Non-Berwaldian Randers metrics of Douglas type on four-dimensional hypercomplex Lie groups

In this paper we classify all non-Berwaldian Randers metrics of Douglas type arising from invariant hyper-Hermitian metrics on simply connected four-dimensional real Lie groups. Also, the formulas of the flag curvature are given and it is shown that, in some directions, the flag curvature of the Randers metrics and the sectional curvature of the hyper-Hermitian metrics have the same sign

Mitochondrial apoptosis induced by Chamaemelum nobile extract in breast cancer cells

Chamaemelum nobile (Asteraceae) commonly known as ‹Roman chamomile› is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. The present study was carried out to investigate the anticancer as well as apoptotic activity of ethyl acetate fraction of C. nobile on different cancerous cell lines. The cells were treated with varying concentrations (0.001-0.25 mg/mL) of this fraction for 24, 48 and 72 h. Apoptosis induced in MCF-7 cells following treatment with ethyl acetate fraction was measured using Annexin V/PI, flowcytometry and western blotting analysis. The results showed that C. nobile ethyl acetate fraction revealed relatively high antiproliferative activity on MCF-7 cells; however, it caused minimal growth inhibitory response in normal cells. The involvement of apoptosis as a major cause of the fraction-induced cell death was confirmed by annexin-V/PI assay. In addition, ethyl acetate fraction triggered the mitochondrial apoptotic pathway by decreasing the Bcl-2 as well as increasing of Bax protein expressions and subsequently increasing Bax/Bcl-2 ratio. Furthermore, decreased proliferation of MCF-7 cells in the presence of the fraction was associated with G2/M phase cell cycle arrest. These findings confirm that ethyl acetate fraction of C.nobile may contain a diversity of phytochemicals which suppress the proliferation of MCF-7 cells by inducing apoptosis. © 2016 by School of Pharmacy Shaheed Beheshti University of Medical Sciences and Health Services

Study of zinc deficiency in pregnant women

Zinc is one of the elements necessary for growth and health in human. Some evidences indicate that the zinc deficiency is one of real difficulties for the public health in developed and developing countries. Since the pregnant women are more at risk by the zinc deficiency, and this can cause many problems, in this study we tried to find out the rate of zinc deficiency in pregnant women within the region. This research project was analytical-descriptive study which was done on the 400 pregnant women whom referred to Zahedan Ghods hospital. A questionnaire was set up for each case which contained the following items, mother age, pregnancy age, numbers of deliveries, education, and consumption of iron tablet during pregnancy. The serum zinc level in each mother in this project was determined by atomic absorption technique. Prevalence of zinc deficiency among the pregnant women was 49%. Statistical analysis indicated that zinc deficiency had correlation with mother age, term of pregnancy and iron consumption. But zinc deficiency showed no correlation with numbers of deliveries and education. © Iranian Journal of Public Health. All rights reserved

Analysis of a Bidirectional DC-DC Converter with High Voltage Gain

A novel bidirectional DC-DC converter with high conversion ratio is proposed in this paper. The proposed converter uses the three windings coupled-inductor to achieved high voltage conversion ratio. The primary side consist of a winding and secondary side consist of two windings, which these two windings are series to achieved high voltage gain.In the boost mode, a capacitor is parallel charged and series discharged by the coupled inductor. Thus, high step-up voltage gain can be achieved with an appropriate duty ratio. In the buck mode, a capacitor is series charged and parallel discharged by the coupled inductor. The bidirectional converter can have high step-down voltage gain.The stress voltage of main switches can be reduced, and efficiency can be improved. The operating principle and the steady-state analyses of the voltage gain are discussed. Finally, in 24V for low voltage, and 400V for high voltage, and 200W for output power, this converter is simulated in MATLAB

Peningkatan Aktivitas Peserta Didik dalam Pembelajaran IPA Menggunakan Metode Demonstrasi di Kelas IV SD

The problem of how an increase in research activities of students in learning science by using the method of demonstration in class IV Unit Chief Gurung SDN 12 Kapuas Hulu. The general objective of the study to describe an increase in the activity of the students in learning science by applying the method of demonstration. Research procedures include the planning, implementation, observation and reflection. Data collection techniques used observation techniques and measurement techniques. Means of collecting data observation sheet. Based on observations, it is known that there is an increase in physical activity from baseline of 36% to 94% the second cycle of 58% with a high enough category, there is an increase in mental activity of learners from baseline 13.33% to 78.34% for the second cycle 65 , 01% with "high", and there is increased activity of learner emotional baseline 38.33% to 88.34% for the second cycle of 50.01% to the category of "high enough". It can be concluded that the application of the method of demonstration in learning science can enhance the activity of the fourth grade students of SDN 12 Unit Chief Gurung Kapuas Hulu

Transient Flow and Pigging Operation in Gas-Liquid Two Phase Pipelines

For simulation of transient gas-liquid two phase flow, the continuity, momentum and energy equations for two fluids should be solved, which requires complex calculations. In oil and gas pipelines, it is possible to perform some simplifications on continuity and momentum equations. This will be done by using quasi steady state assumption for gas continuity equation and also local equilibrium momentum balance for both phases in some flow patterns such as stratified, annular, slug and bubbly flows. In this paper, simplified transient simulation with assumption of isothermal flow was utilized together with flow patterns transition criterion and tested against experimental data for verification of the results. For this purpose, a computer code was written and implemented as transient flow simulator. In this code, the one dimensional differential equations were discretized by semi- implicit finite difference method and solved by an iterative manner. Also, a model for pigging operation was developed to analyze the flow parameters in pipeline during and after pigging. The numerical results were compared with the experimental data and it is observed that agreement with experimental data is satisfactory from practical engineering stand point

Effects of Continuous Care Model on Blood Pressure in Patients with Type II Diabetes

Introduction: One of the main problems encountered by type II diabetes patients is high Blood Pressure (BP). Continuous care is the standard process of making effective, mutual, and continuous relationships between patients and nurses as healthcare providers. Continuous Care Model (CCM) can help the nurses in identifying needs, problems, and sensitisations of the patients and encourage them to maintain and enhance their health status. Aim: This study aimed to investigate the effects of CCM on the BP trends of patients with type II diabetes in llam city. Materials and Methods: This quasi - experimental research was conducted in 80 patients with type II diabetes. Subjects were selected using cluster sampling method and then were randomly divided into intervention and control groups. Interventions based on the CCM were in the form of training sessions that were conducted for three weeks. Consequently, continuous care consultations, control, and assessment were conducted for nine weeks. A questionnaire on demographic characteristics and a BP recording device was used to collect the data obtained before intervention and 1-3 months after intervention. Then, descriptive and inferential tests (ANOVA, repeated measures, chi-square) were used for data analysis. Results: Findings revealed that the mean BP (measured in mmHg) scores of the CCM (systolic, 133.22 +/- 3.98; diastolic, 86.00 +/- 2.96) and control groups (systolic, 133.65 +/- 2.10; diastolic 84.62 +/- 2.72) before intervention were not significant (p>0.05); however, after intervention, a significant difference was observed between the mean BP (measured in mmHg) scores of the CCM (systolic, 127.52 +/- 3.13; diastolic, 80.75 +/- 1.97) and control groups (systolic, 133.65 +/- 2.25; diastolic, 83.87 +/- 2.12) (p<0.05). Conclusion: CCM is suggested to be effective in managing the BP and can be applied to improve the health behaviour in patients with type II diabetes