health Needs of Primiparous Mothers Referring to Primary Health Care Centers: A Qualitative Study

Background: Since the first step in meeting the health needs of primiparous women involves understanding their conditions, the present study aimed to determine the health needs of primiparous women from their own viewpoints. Methods: This study had a qualitative approach based on the conventional qualitative content analysis method, in which the purposive sampling method was used. Data were collected by semi-structured interviews. Data saturation was achieved by interviewing 12 participants. To ensure the study was rigorous, the four criteria of credibility, dependability, confirmability, and transferability were taken into account. Results: The findings of this study consisted of 150 codes, 19 subcategories, and 6 categories, as follows: 1) the intense need for social support, 2) the need for prior preparation for pregnancy, 3) fears and worries, 4) the necessity of the availability of the needed infrastructures and requirements in the health center, 5) falling in love with the baby, and 6) seeking information from appropriate sources. Conclusion: The present study showed that primiparous women need to receive more social and psychological support from family members and healthcare workers and that it is essential to improve the available infrastructures and services in healthcare centers and to provide the needed counseling to pregnant mothers to enable them to go through the pregnancy period smoothly

Corrigendum to: “The Prevalence of Internet Addiction and Its Relations to the Self Esteem and Life Satisfaction in Students of a Medical University”

Using internet has a growing popularity, especially among students. The aim of this study was to determine the prevalence of internet addiction and its relationship with the level of self esteem and life satisfaction in students of lorestan university of medical sciences in Iran. A cross-sectional study, with applying stratified sampling and then multi-stage cluster sampling method was performed. The sample size was 160. Four questionnaires (Demographic characteristics, Internet Addiction Test (IAT) by Dr. Kimberly Young, Rosenberg's Self esteem Scale and Diener’s Life Satisfaction Scale) were used to collect data, the software spss 16 was used for data analysis. Prevalence of internet addiction was 10%, and this problem was more prevalent in male students (P˂0.05). Moreover, there was a significant and adverse relation between internet addiction score and self esteem score (P=0.015), and life satisfaction score (P=0.012). There was a significant and direct relationship between life satisfaction and self esteem (P=0.001). Young people should be encouraged to use the internet as a more useful and efficient tool and become aware of the internet and its harmful effects.

Pulmonary Hypertension due to a Pulmonary Artery Leiomyosarcoma: A Case Report

Background. Primary pulmonary artery sarcomas are very rare and their histologic type, called leiomyosarcoma, is even rarer. Case Report. A 64-year-old woman presented with progressive weakness, fatigue, malaise, and dyspnea, and a marked elevation of pulmonary artery pressure was admitted. She was initially diagnosed with chronic pulmonary thromboembolism and chest computed tomography (CT) scan revealed that lobulated heterogeneous left hilar mass extended to precarinal and subcarinal space. MRI demonstrated a polypoid lesion at trunk with extension to left main pulmonary artery and its first branch. She was operated, a yellowish-shiny solid mass in pulmonary trunk was seen intraoperatively, and pulmonary endarterectomy was performed. Her tumor was pathologically diagnosed as pulmonary artery leiomyosarcoma. She died 3 months later after one chemotherapy course. Conclusion. Initially, the patient underwent surgery due to pulmonary embolism but, during the operation, the observed mass increased the probability of pulmonary artery neoplasm. Clinicians must consider pulmonary artery sarcoma when making the differential diagnosis for patients with pulmonary arteries masses. In addition to clinical prediction scores and CT and MRI findings to identify the patients with pulmonary artery sarcoma, PET scanning is the diagnosis of choice in differentiating embolism and neoplasm and is strongly recommended in these patients