Development of data processing, interpretation and analysis system for the remote sensing of trace atmospheric gas species

The major emphasis is on the advancement of remote sensing technology. In particular, the gas filter correlation radiometer (GFCR) technique was applied to the measurement of trace gas species, such as carbon monoxide (CO), from airborne and Earth orbiting platforms. Through a series of low altitude aircraft flights, high altitude aircraft flights, and orbiting space platform flights, data were collected and analyzed, culminating in the first global map of carbon monoxide concentration in the middle troposphere and stratosphere. The four major areas of this remote sensing program, known as the Measurement of Air Pollution from Satellites (MAPS) experiment, are: (1) data acquisition, (2) data processing, analysis, and interpretation algorithms, (3) data display techniques, and (4) information processing

Investigation of reliability attributes and accelerated stress factors on terrestrial solar cells

Major effort during this reporting period was devoted to two tasks: improvement of the electrical measurement instrumentation through the design and construction of a microcomputer controlled short interval tester, and better understanding of second quadrant behavior by developing a mathematical model relating cell temperature to electrical characteristics. In addition, some preliminary work is reported on an investigation into color changes observed after stressing

Bond-disordered spin systems: Theory and application to doped high-Tc compounds

We examine the stability of magnetic order in a classical Heisenberg model with quenched random exchange couplings. This system represents the spin degrees of freedom in high-$T_\textrm{c}$ compounds with immobile dopants. Starting from a replica representation of the nonlinear $\sigma$-model, we perform a renormalization-group analysis. The importance of cumulants of the disorder distribution to arbitrarily high orders necessitates a functional renormalization scheme. From the renormalization flow equations we determine the magnetic correlation length numerically as a function of the impurity concentration and of temperature. From our analysis follows that two-dimensional layers can be magnetically ordered for arbitrarily strong but sufficiently diluted defects. We further consider the dimensional crossover in a stack of weakly coupled layers. The resulting phase diagram is compared with experimental data for La$_{2-x}$Sr$_x$CuO$_4$.Comment: 12 pages, 5 figure

Stable characteristic evolution of generic 3-dimensional single-black-hole spacetimes

We report new results which establish that the accurate 3-dimensional numerical simulation of generic single-black-hole spacetimes has been achieved by characteristic evolution with unlimited long term stability. Our results cover a selection of distorted, moving and spinning single black holes, with evolution times up to 60,000M.Comment: 4 pages, 3 figure

Gravitational wave extraction and outer boundary conditions by perturbative matching

We present a method for extracting gravitational radiation from a three-dimensional numerical relativity simulation and, using the extracted data, to provide outer boundary conditions. The method treats dynamical gravitational variables as nonspherical perturbations of Schwarzschild geometry. We discuss a code which implements this method and present results of tests which have been performed with a three dimensional numerical relativity code

Implementation Science Can Do Even More for Translational Ethics

In their paper “The ‘Ought-Is’ Problem,” Sisk and colleagues present a strong case for translating bioethics research and show how implementation science can help identify requirements and barriers for bioethics findings to be incorporated into practice (Sisk et al 2020). However, by showcasing only one type of implementation science framework, they leave out other potentially useful contributions implementation science can make to bioethics. In this commentary, we present three categories of implementation science frameworks: process models, frameworks for understanding implementation barriers and facilitators (discussed by Sisk and colleagues), and evaluative frameworks. We propose that process models and evaluative frameworks have much to contribute to translational bioethics because they give specific recommendations for how to design and evaluate implementation efforts

Boosted three-dimensional black-hole evolutions with singularity excision

Binary black hole interactions provide potentially the strongest source of gravitational radiation for detectors currently under development. We present some results from the Binary Black Hole Grand Challenge Alliance three- dimensional Cauchy evolution module. These constitute essential steps towards modeling such interactions and predicting gravitational radiation waveforms. We report on single black hole evolutions and the first successful demonstration of a black hole moving freely through a three-dimensional computational grid via a Cauchy evolution: a hole moving ~6M at 0.1c during a total evolution of duration ~60M

Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating

In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21. The core/shell structure was sprayed onto the surface of 316L stainless steel stents using a coaxial electrospray process with the aim of creating a coating that exhibited a differential release of the two drugs. The prepared stents displayed a uniform coating consisting of nano/micro particles. In vitro drug release experiments were performed, and we demonstrated that a biphasic mathematical model was capable of capturing the data, indicating that the release of the two drugs conformed to a diffusion-controlled release system. We demonstrated that our coating was capable of inhibiting the adhesion and activation of platelets, as well as the proliferation and migration of smooth muscle cells (SMCs), indicating its good biocompatibility and anti-proliferation qualities. In an in vivo porcine coronary artery model, the SZ-21/DTX drug-loaded hydrophobic core/hydrophilic shell particle coating stents were observed to promote re-endothelialization and inhibit neointimal hyperplasia. This core/shell particle-coated stent may serve as part of a new strategy for the differential release of different functional drugs to sequentially target thrombosis and in-stent restenosis during the vascular repair process and ensure rapid re-endothelialization in the field of cardiovascular disease