In trincea con gli antichi. Ricordi dei classici nei diari e nelle testimonianze della Grande Guerra

Abstrac

Tendencias de mortalidade por câncer de estômago no Brasil entre 1996 e 2006

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Saúde Pública

Impacto do exercício físico de alta intensidade sobre a função endotelial em pacientes após infarto agudo do miocárdio.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Clínica Médica

Determinação do intervalo pr em 50 recém-nascidos normais de zero a 72 horas de vida.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis, 198

Avaliação da qualidade de vida dos pacientes com derivação urinária por cistectomia radical.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis, 200

Cyanobacteria vs green algae:which group has the edge?

The dogma surrounding carbon assimilation has it that, due to their highly effective CO2-concentrating mechanisms, cyanobacteria will always out-perform, for example, green algae where inorganic carbon is in short supply. Working on the cyanobacterial genus Microcystis, Ji et al. (2017) now suggest this might not always be true, with possible improved performance with rises in atmospheric (and hence dissolved) CO2. Many cyanobacteria form extensive toxic blooms that present significant health risks and economic costs: how they will react in a future world with elevated CO2 and temperature is thus of intense interest for water management

Effect of acute and repeated administration of paracetamol on opioidergic and serotonergic systems in rats.

Objective and design: We investigated the antinociceptiveeffect of paracetamol or morphine after repeatedadministration and the changes in the characteristics of centralμ-, κ- and 5-HT2 receptors.Treatment: Male rats were injected twice a day for sevendays with paracetamol (400 mg/kg, i. p.) or morphine (5 mg/kg, s. c.).Methods: The antinociceptive effect was evaluated 30 minafter single and multiple doses of paracetamol and morphinethrough the hot-plate test. Binding techniques were used toevaluate the receptor characteristics in the frontal cortex.Results: Both paracetamol and morphine induced an antinociceptiveeffect on day 1 but only paracetamol maintainedthis effect for seven days while morphine did not.The number of μ-opioid receptors decreased on days 1, 3,and 7 by a similar percentage after paracetamol administration(by 29, 31 and 34 %, respectively), while morphineproduced a progressive decrease in comparison with controls(by 37, 49 and 60 %, respectively) and κ-opioid receptorswere unaffected. Both drugs similarly decreased the 5-HT2receptor number on all days of treatment (by about 30 %).Conclusions: The opioidergic and serotonergic systems areinvolved in different ways in the induction and maintenanceof antinociception after paracetamol or morphine treatment

Non-invasive genetic approaches for estimation of ungulate population size: a study on roe deer (Capreolus capreolus) based on faeces

Estudios genéticos no invasivos, para la estimación del tamaño de una población de ungulados: estudio sobre el corzo (Capreolus capreolus) basado en sus heces La estimación de los tamaños de población es particularmente difícil en las especies de animales que viven en hábitats de vegetación densa, en la que se pueden mimetizar. Este es el caso del corzo, al igual que el de muchos otros ungulados. Nuestro objetivo fue desarrollar una aproximación genética no invasiva de captura–marcado–recaptura basada en las heces de corzo recogidas a lo largo de transectos. En un estudio piloto, recogimos 1.790 heces de corzo durante cinco días de muestreo en un área de estudio boscosa en el sudoeste de Alemania. Extrajimos el ADN de 410 de dichas muestras y llevamos a cabo un análisis de microsatélites utilizando siete marcadores de dinucleótidos. Los análisis tuvieron como resultado 328 genotipos consenso, que se asignaron a 174 individuos. La población estimada usando el enfoque bayesiano fue de 94 (82–111) machos y 136 (121–156) hembras. Nuestro estudio demuestra que los métodos genéticos no invasivos constituyen una herramienta de gestión muy valiosa para el corzo.Estudios genéticos no invasivos, para la estimación del tamaño de una población de ungulados: estudio sobre el corzo (Capreolus capreolus) basado en sus heces La estimación de los tamaños de población es particularmente difícil en las especies de animales que viven en hábitats de vegetación densa, en la que se pueden mimetizar. Este es el caso del corzo, al igual que el de muchos otros ungulados. Nuestro objetivo fue desarrollar una aproximación genética no invasiva de captura–marcado–recaptura basada en las heces de corzo recogidas a lo largo de transectos. En un estudio piloto, recogimos 1.790 heces de corzo durante cinco días de muestreo en un área de estudio boscosa en el sudoeste de Alemania. Extrajimos el ADN de 410 de dichas muestras y llevamos a cabo un análisis de microsatélites utilizando siete marcadores de dinucleótidos. Los análisis tuvieron como resultado 328 genotipos consenso, que se asignaron a 174 individuos. La población estimada usando el enfoque bayesiano fue de 94 (82–111) machos y 136 (121–156) hembras. Nuestro estudio demuestra que los métodos genéticos no invasivos constituyen una herramienta de gestión muy valiosa para el corzo.Estimating population size is particularly difficult for animal species living in concealing habitats with dense vegetation. This is the case for roe deer as for many other ungulates. Our objective was to develop a non–invasive genetic capture–mark–recapture approach based on roe deer faeces collected along transects. In a pilot study, we collected 1,790 roe deer faeces during five sampling days in a forested study area in south western Germany. We extracted DNA from 410 of these samples and carried out microsatellite analysis using seven dinucleotide markers. The analyses resulted in 328 useable consensus genotypes which were assigned to 174 individuals. The population size estimated using a Bayesian approach was 94 (82–111) male and 136 (121–156) female roe deer. Our study shows that non–invasive genetic methods are a valuable management tool for roe deer

