Review of agricultural production systems in eastern Africa in relation to food and nutrition security and climate change

The goal of this paper is to provide a unified resource for Eritrea, Djibouti, Somaliland, Somalia, Ethiopia, Kenya, Uganda, Rwanda and Tanzania. For each country the review covers the topics of livestock production systems and agroecological zones, food and nutrition security, climate change, greenhouse gas (GHG) emissions and climate-smart agriculture (CSA) with a focus on the role of, or impact on, livestock systems. Each of these topics is broad and many excellent studies and reviews have been produced covering these topics either at the country level or for the entire East Africa region. It is the goal of this paper to provide an accessible introduction to these topics and to direct readers to the resources that exist for gathering detailed information on livestock production, food nutrition and security, climate change, GHG emissions and climate-smart livestock production in each country

The Genome and Methylome of a Subsocial Small Carpenter Bee, Ceratina calcarata

Understanding the evolution of animal societies, considered to be a major transition in evolution, is a key topic in evolutionary biology. Recently, new gateways for understanding social evolution have opened up due to advances in genomics, allowing for unprecedented opportunities in studying social behavior on a molecular level. In particular, highly eusocial insect species (caste-containing societies with nonreproductives that care for siblings) have taken center stage in studies of the molecular evolution of sociality. Despite advances in genomic studies of both solitary and eusocial insects, we still lack genomic resources for early insect societies. To study the genetic basis of social traits requires comparison of genomes from a diversity of organisms ranging from solitary to complex social forms. Here we present the genome of a subsocial bee, Ceratina calcarata. This study begins to address the types of genomic changes associated with the earliest origins of simple sociality using the small carpenter bee. Genes associated with lipid transport and DNA recombination have undergone positive selection in C. calcarata relative to other bee lineages. Furthermore, we provide the first methylome of a noneusocial bee. Ceratina calcarata contains the complete enzymatic toolkit for DNA methylation. As in the honey bee and many other holometabolous insects, DNA methylation is targeted to exons. The addition of this genome allows for new lines of research into the genetic and epigenetic precursors to complex social behaviors

Three venepuncture techniques in babies: a comparative study

Modifying hyodermic needles for blood sampling in babies is common. However, such techniques mean that medical devices are not always used as manufacturers intend and potential and actual risks associated with their use occur. A number of new devices have recently been designed to overcome safety issues. However, whether new devices are any more effective than existing modified methods is unknown. Through a randomoised controlled trial, this study attempted to compare the safety and efficacy of three blood sampling techniques in babies: (i) the 'broken' needle, (ii) the 'modified' buttrefly' and (iii) a new 'single winged' needle designed specifically for venepuncture in babies and young children. Eligibility criteria for inclusion to the study comprised: babies twelve months of age and under, weighing over 1500 grams, requiring at least three routine blood samples to monitor their condition, six hours apart. Informed, written parental consent was also required. The sample was drawn from a neonatal intensive care unit and achildren's unit in a large teaching hospital. Ethical approval for the study was gained form the local research ethics committee. Babies recruited into the study were randomised according to the order in which the three blood sampling techniques were used. Data were collected in terms of: (1) whether the blood sample had been obtained after one, two or more than two attempts; (2) whether there was clotting in the sample and (3) whether there was bruising and the extent of the bruising measured at the largest diamter of the bruise. Fourteen babies completed the study reulting in the trail being severely underpowered. Recruitment to the study was disappointing and was, in part, attributed to a number of adverse incidents that had occurred in clinical and research practices involving babies and children, that had gained much media attention, both before and during the study period

Simulation Evaluation of Controller-Managed Spacing Tools under Realistic Operational Conditions

Controller-Managed Spacing (CMS) tools have been developed to aid air traffic controllers in managing high volumes of arriving aircraft according to a schedule while enabling them to fly efficient descent profiles. The CMS tools are undergoing refinement in preparation for field demonstration as part of NASA's Air Traffic Management (ATM) Technology Demonstration-1 (ATD-1). System-level ATD-1 simulations have been conducted to quantify expected efficiency and capacity gains under realistic operational conditions. This paper presents simulation results with a focus on CMS-tool human factors. The results suggest experienced controllers new to the tools find them acceptable and can use them effectively in ATD-1 operations

Bifenthrin Baseline Susceptibility and Evaluation of Simulated Aerial Applications in \u3ci\u3eStriacosta albicosta\u3c/i\u3e (Lepidoptera: Noctuidae)

Striacosta albicosta (Smith) is a maize pest that has recently expanded its geographical range into the eastern United States and southeastern Canada. Aerial application of pyrethroids, such as bifenthrin, has been a major practice adopted to manage this pest. Reports of field failure of pyrethroids have increased since 2013. Striacosta albicosta populations were collected in 2016 and 2017 from maize fields in Nebraska, Kansas, and Canada and screened with bifenthrin active ingredient in larval contact dose-response bioassays. Resistance ratios estimated were generally low in 2016 (1.04- to 1.32-fold) with the highest LC50 in North Platte, NE (66.10 ng/cm2) and lowest in Scottsbluff, NE (50.10 ng/cm2). In 2017, O’Neill, NE showed the highest LC50 (100.66 ng/cm2) and Delhi, Canada exhibited the lowest (6.33 ng/cm2), resulting in a resistance ratio variation of 6.02- to 15.90-fold. Implications of bifenthrin resistance levels were further investigated by aerial application simulations. Experiments were conducted with a spray chamber where representative S. albicosta populations were exposed to labeled rates of a commercial bifenthrin formulation. Experiments resulted in 100% mortality for all populations, instars, insecticide rates, and carrier volumes, suggesting that levels of resistance estimated for bifenthrin active ingredient did not seem to impact the efficacy of the correspondent commercial product under controlled conditions. Results obtained from this research indicate that control failures reported in Nebraska could be associated with factors other than insecticide resistance, such as issues with the application technique, environmental conditions during and/or after application, or the insect’s natural behavior. Data generated will assist future S. albicosta resistance management programs

