UAS Literary & Arts Journal

Proof copy provided by Tidal Echoes.Tidal Echoes is an annual showcase of writers and artists with one thing in common: a life surrounded by the rainforests and waterways of Southeast Alaska.Davy Josh’s Note -- A Note from Chalise -- A Note from Emily Wall -- Brain Bucket -- Cephalic index -- A Gift of Fat for the Fire -- Our heroes have always been... -- Colorful Clouds -- Role Model -- Anchors -- Out My Window -- Adaptation -- Bookshelves -- In the Flow -- It’s a Small World Parade Float -- Sexy -- Death by Algebra -- Friend -- mirabile visu -- Exchange II -- F A D E -- Borne Alone -- Continuum -- The Week Before St. Valentine’s -- Bottled Up -- Untitled -- Early Morning Conspiracy Theory -- Westport -- Boulder Creek -- Jumping Off Rooftops -- Staying in the Room With Ernestine Hayes -- Blueberry -- After Neruda By Way of Bly (Tenure) -- Magic of Water -- Old Tom Steals the Light -- Old Tom Finds a Whale -- Research Project -- Guppy (boat) -- Arizona Spyder -- From Anthropomorphism to Zoomorphism -- Bus Stop -- December 1, 1955 -- Between Tides at Twilight -- Dementia -- Winter Ferry -- Coming into Auke Bay -- The Search for Jane Rogers -- Inlaid Tea Cups -- The Big Melt -- Kingsmill Reef -- Despite Man’s Best Efforts to Ruin It -- Roberts from Flume -- India Scarf -- Painted and Petrified -- Medicine Bag -- Merrill Field -- Deadly Kites -- Brazilian Ghetto -- Seattle Riff -- The Gospel Truth of My Gay Bird -- Signing the Divorce Papers -- Red Shades -- Holey Cow -- Untitled -- Series of Cedar Baskets -- A Conversation With Ranunculus -- Deconstruction -- Sandy Beach -- Threshold -- Oil and Honesty: An Interview with Artist and Professor David Woodie -- Mitkof #3 -- Still Life -- First Day of Fall -- Falling in the Garden -- After Finishing an Activities Report for the Dean -- Homage to Po Chü-I -- Nunc Dimittis -- Do Wise Men Have Bad Days? -- To the Plain Land -- Flood of ‘69 -- How a woman makes her own wine -- Untitled (translation from Russian) -- Existential Sestina -- It’s the knowing -- Blood and Guts -- Sometime Walking on the Beach -- Untitled -- Connecting the Pieces -- Hemlock -- Klawock Island -- Driven By the Tides -- Lunch -- The People -- Howling Dog -- Winter Cabin Lullaby -- Chain Gang -- A Review of Social Groups in Female Homo Sapiens as Exemplified by Mammary Restraint -- Apparatuses -- Douglas Island Bridge -- Going Home -- Author and Artist Biographie

The Effects of Mindful Movement and Exercise on Depression

This evidence based review looked at any correlation between aerobics, running, Qi\u27 gong and mindfulness practices like meditation and yoga. What were their effects if any on depression? The findings from meta-analysis concluded that each in their own way did in fact relieve, improve or prevent signs and symptoms of depression as well as other dysregulatory and co-occurring health concerns like PTSD, Anxiety, Chronic Pain, insomnia and addiction issues. There was a clear correlation that an integrative approach to treatments and therapies needs further research in conventional medicine. Some treatments were found to be as effective if not more so than pharmaceuticals. As health care costs continue to rise, alternative, complementary and integrative cost effective treatments and therapies should be researched and considered. This review helps open the door for policy makers and medical professionals to look at treatment modalities in their own professions

The Nurse's Role During The Childbirth Experience Of First-Time Fathers

The experience of first-time fathers during childbirth has changed dramatically over the last several decades. Recent studies have demonstrated that though the support person plays a major role in childbirth, they are often overlooked. Some first-time fathers may feel like they did not have many choices or a voice in the childbirth experience. This study analyzed the experiences of seven first-time fathers through personal interviews and is aimed at helping nurses adapt their care to better include fathers. These interviews identified a need for improved assessment of first-time fathers desired involvement in childbirth and ultimately leading to the development of an efficient tool to fill this gap.Nursin

Cathepsin K Deficiency Reduces Elastase Perfusion-Induced Abdominal Aortic Aneurysms in Mice

