Every Child Matters? An Evaluation of "Special Educational Needs" Programmes in England

The need for education to help every child rather than focus on average attainment has become a more central part of the policy agenda in the US and the UK. Remedial programmes are often difficult to evaluate because participation is usually based on pupil characteristics that are largely unobservable to the analyst. In this paper we evaluate programmes for children with moderate levels of 'special educational needs' in England. We show that the decentralized design of the policy generates significant variations in access to remediation resources across children with similar prior levels of difficulty. However, this differential is not reflected in subsequent educational attainment – suggesting that the programme is ineffective for 'treated' children. In the second part of our analysis, we use demographic variation within schools to consider the effect of the programme on whole year groups. Our analysis is consistent with no overall effect on account of the combined direct and indirect (spillover) effects. Thus, the analysis suggests that a key way that English education purports to help children with learning difficulties is not working.education, special needs, evaluation

Shear-induced transitions and instabilities in surfactant wormlike micelles

In this review, we report recent developments on the shear-induced transitions and instabilities found in surfactant wormlike micelles. The survey focuses on the non-linear shear rheology and covers a broad range of surfactant concentrations, from the dilute to the liquid-crystalline states and including the semi-dilute and concentrated regimes. Based on a systematic analysis of many surfactant systems, the present approach aims to identify the essential features of the transitions. It is suggested that these features define classes of behaviors. The review describes three types of transitions and/or instabilities : the shear-thickening found in the dilute regime, the shear-banding which is linked in some systems to the isotropic-to-nematic transition, and the flow-aligning and tumbling instabilities characteristic of nematic structures. In these three classes of behaviors, the shear-induced transitions are the result of a coupling between the internal structure of the fluid and the flow, resulting in a new mesoscopic organization under shear. This survey finally highlights the potential use of wormlike micelles as model systems for complex fluids and for applications.Comment: 64 pages, 31 figures, 2 table

An Evaluation of “Special Educational Needs” Programmes in England

The need for education to help every child rather than focus on average attainment has become a more central part of the policy agenda in the US and the UK. Remedial programmes are often difficult to evaluate because participation is usually based on pupil characteristics that are largely unobservable to the analyst. In this paper we evaluate programmes for children with moderate levels of 'special educational needs' in England. We show that the decentralized design of the policy generates significant variations in access to remediation resources across children with similar prior levels of difficulty. However, this differential is not reflected in subsequent educational attainment - suggesting that the programme is ineffective for 'treated' children. In the second part of our analysis, we use demographic variation within schools to consider the effect of the programme on whole year groups. Our analysis is consistent with no overall effect on account of the combined direct and indirect (spillover) effects. Thus, the analysis suggests that a key way that English education purports to help children with learning difficulties is not working.education, special needs, evaluation,

Magnetic fields on young, moderately rotating Sun-like stars - I: HD~35296 and HD~29615

Observations of the magnetic fields of young solar-type stars provide a way to investigate the signatures of their magnetic activity and dynamos. Spectropolarimetry enables the study of these stellar magnetic fields and was thus employed at the T\'{e}lescope Bernard Lyot and the Anglo-Australian Telescope to investigate two moderately rotating young Sun-like stars, namely HD 35296 (V119 Tau, HIP 25278) and HD 29615 (HIP 21632). The results indicate that both stars display rotational variation in chromospheric indices consistent with their spot activity, with variations indicating a probable long-term cyclic period for HD 35296. Additionally, both stars have complex, and evolving, large-scale surface magnetic fields with a significant toroidal component. High levels of surface differential rotation were measured for both stars. For the F8V star HD 35296 a rotational shear of $\Delta\Omega$ = 0.22$^{+0.04}_{-0.02}$ rad/d was derived from the observed magnetic profiles. For the G3V star HD 29615 the magnetic features indicate a rotational shear of $\Delta\Omega$ = 0.48$_{-0.12}^{+0.11}$ rad/d, while the spot features, with a distinctive polar spot, provide a much lower value of $\Delta\Omega$ of 0.07$_{-0.03}^{+0.10}$ rad/d. Such a significant discrepancy in shear values between spot and magnetic features for HD 29615 is an extreme example of the variation observed for other lower-mass stars. From the extensive and persistent azimuthal field observed for both targets it is concluded that a distributed dynamo operates in these moderately rotating Sun-like stars, in marked contrast to the Sun's interface-layer dynamo.Comment: 18 Pages, 13 figures, 5 tables, accepted for publication in MNRA

Deuterium Fractionation: the Ariadne's Thread from the Pre-collapse Phase to Meteorites and Comets today

The Solar System formed about 4.6 billion years ago from a condensation of matter inside a molecular cloud. Trying to reconstruct what happened is the goal of this chapter. For that, we put together our understanding of Galactic objects that will eventually form new suns and planetary systems, with our knowledge on comets, meteorites and small bodies of the Solar System today. Our specific tool is the molecular deuteration, namely the amount of deuterium with respect to hydrogen in molecules. This is the Ariadne's thread that helps us to find the way out from a labyrinth of possible histories of our Solar System. The chapter reviews the observations and theories of the deuterium fractionation in pre-stellar cores, protostars, protoplanetary disks, comets, interplanetary dust particles and meteorites and links them together trying to build up a coherent picture of the history of the Solar System formation. We emphasise the interdisciplinary nature of the chapter, which gathers together researchers from different communities with the common goal of understanding the Solar System history.Comment: Accepted for publication as a chapter in Protostars and Planets VI, University of Arizona Press (2014), eds. H. Beuther, R. Klessen, C. Dullemond, Th. Hennin

