Chlamydia trachomatis Pgp3 antibody persists and correlates with self-reported infection and behavioural risks in a blinded cohort study

Chlamydia trachomatis (Ct) serological studies in populations could help monitor changes in lifetime cumulative risk of infection. We developed a double-antigen sandwich ELISA based on the Ct-specific Pgp3 antigen, then tested blind stored sera from over 800 participants in a New Zealand birth cohort from Dunedin at ages 26, 32 and 38. The double-antigen sandwich ELISA was more sensitive than our previously characterised indirect Pgp3 ELISA. Pgp3 antibody was detected more often in women compared to men and correlated with increasing numbers of sexual partners, self-reported Ct, and younger age at sexual debut in both women and men. At age 26, 24.1% (99/411) of women were Pgp3 seropositive, as were 79.5% (35/44) of those reporting Ct infection; Pgp3 antibody persisted to age 38 in 96.5% (83/86). In men at age 26, the figures were 10.7% (47/442) and 25.0% (6/24), respectively, with high (83.9%) antibody persistence to age 38. At age 38, among those Pgp3 seropositive, 63.3% of women and 83.1% of men had not reported Ct infection. Thus, Ct-specific Pgp3 antibody was detected in most women reporting Ct infection and correlated with risk of infection in those who did not, with most infections remaining undetected. As this antibody persisted for at least twelve years in 96% of these women, serology could be used to evaluate Ct prevention programmes among women

Compliance with labour rights and international labour standards: Implications for workplace productivity and competitiveness

The common perception, particularly among employers of labour is that enforcement or implementation of enhanced labour standards would negatively impact on overhead costs thereby impeding the organisation’s competitive advantage through price mechanisms at both national and global marketplace. The purpose of this paper is to provide an analysis and draw inherent relationships between enforcement of labour standards by organisations and possible implications on workplace productivity and overall organisational efficiency, competitiveness and survival. Theorists of firm’s wage efficiency argue that implementation of enhanced labour standards will most certainly increase overhead costs and push up prices thereby disadvantaging the firm’s ability from competing favourably with other firm’s operating in territories where labour standards are not observed. However, comparative cost-benefit analysis of implementing labour standards by this paper suggests that organisations indeed benefit significantly by enforcing labour standards as this would translate to higher productivity and enhanced organisational competitiveness and survival as workers experience job satisfaction, safe and healthy working conditions and environment which reduces rate of industrial accidents, medical costs and sick leaves. Furthermore, employers benefit from implementing enhanced labour standards through low employee turnover rate and improved cooperation and understanding between workers and their employers resulting in a stable and positive labour relations environment that is devoid of unplanned work stoppages due to industrial actions and loss of production.KIM201

Pursuing Gravitational S-Duality

Recently a strong-weak coupling duality in non-abelian non-supersymmetric theories in four dimensions has been found. An analogous procedure is reviewed, which allows to find the `dual action' to the gauge theory of dynamical gravity constructed by the MacDowell-Mansouri model plus the superposition of a $\Theta$ term.Comment: Invited paper to appear in the special issue of the `Journal of Chaos, Solitons and Fractals' on: "Superstrings, M,F,S,... Theory" (M.S. El Naschie and C. Castro, editors), 19 pages, LaTeX file, no figure

N-String Vertices in String Field Theory

We give the general form of the vertex corresponding to the interaction of an arbitrary number of strings. The technique employed relies on the ``comma" representation of String Field Theory where string fields and interactions are represented as matrices and operations between them such as multiplication and trace. The general formulation presented here shows that the interaction vertex of N strings, for any arbitrary N, is given as a function of particular combinations of matrices corresponding to the change of representation between the full string and the half string degrees of freedom.Comment: 22 pages, A4-Latex (latex twice), FTUV IFI

Towards a Gravitational Analog to S-duality in Non-abelian Gauge Theories

For non-abelian non-supersymmetric gauge theories, generic dual theories have been constructed. In these theories the couplings appear inverted. However, they do not possess a Yang-Mills structure but rather are a kind of non-linear sigma model. It is shown that for a topological gravitational model an analog to this duality exists.Comment: LaTeX, 14 pages, no figures, minor correction

Revisiting employee motivation and job satisfaction within the context of an emerging economy: Theoretical representation and developing the model

The world’s economic attention is rapidly shifting towards the direction of emerging economies. In order to facilitate and accelerate this process, it is important that designated economic hubs are well positioned in terms of infrastructural and social development. This can only be achieved through an integrated human resource practices that recognises the importance of human beings (employees) as the most important factor for the success or failure of any social or economic project. This imperative therefore places employee motivation and job satisfaction in the forefront. It was against this background that this research was conducted to determine the level at which municipal employees of one of the world-class socio-economic cities in South Africa enjoyed job satisfaction using selected motivational variables. The study adopted a survey research method using quantitative research design. A measuring instrument with a Cronbach alpha coefficient of above 0.70 was developed and used to collect primary data from 300 employees of the municipal council. Main hypotheses were formulated and tested using both regression and correlation statistical analyses. Results show that intrinsic and extrinsic motivational variables impacted significantly on the level at which employees derived job satisfaction. Management can therefore develop a job satisfaction practice around identified motivational variables in order to maximise employee productivity and enhance quality service delivery.KIM201

