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'Scoping interest in creating a publicly facing digital archive of women's activism in mental health in the UK': Report of workshop held in 2014 at the OU London.
This report published by the Open University gives a summary of the workshop held in June 2014 with OU research development funding to bring together 20 invited academics, policy makers, survivors/ service users, voluntary sector workers and practitioners to explore interest in creating publicly facing digital archive of testimonies about women's mental health activism in the UK since the 1970s
Functional Magnetic Resonance Imaging Studies of the Primary Somatosensory Cortex in Relation to Complex Regional Pain Syndrome
Functional MRI was used to detect brain activations in the primary somatosensory cortex (SI) in response to a vibrotactile stimulus applied to the thumb (D1) and little finger (D5) of the right (R) and left (L) hands. Four studies were carried out with healthy subjects in order to determine the scanning and stimulation protocols that resulted in consistent and robust SI activity. It was found that a strong stimulus, compared to a weak stimulus, led to the SI activity being detected more frequently and at a more statistically significant level. Also, extending the scanning duration per digit further increased the T-scores.
The SI activations for each digit showed multiple foci and were distributed throughout the SI area. However, a clustering occurred in separate centres for stimulation to RD1 and RD5 near the Brodmann area 1/Brodmann area 3 boundary. The Euclidean separations of the cortical digit representations for LD1-D5 and RD1-D5 were calculated on the basis of the `centre of mass' of the multiple activations. Observed separations ranged between 1.2 mm to 22.8 mm.
A further vibrotactile fMRI study was carried out involving patients with complex regional pain syndrome (CRPS). It has been suggested an altered central processing mechanism is involved in the disease, possibly due to cortical reorganisation in the sensory/motor cortices. The most efficient experimental protocols from the healthy subject studies were used to determine if these cortical differences were present in four patients. Data were acquired over two scanning sessions, approximately four months apart. The study revealed multiple SI foci and overlapping between the digits in both the healthy and CRPS hands, similar to those observed in the first studies. Larger SI activations were detected in one patient, smaller SI activations were detected in another patient and two patients demonstrated cluster sizes in the normal range. The cluster sizes and the changes in size between the two scans suggest a correlation with the amount of pain experienced by the patients.
A general lack of consistency in the results from all the studies may be attributed to the difficulty of reliably detecting SI activity at a field strength of 1.5 T.DAAR
The algebra of cell-zeta values
In this paper, we introduce cell-forms on , which are
top-dimensional differential forms diverging along the boundary of exactly one
cell (connected component) of the real moduli space
. We show that the cell-forms generate the
top-dimensional cohomology group of , so that there is a
natural duality between cells and cell-forms. In the heart of the paper, we
determine an explicit basis for the subspace of differential forms which
converge along a given cell . The elements of this basis are called
insertion forms, their integrals over are real numbers, called cell-zeta
values, which generate a -algebra called the cell-zeta algebra. By
a result of F. Brown, the cell-zeta algebra is equal to the algebra of
multizeta values. The cell-zeta values satisfy a family of simple quadratic
relations coming from the geometry of moduli spaces, which leads to a natural
definition of a formal version of the cell-zeta algebra, conjecturally
isomorphic to the formal multizeta algebra defined by the much-studied double
shuffle relations
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