A clinical study on Kalladaippu (Urolithiasis) with the evaluation of siddha drug Karpoora Silasathu Parpam

The clinical study on Kalladaippu was carried out in Post graduate department of Pothu Maruthuvam, Government Siddha Medical College, Aringar Anna Hospital, Chennai – 106 during the period of 2015-2017. A total of 40 patients were treated in the Outpatient department. The clinical and pathological assessment was carried out on the basis of Siddha and Modern aspects. All the patients were treated with Karpoora silasathu parpam with Ilaneer 130 mg b.d daily, after food for duration of 48days. males were mostly affected (57.5%). Most of the patients were in the age group between 31-40 years (52.5%). Most of the patients were from Neithal Thinai (82.5%). In this study, most of the cases (35%) were house wives. Most of the patients were affected in Muthuvenirkaalam (37.5%). In Vali, Abanan (100%), Viyanan (100%), Uthanan (30%), and Devadhathan (27.5%) was affected. In Azhal, Saathagam (100%), Ranjagam (22.5%) was affected. In Iyyam, Santhigam (30%) was affected. In Ezhu udal kattugal, Saaram (100%), Seneer (22.5%) and Enbu (30%) was affected. Regarding naadi, (60%) had Vatha Azhal was the most common naadi observed. The Toxicological studies of the trial medicine reveal no toxicity. The Pharmacological studies reveal that, the trial drug has Anti Urolithiatic activity. Bio- statistical analysis of the clinical trial reveals significant p value < 0.05 and ˂ 0.01 and concluded that the treatment is effective and significant. Regarding grading of the result, 17 cases (42.5%) shows good improvement, 19 cases (47.5%) shows moderate improvement, 4 cases (10%) shows poor improvement. CONCLUSION: Kalladaippu is a common disorder of pitha kutram. The dearranged pitham is settled down by the ingredients of trial medicine having astringent taste thereby the medicine acts as ethirurai maruthuvam to cure the disease. Most of the cases noted in muthuvenir kalam and elavenir kalam in my clinical trial. So, people should take all preventive measures during this period and take enough water. Toxicological study shows no acute and sub - acute toxicity. Pharmacological study reveals that the trial medicines possess Anti Urolithiatic activity. During clinical trial, no adverse reactions or complications were observed. The trial medicine Karpoora silasathu parpam showed good results with relieving symptoms in almost 90% patients. Once again Siddha medicine proves itself as a great boon to mankind

Multiphysics Analysis of a Magnetorheological Damper

&nbsp; &nbsp; &nbsp;A Magnetorheological damping has evolved as a potential tool in vibration control. The design of magnetorheological damping involves analysis of fluid flow principles and electromagnetic flux analysis. This research paper involves design and analysis of a magnetorheological damper employed for vibration control. The analysis is carried over by considering the domain as an axisymmetric model. The damping force of the damper depends upon the shear stress due to fluid viscosity and yield stress induced due to magnetic flux applied. The damping force generated by the damper is calculated

Luminescence Studies on Pr3+& Yb3+ Doped Cadmium Calcium Pyrophosphate Nanophosphors

The Cadmium Calcium Pyrophosphate doped with Pr3+ and Yb3+ was prepared by solution combustion synthesis. The luminescence studies and chromatic properties of the prepared sample were examined in the present study. The luminescence spectra of CdCaP: Pr3+ shows relevant peaks with emission at 599nm upon excitation of 445nm, whereas CdCaP: Yb3+ shows a peak at 536nm when excited with 254nm. The CIE 1931 chromaticity color coordinates for CdCaP: Pr3+ & CdCaP: Yb3+ were located in orange and greenish-yellow regions respectively. CCT and color purity values of the prepared samples were evaluated using McCam empirical formula and respective equation of color purity. Color Rendering Index (CRI) values of the prepared samples were calculated using the color calculator. © 2020 Author(s).Authors are thankful to UGC-DRS & DST-FIST, New Delhi for financial assistance to the department of physics, Acharya Nagarjuna University. One of the authors, Sk. Munimasthani expresses sincere thanks to UGC for providing financial support through MANF scheme (No. F1-17.1/2017-18/MANF-2017-18-AND-79002) to carry out the research work

Research Scenario of Bio Informatics in Big Data Approach

Big Data can unify all patient related data to get a 360-degree view of the patient to analyze and predict outcomes. This investigation examines the concepts and characteristics of Big Data, concepts about Translational Bio Informatics and some public available big data repositories and major issues of big data. This issue covers the area of medical and healthcare applications and its opportunities.