Differential involvement of central 5-HT1B and 5-HT3 receptor subtypes in the antinociceptive effect of paracetamol

Objective: We investigated the effect of pre-treatment with ondansetron or CP 93129 (a 5-HT1B agonist) on the antinociceptive activity of paracetamol and the changes in central 5-HT3 receptors induced by paracetamol alone or co-administered with ondansetron. Materials and Subjects: Male Wistar rats (eight per group) were injected with ondansetron (2 and 4 mg/kg s. c.) or CP 93 129 (0.5, 1 and 2 mg/kg s. c.) 15 min before paracetamol (400 mg/kg, i.p.). Methods: Pain threshold was evaluated in the hot-plate or in the paw pressure test 30 min after the last treatment. 5-HT3 receptor binding capacity was measured in the frontal cortex, temporal-parietal cortex and midbrain by means of radioligand binding technique. Statistical analysis was done using ANOVA followed by Student-Newman-Keuls test and 2 X 2 factorial analysis when appropriate. Results: Pre-treatment with ondansetron, at doses of 2 and 4 mg/kg, did not affect the antinociceptive activity of paracetamol in the hot-plate test and in the paw pressure test. Paracetamol did not change the characteristics of 5-HT3 receptors in all the areas investigated. Ondansetron (4 mg/kg s. c) per se significantly increased the 5-HT3 receptor number in the areas used, the effect not being modified by co-administration with paracetamol. On the other hand, CP 93129 (2 mg/kg s. c.) significantly prevented the effect of paracetamol in both algesimetric tests used. Conclusions: Our data indicate that 5-HT1B but not 5-HT3 receptors are involved in the antinociceptive effect of paracetamol in our experimental conditions

The (Geometrical) dialogs Gehry establishes with the city of Bilbao

The shape of the Guggenheim Museum in Bilbao is problematized here with the didactic interest of investigating the design strategies used by Frank Gehry to reconfigure the urban fabric and landscape involved. There are few discourses about the design, accompanied by objective reasoning and supported by its formal decomposition. The convenience of this complementation is considered, given its potential as a reference in the architectural training process. We hypothesize that the shape of the building comes from a reduced repertoire of formal fragments within this fabric and landscape, configured both by classical composition rules and by fractal geometry. This interpretation, constructed by means of overlapping drawings to the photographic and technical images of the building and its immediate surroundings and by the concept of fractal dimension, facilitated the identification of strict formal control, which starts with the regulation of its representations in orthographic projection, maintaining proportions, parallelism and convergences; such as in perspective, exploring continuity achieved through anamorphic effects. Thus, we demonstrate the use of a method, of geometric approach, which facilitates the construction of hypotheses regarding design strategies. In this case, Gehry’s strategies to dialog with a particular urban fabric: through recursive actions, using topologic transformations, in its mathematical meaning, in the formal vocabulary of the place itself, actions today made easy through the digital means of representation