Local Clustering of Transferrin Receptors Promotes Clathrin-Coated Pit Initiation

Clathrin-mediated endocytosis (CME) is the major pathway for concentrative uptake of receptors and receptor–ligand complexes (cargo). Although constitutively internalized cargos are known to accumulate into maturing clathrin-coated pits (CCPs), whether and how cargo recruitment affects the initiation and maturation of CCPs is not fully understood. Previous studies have addressed these issues by analyzing the global effects of receptor overexpression on CME or CCP dynamics. Here, we exploit a refined approach using expression of a biotinylated transferrin receptor (bTfnR) and controlling its local clustering using mono- or multivalent streptavidin. We show that local clustering of bTfnR increased CCP initiation. By tracking cargo loading in individual CCPs, we found that bTfnR clustering preceded clathrin assembly and confirmed that bTfnR-containing CCPs mature more efficiently than bTfnR-free CCPs. Although neither the clustering nor the related changes in cargo loading altered the rate of CCP maturation, bTfnR-containing CCPs exhibited significantly longer lifetimes than other CCPs within the same cell. Together these results demonstrate that cargo composition is a key source of the differential dynamics of CCPs

Avances en la comprensión de la transición forestal en fincas costarricenses

Este estudio evaluó cuales factores han influido la adopción de prácticas de conservación y aumento de la Cobertura Arbórea en Fincas (CAF) en tres zonas rurales de Costa Rica. Se complementó información de censos poblacionales y datos geo-espaciales con resultados de entrevistas y talleres con 163 productores, aplicando un enfoque de indagación apreciativa y el marco de capitales de la comunidad. Los resultados confirman que también utilizando indicadores de desarrollo basado en estos enfoques y trabajando con CAF en paisajes agrícolas, es válida la teoría de la transición forestal (Mather 1992). Además se sugiere que si el proceso de desarrollo pone mayor énfasis en fortalecer el capital social (capacidad de organización, intercambio de información) y humano (salud, educación, asistencia técnica), existirá mayor probabilidad que el desarrollo irá acompañado por un proceso de recuperación de la CAF. La combinación de estos factores surtió un mayor efecto sobre la CAF que la Ley Forestal de 1996 y su programa de pago por servicios ambientales (PSA).This study proposed to evaluate which factors have influenced the adoption of conservation practices and the increase of On-farm Tree Cover (OTC) in three areas of Costa Rica. We compared information from population census and geospatial data with results of interviews and workshops with 163 producers, applying the approaches of appreciative inquiry and the community capitals framework. The results confirm that using development indicators based on these approaches and working with OTC within agricultural landscapes, the Forest Transition theory (Mather 1992) also applies. In addition, our results suggest that when the development process emphasizes the strengthening of social (organizational capacity, sharing of information) and human capital (health, education, technical assistance), there is more probability that development will be accompanied by a process of recovery of the OTC in agricultural landscapes. The combination of these factors had greater effect on OTC than the Forest Law of 1996 with its payment for environmental services scheme

Reflections on the Cost of Low-Cost Whole Genome Sequencing: Framing the Health Policy Debate

The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us about potential benefits and harms, particularly in the context of health care policy. The scale and pace of adoption of this powerful new technology should be driven by clinical need, clinical evidence, and a commitment to put patients at the centre of health care policy

A new self-expanding aortic stent valve with annular fixation: in vitro haemodynamic assessment

Objective: Balloon-expandable stent valves require flow reduction during implantation (rapid pacing). The present study was designed to compare a self-expanding stent valve with annular fixation versus a balloon-expandable stent valve. Methods: Implantation of a new self-expanding stent valve with annular fixation (Symetis®, Lausanne, Switzerland) was assessed versus balloon-expandable stent valve, in a modified Dynatek Dalta® pulse duplicator (sealed port access to the ventricle for transapical route simulation), interfaced with a computer for digital readout, carrying a 25 mm porcine aortic valve. The cardiovascular simulator was programmed to mimic an elderly woman with aortic stenosis: 120/85 mmHg aortic pressure, 60 strokes/min (66.5 ml), 35% systole (2.8 l/min). Results: A total of 450 cardiac cycles was analysed. Stepwise expansion of the self-expanding stent valve with annular fixation (balloon-expandable stent valve) resulted in systolic ventricular increase from 120 to 121 mmHg (126 to 830 ± 76 mmHg)*, and left ventricular outflow obstruction with mean transvalvular gradient of 11 ± 1.5 mmHg (366 ± 202 mmHg)*, systolic aortic pressure dropped distal to the valve from 121 to 64.5 ± 2 mmHg (123 to 55 ± 30 mmHg) N.S., and output collapsed to 1.9 ± 0.06 l/min (0.71 ± 0.37 l/min* (before complete obstruction)). No valve migration occurred in either group. (* = p < 0.05). Conclusions: Implantation of this new self-expanding stent valve with annular fixation has little impact on haemodynamics and has the potential for working heart implantation in vivo. Flow reduction (rapid pacing) is not necessar