Luminescence studies on Pr3+&amp; Yb3+doped cadmium calcium pyrophosphate nanophosphors

The Cadmium Calcium Pyrophosphate doped with Pr3+ and Yb3+ was prepared by solution combustion synthesis. The luminescence studies and chromatic properties of the prepared sample were examined in the present study. The luminescence spectra of CdCaP: Pr3+ shows relevant peaks with emission at 599nm upon excitation of 445nm, whereas CdCaP: Yb3+ shows a peak at 536nm when excited with 254nm. The CIE 1931 chromaticity color coordinates for CdCaP: Pr3+ & CdCaP: Yb3+ were located in orange and greenish-yellow regions respectively. CCT and color purity values of the prepared samples were evaluated using McCam empirical formula and respective equation of color purity. Color Rendering Index (CRI) values of the prepared samples were calculated using the color calculator. © 2020 Author(s).Authors are thankful to UGC-DRS & DST-FIST, New Delhi for financial assistance to the department of physics, Acharya Nagarjuna University. One of the authors, Sk. Munimasthani expresses sincere thanks to UGC for providing financial support through MANF scheme (No. F1-17.1/2017-18/MANF-2017-18-AND-79002) to carry out the research work

Analytical Study of Base Isolation- A Review

Now a days the rate of happening of seismic events increasing and due to that so many structures got collapsed or damaged. In order to reduce the damage to structures during earthquakes, now a days the base isolation system is widely adopted and used over the world. This paper makes a wide review on the various base isolation techniques adopted and used. Different types of isolating bearings and materials used in it are reviewed. Here the review is done for the isolation system in normal R.C buildings (regular and irregular in plan) and also for bridges. The effect of base isolation system on some historic structures is also reviewed. The various advantages and disadvantages of different isolating bearings are reviewed. Here the effect of temperature on some isolating devices are also reviewed

Performance assessment on manufacturing of unfired bricks using industrial wastes

This paper presents eco-friendly unburnt bricks made up of fly ash, waste plastic powder, waste glass powder, lime, gypsum and crusher sand as alternatives to conventional burnt clay bricks for sustainable development. The research focuses on the maximum utilization of industrial waste in eco-friendly unburnt brick production. Materials are characterized according to their chemical and geotechnical properties. In this research, we use a milled waste glass powder of size less than 600μm and plastic powder obtained from plastic waste of size less than 600μm are added along with crushed sand, gypsum, lime and fly ash with various mix proportions concerning FaL-G mix concept. All the proportions were taken on a weight basis. Compressive strength, water absorption, and efflorescence are the key parameters chosen for comparing the innovative brick with conventional fly ash brick. There are five different mixes (Type A, B, C, D & E) are made in this research. The plastic and glass powders are replaced by crusher sand at the increased rate of 2% in every mix whereas 2%,4%,6%,8%, and 10%. It was found that the type B bricks have 17.63% strength was increased when compared to base mix. From the test results, type B bricks have enhanced mechanical performance when compared to all other mixes

Modelling of an Electromagnetic Space Propulsion System for Pulse Mode Operation

AbstractThe chemical rocket propulsion has limitations while applied to space application, with respect to specific impulse, delta-v, volume and stored energy, which can be overcome by electric propulsion system. Among various type of Electric propulsion system, the electromagnetic propulsion has added advantages for many space applications. In this paper an electromagnetic propulsion system is considered known as Magnetoplasmadynamic thrusters (MPD). The MPD thrust works based on principle of Lorentz force.The thruster is modeled based on Paschen's Law and snow plow model to operate it in pulsed mode to generate instantaneous peak thrust. This model includes the designing of high-current power supply, ignition circuit, and electrodes. Simulations have been performed by considering all the parameters involved in the model. The design parameters are analyzed for optimum value to get maximum thrust force