Pellolla viljeltävän non food -raaka-aineen saatavuus, laatu ja hyödyntäminen kemian teollisuuden tarpeisiin kriisitilanteissa. Tuotannon ja jalostuksen mahdollisuudet Suomessa

vokKirjasto Aj-kAvailability of cultured non food raw material, its quality and utilization for the needs of the chemical industry during a crisis. A study of the possibilities for production and processing in Finlan

From Resource to Burden: Rescaling Solidarity with Strangers in the Single Market

'Organised solidarity' of a mediated legal form constitutes the backbone of the modern welfare state built on solidarity between strangers. The interplay between the single market and the national social systems is key in defining who owes what to whom under the 'transnationalised' European solidarity. Free movement rights have increased the 'entanglement' of national social systems' revenue and expenditure sides, considered to jeopardise their steering capacity. As a corollary to free movement, transnational solidarity does not take place beyond or between national welfare states, but rather within: as solidarity with strangers. Here transnational solidarity is applied by way of a sociological framework to trace the evolutionary path of free movement of persons as it fluctuates between 'commodification' and 'decommodification'. Against that backdrop, this article reviews whether a paradigm shift is currently promoted as to the question where solidarity with strangers begins and ends

The Topological Sphere Theorem

Työssä esitellään todistuksineen klassinen pallolause, joka antaa leikkauskaarevuksien avulla riittävän ehdon kompaktin, yhdesti yhtenäisen Riemannin moniston homeomorfisuudelle euklidisen pallon kanssa. Todistus seuraa klassista Klingenbergin ja Bergerin todistusta, ja siinä merkittävä rooli on leikkauspisteillä - pisteillä, joiden jälkeen annetusta pisteestä lähtevät geodeesit eivät enää minimoi etäisyyksiä - ja moniston injektiivisyyssäteellä, joka on infimum moniston pisteiden ja niitä vastaavien leikkauspisteitten etäisyyksistä. Työssä esitellään tarvittavia Riemannin monistojen perusominaisuuksia, kuten metriikka, konnektiot ja kaarevuus, ja -tuloksia, esimerkiksi Rauchin vertailulause sekä Bonnet-Myersin lause. Pallolauseen ohella merkittäviä tuloksia työssä ovat Klingenbergin arvio moniston injektiivisyyssäteelle sekä Bergerin tulos minimoivien geodeesien jakautumisesta kompaktin moniston ääripisteiden välillä. Edellä mainitun tuloksen todistukseksi esitellään myös tarvittava määrä Morsen teoriaa, joka tutkii funktioiden kriittisten pisteiden vaikutusta määrittelyjoukkonsa topologiaan

Ethnobotanical Documentation of a Few Medicinal Plants in the Agasthiayamalai Region of Tirunelveli District, India

An ethnobotanical study of medicinal plants in Agasthiayamalai region of Tirunelveli district was done by collecting information from the experienced medicinal practitioners of Kani tribes. Ten plants were collected, authenticated and information on their medicinal uses along with the parts used and mode of administration is enumerated. The phytochemical constituents present in their extracted materials were identified. Antibacterial activity of the extracts was analysed and zone of inhibition for different bacterial strains is reported

Oppimista motivoiva moninaisuus : opettajien vinkkejä opettajille

Propongo seguir desustantivizando géneros y sexualidades, interrogando feminidades/masculinidades, desde los enclaves relacionales que proporcionan. Invito a seguir, reseguir, perseguir, tanto los ideales de coherencia, como las linealidades normativas con que se enredan conceptos/sujetos/prácticas. Así como investigar estas hilaturas liminares, que parecen invisibles e inocuas, pero que en realidad son constructos activos, tan políticamente institucionalizados, como todo aquello que son capaces de enredar. Propongo mirar invisibilidades y silencios, cuyos significados hace falta analizar, incluso desde incorrecciones políticas.I propose the continued ‘de-nominalizing’ of gender/sexuality, questioning femininities/masculinities, from the relational points that provides. I also encourage the following/reaching of both the ideals of coherence and the normative linealities that link concepts/subjects/practices. Also there is the need to research those places which are in between, which seem invisible and innocuous, but that really, are active constructions, both those that are politically institutionalized as well as all that can be included. I propose looking at the Invisibilities and the Silences, whose meanings need to be analyzed, to the politically incorrect

Negative Ion Positive Ion Coincidence Yields of Core Excited Water

We report yields of mass-resolved negative ions and positive ions measured in coincidence after core-excitation of water molecules. The analysis of negative-ion/positive-ion and negative-ion/positive-ion/positive-ion coincidence events provides new information on pathways leading to negative ion production, enhancing the present understanding of the dissociation processes of the water molecule. Dissociation following (resonant) Auger decay dominates negative ion production, but radiative decay is shown to contribute above the O 1s ionization threshold. A peak in the H-/O+ yield above the O 1s threshold is attributed to decay from doubly excited states

Valence photoionization of the N2 molecule in the region of the N 1s→Rydberg excitations

The intensities of the X and A valence photoelectron lines of N2 have been found to display Fano line shapes as a function of photon energy around the N 1s→ Rydberg excitations. The vibrational intensity distributions of these photoelectron lines change at the N 1s→3sσ and 3pπ resonances. These effects indicate interference between direct and resonant photoionization channels. Our numerical simulations reproduce quite well the experimental results

