3,283 research outputs found

    Civilization and the evolution of short sighted agents

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    We model an assurance game played within a population with two types of individuals -- short-sighted and foresighted. Foresighted people have a lower discount rate than short sighted people. These phenotypes interact with each other. We define the persistent interaction of foresighted people with other foresighted people as a critical element of civilization while the interaction of short sighted people with other short sighted people as critical to the failure of civilization. We show that whether the short sighted phenotype will be an evolutionary stable strategy (and thus lead to the collapse of civilization) depends on the initial proportion of short sighted people relative to people with foresight as well as their relative discount rates. Further we explore some comparative static results that connect the probability of the game continuing and the relative size of the two discount rates to the likelihood that civilization will collapse.society; breakdown; evolution; replicator; dynamic; process; civilization; conflict; institution

    Advances in quantum machine learning

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    Here we discuss advances in the field of quantum machine learning. The following document offers a hybrid discussion; both reviewing the field as it is currently, and suggesting directions for further research. We include both algorithms and experimental implementations in the discussion. The field's outlook is generally positive, showing significant promise. However, we believe there are appreciable hurdles to overcome before one can claim that it is a primary application of quantum computation.Comment: 38 pages, 17 Figure

    Smart thermostat

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    The current thermostat marketplace is dominated by programmable thermostats that are engineered to give the user as much control as possible. However, not all users program these thermostats optimally. Some prefer comfort over energy efficiency and will heat an empty house. Others do not care to program their thermostat and leave it at a set temperature. The Smart Thermostat that we have created is engineered to optimize the temperature for the user, using the common sense of the engineer to lower energy consumption. It uses a Raspberry Pi as a platform to implement a fuzzy logic control System. By removing the extensive control of the thermostat from the user we are able to create a more energy efficient product that also maintains the comfort level of the occupants

    High Potential Middle Leaders (Secondary) programme: an evaluation

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    Health Technology Assessment (HTA) Case Studies : Factors Influencing Divergent HTA Reimbursement Recommendations in Australia, Canada, England, and Scotland

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    This document is the accepted manuscript version of the following article: Nicola Allen, Stuart R. Walker, Lawrence Liberti, and Sam Salek, ‘Health Technology Assessment (HTA) Case Studies: Factors Influencing Divergent HTA Reimbursement Recommendations in Australia, Canada, England, and Scotland’, Vol. 20 (3): 320-328, 2017, is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License CC BY NC-ND 4.0 ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The final, definitive version is available online at doi:https://doi.org/10.1016/j.jval.2016.10.014.OBJECTIVES: To evaluate the national regulatory, health technology assessment (HTA), and reimbursement pathways for public health care in Australia, Canada, England, and Scotland, to compare initial Canadian national HTA recommendations with the initial decisions of the other HTA agencies, and to identify factors for differing national HTA recommendations between the four HTA agencies. METHODS: Information from the public domain was used to develop a regulatory process map for each jurisdiction and to compare the HTA agencies' reimbursement recommendations. Medicines that were reviewed by all four agencies and received a negative recommendation from only one agency were selected as case studies. RESULTS: All four countries have a national HTA agency. Their reimbursement recommendations are guided by both clinical efficacy and cost-effectiveness, and the necessity for patient input. Their activities, however, vary because of different mandates and their unique political, social, and population needs. All have an implicit or explicit quality-adjusted life-year threshold. The seven divergent case studies demonstrate examples in which new medicine-indication pairs have been rejected because of uncertainties surrounding a range of factors including cost-effectiveness, comparator choice, clinical benefit, safety, trial design, and submission timing. CONCLUSIONS: The four HTA agencies selected for inclusion in this study share common factors, including a focus on clinical efficacy and cost-effectiveness in their decision-making processes. The differences in recommendations could be considered to be due to an individual agency's approach to risk perception, and the comparator choice used in clinical and cost-effectiveness studies.Peer reviewedFinal Accepted Versio
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