Objective: Cathepsin K (CatK) is one of the most potent mammalian elastases. We have previously shown increased expression of CatK in human abdominal aortic aneurysm (AAA) lesions. Whether this protease participates directly in AAA formation, however, remains unknown. Methods and Results: Mouse experimental AAA was induced with aortic perfusion of a porcine pancreatic elastase. Using this experimental model, we demonstrated that absence of CatK prevented AAA formation in mice 14 days postperfusion. CatK deficiency significantly reduced lesion CD4 T-cell content, total lesion and medial cell proliferation and apoptosis, medial smooth muscle cell (SMC) loss, elastinolytic CatL and CatS expression, and elastin fragmentation, but it did not affect AAA lesion Mac-3 macrophage accumulation or CD31 microvessel numbers. In vitro studies revealed that CatK contributed importantly to CD4 T-cell proliferation, SMC apoptosis, and other cysteinyl cathepsin and matrix metalloproteinase expression and activities in SMCs and endothelial cells but played negligible roles in microvessel growth and monocyte migration. AAA lesions from CatK-deficient mice showed reduced elastinolytic cathepsin activities compared with those from wild-type control mice. Conclusion: This study demonstrates that CatK plays an essential role in AAA formation by promoting T-cell proliferation, vascular SMC apoptosis, and elastin degradation and by affecting vascular cell protease expression and activities.Other Research Uni

A Natural Language Processing Pipeline for Detecting Informal Data References in Academic Literature

Discovering authoritative links between publications and the datasets that they use can be a labor-intensive process. We introduce a natural language processing pipeline that retrieves and reviews publications for informal references to research datasets, which complements the work of data librarians. We first describe the components of the pipeline and then apply it to expand an authoritative bibliography linking thousands of social science studies to the data-related publications in which they are used. The pipeline increases recall for literature to review for inclusion in data-related collections of publications and makes it possible to detect informal data references at scale. We contribute (1) a novel Named Entity Recognition (NER) model that reliably detects informal data references and (2) a dataset connecting items from social science literature with datasets they reference. Together, these contributions enable future work on data reference, data citation networks, and data reuse.Comment: 13 pages, 7 figures, 3 table

Mapping research topics at multiple levels of detail.

The institutional review of interdisciplinary bodies of research lacks methods to systematically produce higher-level abstractions. Abstraction methods, like the distant reading of corpora, are increasingly important for knowledge discovery in the sciences and humanities. We demonstrate how abstraction methods complement the metrics on which research reviews currently rely. We model cross-disciplinary topics of research publications and projects emerging at multiple levels of detail in the context of an institutional review of the Earth Research Institute (ERI) at the University of California at Santa Barbara. From these, we design science maps that reveal the latent thematic structure of ERIs interdisciplinary research and enable reviewers to read a body of research at multiple levels of detail. We find that our approach provides decision support and reveals trends that strengthen the institutional review process by exposing regions of thematic expertise, distributions and clusters of work, and the evolution of these aspects

A Guanidine-rich Regulatory Oligodeoxynucleotide Improves Type-2 Diabetes in Obese Mice by Blocking T-cell Differentiation

T lymphocytes exhibit pro-inflammatory or anti-inflammatory activities in obesity and diabetes, depending on their subtypes. Guanidine-rich immunosuppressive oligodeoxynucleotides (ODNs) effectively control Th1/Th2-cell counterbalance. This study reveals a non-toxic regulatory ODN (ODNR01) that inhibits Th1- and Th17-cell polarization by binding to STAT1/3/4 and blocking their phosphorylation without affecting Th2 and regulatory T cells. ODNR01 improves glucose tolerance and insulin sensitivity in both diet-induced obese (DIO) and genetically generated obese (ob/ob) mice. Mechanistic studies show that ODNR01 suppresses Th1- and Th17-cell differentiation in white adipose tissue, thereby reducing macrophage accumulation and M1 macrophage inflammatory molecule expression without affecting M2 macrophages. While ODNR01 shows no effect on diabetes in lymphocyte-free Rag1-deficient DIO mice, it enhances glucose tolerance and insulin sensitivity in CD4$^+$ T-cell-reconstituted Rag1-deficient DIO mice, suggesting its beneficial effect on insulin resistance is T-cell-dependent. Therefore, regulatory ODNR01 reduces obesity-associated insulin resistance through modulation of T-cell differentiation

DataChat: Prototyping a Conversational Agent for Dataset Search and Visualization

Data users need relevant context and research expertise to effectively search for and identify relevant datasets. Leading data providers, such as the Inter-university Consortium for Political and Social Research (ICPSR), offer standardized metadata and search tools to support data search. Metadata standards emphasize the machine-readability of data and its documentation. There are opportunities to enhance dataset search by improving users' ability to learn about, and make sense of, information about data. Prior research has shown that context and expertise are two main barriers users face in effectively searching for, evaluating, and deciding whether to reuse data. In this paper, we propose a novel chatbot-based search system, DataChat, that leverages a graph database and a large language model to provide novel ways for users to interact with and search for research data. DataChat complements data archives' and institutional repositories' ongoing efforts to curate, preserve, and share research data for reuse by making it easier for users to explore and learn about available research data.Comment: 6 pages, 2 figures, and 1 table. Accepted to the 86th Annual Meeting of the Association for Information Science & Technolog