On the production of N-2(+) ions at the N 1s edge of the nitrogen molecule

The N+2 ion yield of the N2 molecule has been measured at the N 1s → Rydberg excitations. It displays Fano-type line shapes due to interference between direct outer-valence photoionization and participator decay of the core-excited Rydberg states. The N+2 ion yield is compared with the total intensity of the outer-valence photoelectron lines obtained recently with electron spectroscopy (Kivimäki et al 2012 Phys. Rev. A 86 012516). The increasing difference between the two curves at the higher core-to-Rydberg excitations is most likely due to soft x-ray emission processes that are followed by autoionization. The results also suggest that resonant Auger decay from the core–valence doubly excited states contributes to the N+2 ion yield at the photon energies that are located on both sides of the N 1s ionization limit

Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats

The aryl hydrocarbon receptor (AHR) mediates the toxicity of dioxins, but also plays important physiological roles. Selective AHR modulators, which elicit some effects imparted by this receptor without causing the marked toxicity of dioxins, are presently under intense scrutiny. Two novel such compounds are IMA-08401 (N-acetyl-N-phenyl-4-acetoxy-5-chloro-1,2-dihydro-1-methyl-2-oxo-quinoline-3-carboxamide) and IMA-07101 (N-acetyl-N-(4-trifluoromethylphenyl)-4-acetoxy-1,2-dihydro-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxamide). They represent, as diacetyl prodrugs, AHR-active metabolites of the drug compounds laquinimod and tasquinimod, respectively, which are intended for the treatment of autoimmune diseases and cancer. Here, we toxicologically assessed the novel compounds in Sprague-Dawley rats, after a single dose (8.75-92.5 mg/kg) and 5-day repeated dosing at the highest doses achievable (IMA-08401: 100 mg/kg/day; and IMA-07101: 75 mg/kg/day). There were no overt clinical signs of toxicity, but body weight gain was marginally retarded, and the treatments induced minimal hepatic extramedullary haematopoiesis. Further, both the absolute and relative weights of the thymus were significantly decreased. Cyp1a1 gene expression was substantially increased in all tissues examined. The hepatic induction profile of other AHR battery genes was distinct from that caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The only marked alterations in serum clinical chemistry variables were a reduction in triglycerides and an increase in 3-hydroxybutyrate. Liver and kidney retinol and retinyl palmitate concentrations were affected largely in the same manner as reported for TCDD. In vitro, the novel compounds activated CYP1A1 effectively in H4IIE cells. Altogether, these novel compounds appear to act as potent activators of the AHR, but lack some major characteristic toxicities of dioxins. They therefore represent promising new selective AHR modulators. (C) 2017 Elsevier Inc. All rights reserved.Peer reviewe

Evaluating oxidative stress, serological- and haematological status of dogs suffering from osteoarthritis, after supplementing their diet with fish or corn oil

Background: Oxidative stress plays an important role in the pathogenesis of disease, and the antioxidant physiological effect of omega-3 from fish oil may lead to improvement of canine spontaneous osteoarthritis (OA). Methods: In this prospective randomized, controlled, double-blinded study, we assessed haematological and biochemical parameters in dogs with OA following supplementation with either a concentrated omega-3 deep sea fish oil product or corn oil. Blood samples from 77 client-owned dogs diagnosed as having OA were taken before (baseline) and 16 weeks after having orally ingested 0.2 ml/Kg bodyweight/day of deep sea fish oil or corn oil. Circulating malondialdehyde (MDA), glutathione (GSH), non-transferrin bound iron (NTBI), free carnitine (Free-Car), 8-hydroxy-2-deoxyguanosine (8-OH-dG), and serum fatty acids, haemograms and serum biochemistry were evaluated. Differences within and between groups from baseline to end, were analysed using repeated samples T-test or Wilcoxon rank test and independent samples T-test or a Mann-Whitney test. Results: Supplementation with fish oil resulted in a significant reduction from day 0 to day 112 in MDA (from 3.41 +/- 1.34 to 2.43 +/- 0.92 mu mol/L; P <0.001) and an elevation in Free-Car (from 18.18 +/- 9.78 to 21.19 +/- 9.58 mu mol/L; P = 0.004) concentrations, whereas dogs receiving corn oil presented a reduction in MDA (from 3.41 +/- 1.34 to 2.41 +/- 1.01 mu mol/L; P = 0.001) and NTBI (from -1.25 +/- 2.17 to -2.31 +/- 1.64 mu mol/L; P = 0.002). Both groups showed increased (albeit not significantly) GSH and 8-OH-dG blood values. Dogs supplemented with fish oil had a significant reduction in the proportions of monocytes (from 3.84 +/- 2.50 to 1.77 +/- 1.92 %; P = 0.030) and basophils (from 1.47 +/- 1.22 to 0.62 +/- 0.62 %; P = 0.012), whereas a significant reduction in platelets counts (from 316.13 +/- 93.83 to 288.41 +/- 101.68 x 10(9)/L; P = 0.029), and an elevation in glucose (from 5.18 +/- 0.37 to 5.32 +/- 0.47 mmol/L; P = 0.041) and cholesterol (from 7.13 +/- 1.62 to 7.73 +/- 2.03 mmol/L; P = 0.011) measurements were observed in dogs receiving corn oil. Conclusions: In canine OA, supplementation with deep sea fish oil improved diverse markers of oxidative status in the dogs studied. As corn oil also contributed to the reduction in certain oxidative markers, albeit to a lesser degree, there was no clear difference between the two oil groups. No clinical, haematological or biochemical evidence of side effects emerged related to supplementation of either oil. Although a shift in blood fatty acid values was apparent due to the type of nutraceutical product given to the dogs, corn oil seems not to be a good placebo.Peer reviewe