Development of the Multi Purpose Transportation System for the Space Launch System (SLS) Core Stage (CS) Flight Article

NASAs Multi Purpose Transportation System (MPTS) is designed to transport the Space Launch System vehicle segments by waterway and roadway. It is tasked with transporting the vehicle from where it is manufactured to its intermediate test location and final launch destination. Its design incorporates mechanisms that release degrees of freedom to prevent excessive loading during transit and ensure a successful delivery of the vehicle to its intended destination. In addition to the CS (Core Stage) flight article, the system will also move three structural test articles and a simulated CS Pathfinder (weight, center of gravity, outer mold line dimensions, and overall length) over road terrain on four NASA centers and on the Pegasus barge. The MPTS independently supports the article at both ends while communicating as a combined unit through automated monitoring of its released degree of freedom and corrective responses. This allows the system to constrain its payload in a statically determinate manner while traversing across highly variable terrain. Multi-body simulation of the transportation route is useful to predict free-body motion within the specified travel ranges. The MPTS has completed its design and analysis developmental cycles. This unpublished paper will describe the design challenges encountered in developing this system of large scale structure which incorporates complex mechanisms. The unique techniques and methodologies developed for analytical assessment of the hardware will be also be discussed. Key results from analytical evaluations as well as ongoing performance testing will be presented

Development of the Multi-Purpose Transportation System for the Space Launch System (SLS) Core Stage (CS) Flight Article

NASA's Multi-Purpose Transportation System (MPTS) is designed to transport the Space Launch System (SLS) vehicle segments by waterway and roadway. It is tasked with transporting the vehicle from where it is manufactured to its intermediate test location and final launch destination. Its design incorporates mechanisms that release degrees of freedom to prevent excessive loading during transit and ensure a successful delivery of the vehicle to its intended destination. In addition to the Core Stage (CS) flight article, the system will also move three Structural Test Articles (STAs), the Dynamic Demonstration Unit (DDU), and a simulated CS Pathfinder (weight, center of gravity, outer mold line dimensions, and overall length) over road terrain at four NASA centers and on the Pegasus barge. The MPTS independently supports the article at both ends while operating as a combined unit through automated monitoring of its released degree of freedom and corrective responses. This allows the system to constrain its payload in a statically determinate manner while traversing highly variable terrain. Multi-body simulation of the transportation route is useful to predict free-body motion within its range of mobility. The MPTS has completed its design and analysis developmental cycles. This paper describes the design challenges encountered in developing this system of large-scale structure, which incorporates complex mechanisms. The unique techniques and methodologies developed for analytical assessment of the hardware are also discussed

Differing Air Traffic Controller Responses to Similar Trajectory Prediction Errors: An Interrupted Time-Series Analysis of Controller Behavior

A Human-In-The-Loop simulation was conducted in January of 2013 in the Airspace Operations Laboratory at NASAs Ames Research Center. The simulation airspace included two en route sectors feeding the northwest corner of Atlantas Terminal Radar Approach Control. The focus of this paper is on how uncertainties in the studys trajectory predictions impacted the controllers ability to perform their duties. Of particular interest is how the controllers interacted with the delay information displayed in the meter list and data block while managing the arrival flows. Due to wind forecasts with 20-knot over-predictions and 20-knot under-predictions, delay value computations included errors of similar magnitude, albeit in opposite directions. However, when performing their duties in the presence of these errors, did the controllers issue clearances of similar magnitude, albeit in opposite directions

Moral panic and social theory: Beyond the heuristic

Copyright @ 2011 by International Sociological Association.Critcher has recently conceptualized moral panic as a heuristic device, or 'ideal type'. While he argues that one still has to look beyond the heuristic, despite a few exceptional studies there has been little utilization of recent developments in social theory in order to look 'beyond moral panic'. Explicating two current critical contributions - the first, drawing from the sociologies of governance and risk; the second, from the process/figurational sociology of Norbert Elias - this article highlights the necessity for the continuous theoretical development of the moral panic concept and illustrates how such development is essential to overcome some of the substantial problems with moral panic research: normativity, temporality and (un) intentionality

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex

The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein translocation are not well understood. The structure of the SecA–SecYEG complex revealed a 2-helix-finger (2HF) of SecA in an ideal position to contact the substrate protein and push it through the membrane. Surprisingly, immobilization of this finger at the edge of the protein channel had no effect on translocation, whereas its imposition inside the channel blocked transport. This analysis resolves the stoichiometry of the active complex, demonstrating that after the initiation process translocation requires only one copy each of SecA and SecYEG. The results also have important implications on the mechanism of energy transduction and the power stroke driving transport. Evidently, the 2HF is not a highly mobile transducing element of polypeptide translocation