1+1 dimensional QCD with fundamental bosons and fermions

We analyze the properties of mesons in 1+1 dimensional QCD with bosonic and fermionic ``quarks'' in the large \nc limit. We study the spectrum in detail and show that it is impossible to obtain massless mesons including boson constituents in this model. We quantitatively show how the QCD mass inequality is realized in two dimensional QCD. We find that the mass inequality is close to being an equality even when the quarks are light. Methods for obtaining the properties of ``mesons'' formed from boson and/or fermion constituents are formulated in an explicit manner convenient for further study. We also analyze how the physical properties of the mesons such as confinement and asymptotic freedom are realized.Comment: 20 pages, harvmac, 5 figure

Human immunodeficiency virus (HIV) specific antibodies among married pregnant women and female commercial sex workers attending voluntary counseling and HIV testing (VCT) centre in Abuja, Nigeria

Generally, married women and commercial sex workers (CSWs) engage in sexual activity - an important risk factor for contracting HIV. We therefore tested a hypothesis that prevalence of HIV-1/2 antibodiesamong married pregnant women (PW) is not different from that of female CSWs. One hundred married PW and 99 female CSWs enrolled in the study. They were consecutively selected as they visited the VCT centre for HIV antibody test. Pertinent data were obtained from each subject using questionnaire forms; venous blood sample was aseptically collected from subjects that gave verbal consent. Plasmaobtained from each sample was tested using parallel testing algorithm with DETERMINE® HIV-1/2 and HIV-1/2 STAT-PAK® test was used for statistical analysis of the data. The overall prevalence of HIV-1/2antibodies was 29.1% (n = 199). Seroprevalence of 39.4 and 19.0% were observed for the CSWs and the PW, respectively. Using various variables, comparison of HIV-1/2 serostatus of the CSWs with that ofthe married PW showed that the CSWs generally had significantly higher seroprevalence. CSWs who were inconsistent in the use of condom with their clients prior to sexual intercourse in the past three months before this study (P = 0.0001, OR = 11.2) and those aged 39 years had significantly (P = 0.004, OR = 2.6) higher seroprevalence. Though both groups recorded seropositivity, inconsistency in the useof condom appeared to be the factor mostly responsible for the significantly higher seropositivity of the female CSWs

UK experience of liver transplantation for erythropoietic protoporphyria

Erythropoietic protoporphyria (EPP) is characterised by excess production of free protoporphyrin from the bone marrow, most commonly due to deficiency of the enzyme ferrochelatase. Excess protoporphyrin gives rise to the cutaneous photosensitivity characteristic of the disease, and in a minority of patients leads to end-stage liver disease necessitating liver transplantation (LT). There is limited information regarding the timing, impact and long-term outcome of LT in such patients, thus we aimed to identify the indications and outcomes of all transplants performed for EPP in the UK using data from the UK Transplant Registry. Between 1987 and 2009, five patients underwent LT for EPP liver disease. Median follow-up was 60 months, and there were two deaths at 44 and 95 months from causes unrelated to liver disease. The remaining recipients are alive at 22.4 years, 61 months and 55 months after transplant. A high rate of postoperative biliary stricturing requiring multiple biliary interventions was observed. Recurrent EPP-liver disease occurred in 4/5 (80%) of patients but graft failure has not been observed. Given the role of biliary obstruction in inducing EPP-mediated liver damage, we suggest that consideration should be given for construction of a Roux loop at the time of transplant. Thus we demonstrate that although EPP liver transplant recipients have a good long-term survival, comparable to patients undergoing LT for other indications, biliary complications and disease recurrence are almost universal, and bone marrow transplantation should be considered where possible

Maxillofacial and mandibular phenotypes in the skulls of red Sokoto and Sahel goats in Nigeria: The role of dental abnormalities

This work examined phenotypic expressions in the anatomy of the mandible and maxillofacial region of the Red Sokoto and Sahel goats in Nigeria. The infraorbital foramen was placed above premolar two (PM2) in Red Sokoto but above premolar one (PM1) in Sahel. The Red Sokoto displayed interdigital septa (ruggae) which entered into mediolateral depressions of the opposing mandible but this was less prominent in the Sahel. Dental abnormalities were more pronounced in the Red Sokoto on the maxilla and mandibular rows. The facial and mandibular tuberosities were more prominent in the Red Sokoto goat and found to be more conspicuous in this breed with dental abnormalities. There was no significant difference between Calcium and Phosphorus in the craniofacial bones of goats with dental abnormalities compared to those without dental abnormalities in both breeds and in conclusion we thus suggest that the harsh environmental conditions of arid North West may be a greater predisposing factor for the negative dental profile of the Red Sokoto breed