Space education in Kiruna, Northern Sweden

The town of Kiruna in the north of Sweden has a concentration of space activities and space research with, for example, the Swedish Institute of Space Physics, Esrange, the ESA Salmijärvi satellite station, and EISCAT (European Incoherent Scatter Radar) Scientific Association. The Department of Space Science is a joint department between the two most northern universities in Sweden, Luleå University of Technology and Umeå University in collaboration with the Swedish Institute of Space Physics. It offers a range of education programmes in the space field. There are bachelor and master programmes in space engineering, and a bridging programme for students without a science background from secondary school. The Department also contributes to courses for teachers, Ph.D. courses and secondary school level courses. One master´s program and a three week summer course are given entirely in English and welcome international students. Thanks to good cooperation with Esrange students can build and fly experiments on high altitude balloons and sounding rockets and also take a large responsibility for the management of the projects. Close interaction with research and industry is an important part of the education

Bob Flanagan: Taking It Like a Man

Bob Flanagan: Taking It Like a Ma

Disability and Comic Violence in There's Something About Mary

Produced by The Center on Disability Studies, University of Hawai'i at Manoa, Honolulu, Hawai'i and The School of Social Studies, The University of Texas at Dallas, Richardson, Texas for The Society for Disability Studies

Space education in Kiruna, Northern Sweden

International audienceThe town of Kiruna in the north of Sweden has a concentration of space activities and space research with, for example, the Swedish Institute of Space Physics, Esrange, the ESA Salmijärvi satellite station, and EISCAT (European Incoherent Scatter Radar) Scientific Association. The Department of Space Science is a joint department between the two most northern universities in Sweden, Luleå University of Technology and Umeå University in collaboration with the Swedish Institute of Space Physics. It offers a range of education programmes in the space field. There are bachelor and master programmes in space engineering, and a bridging programme for students without a science background from secondary school. The Department also contributes to courses for teachers, Ph.D. courses and secondary school level courses. One master´s program and a three week summer course are given entirely in English and welcome international students. Thanks to good cooperation with Esrange students can build and fly experiments on high altitude balloons and sounding rockets and also take a large responsibility for the management of the projects. Close interaction with research and industry is an important part of the education

Considering Disability: Disability Phenomenology's Role in Revolutionizing Theatrical Space

Considering Disability: Disability Phenomenology's Role in Revolutionizing Theatrical Spac

The Zero-Lift Drag of Several Configurations of the XAAM-N-2 Pilotless Aircraft. TED No. NACA DE332

Free-flight tests have been made to determine the zero-lift drag of several configurations of the XAAM-N-2 pilotless aircraft. Base-pressure measurements were also obtained for some of the configurations. The results show that increasing the wing-thickness ratio from 4 to 6 percent increased the wing drag by about 100 percent at M = 1.3 and by about 30 percent at M = 1.8. Increasing the nose fineness ratio from 5.00 to 6.25 reduced the drag coefficient of the wingless models a maximum of about 0.030 (10 percent) at M = 2.0. A corresponding change in nose shape for the winged models decreased the drag coefficient by about 0.05 in the Mach number range from 1.1 to 1.4; at Mach numbers greater than 1.6 no measurable reduction in drag coefficient was obtained. The drag of the present Sparrow fuselage is less than that of a parabolic fuselage which could contain the same equipment

Adsorption and Reduction of NO on Tin(W)Oxide Doped with Chromium(lll) Oxide

Functional Reactive Programming (FRP) is claimed to be a good choice for event handling applications. Current object- oriented telecom applications are known to suffer from additional complexity due to event handling code. In this paper we study the maintainability of FRP programs in the tele- com domain compared to traditional object-oriented programming (OOP), with the motivation that higher maintainability increases the service quality and decreases the costs. Two implementations of the same procedure are created: one using Haskell and the reactive-banana FRP frame- work and one using C++ and the OOP paradigm. Four software experts each with over 20 years of experience and three development engineers working on a product subject to study were engaged in evaluations, based on a questionnaire involving five different aspects of maintainability. The evaluations indicate a higher maintainability profile for FRP compared with OOP. This is confirmed by a more detailed analysis of the code size. While performance was not a main criteria, a preliminary evaluation shows that the OOP prototype is 8-10 times faster than the FRP prototype in the current (non-optimised) implementations.Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or re-publish, to post on servers or to redistribute to lists, requires prior specific permissionand/or a fee. Request permissions from [email protected].</p

Praxis: An Editorial Statement

Praxis: An Editorial Statemen

Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy

Background. One of the major challenges affecting sarcoma treatment outcome, particularly that of metastatic disease, is resistance to chemotherapy. Cancer-initiating cells are considered a major contributor to this resistance. Methods. An immortalised nontransformed human stromal (mesenchymal) stem cell line hMSC-TERT4 and a transformed cell line hMSC-TERT20-CE8, known to form sarcoma-like tumours when implanted in immune-deficient mice, were used as models. Receptor tyrosine kinase (RTK) activation was analysed by RTK arrays and cellular viability after tyrosine kinases inhibitor (TKI) treatment with or without doxorubicin was assessed by MTS assay. Results. Initial results showed that the hMSC-TERT4 was more doxorubicin-sensitive while hMSC-TERT20-CE8 was less doxorubicin-sensitive evidenced by monitoring cell viability in the presence of doxorubicin at different doses. The epidermal growth factor receptor (EGFR) was activated in both cell lines. However hMSC-TERT20-CE8 exhibited significantly higher expression of the EGFR ligands. EGFR inhibitors such as erlotinib and afatinib alone or in combination with doxorubicin failed to further decrease cell viability of hMSC-TERT20-CE8. However, inhibition with the TKI dasatinib in combination with doxorubicin decreased cell viability of the hMSC-TERT20-CE8 cell line. Conclusion. Our results demonstrate that dasatinib, but not EGFR-directed treatment, can decrease cell viability of stromal cancer stem cells less sensitive to doxorubicin

Effect of acute copper sulfate exposure on olfactory responses to amino acids and pheromones in goldfish (Carassius auratus)

Exposure of olfactory epithelium to environmentally relevant concentrations of copper disrupts olfaction in fish. To examine the dynamics of recovery at both functional and morphological levels after acute copper exposure, unilateral exposure of goldfish olfactory epithelia to 100 μM CuSO4 (10 min) was followed by electro-olfactogram (EOG) recording and scanning electron microscopy. Sensitivity to amino acids (L-arginine and L-serine), generally considered food-related odorants, recovered most rapidly (three days), followed by that to catecholamines(3-O-methoxytyramine),bileacids(taurolithocholic acid) and the steroid pheromone, 17,20 -dihydroxy-4-pregnen- 3-one 20-sulfate, which took 28 days to reach full recovery. Sensitivity to the postovulatory pheromone prostaglandin F2R had not fully recovered even at 28 days. These changes in sensitivity were correlated with changes in the recovery of ciliated and microvillous receptor cell types. Microvillous cells appeared largely unaffected by CuSO4 treatment. Cilia in ciliated receptor neurones, however, appeared damaged one day post-treatment and were virtually absent after three days but had begun to recover after 14 days. Together, these results support the hypothesis that microvillous receptor neurones detect amino acids whereas ciliated receptor neurones were not functional and are responsible for detection of social stimuli (bile acidsandpheromones).Furthermore, differences in sensitivity to copper may be due to different transduction pathways in the different cell types