Random-field-induced disordering mechanism in a disordered ferromagnet: Between the Imry-Ma and the standard disordering mechanism

Random fields disorder Ising ferromagnets by aligning single spins in the direction of the random field in three space dimensions, or by flipping large ferromagnetic domains at dimensions two and below. While the former requires random fields of typical magnitude similar to the interaction strength, the latter Imry-Ma mechanism only requires infinitesimal random fields. Recently, it has been shown that for dilute anisotropic dipolar systems a third mechanism exists, where the ferromagnetic phase is disordered by finite-size glassy domains at a random field of finite magnitude that is considerably smaller than the typical interaction strength. Using large-scale Monte Carlo simulations and zero-temperature numerical approaches, we show that this mechanism applies to disordered ferromagnets with competing short-range ferromagnetic and antiferromagnetic interactions, suggesting its generality in ferromagnetic systems with competing interactions and an underlying spin-glass phase. A finite-size-scaling analysis of the magnetization distribution suggests that the transition might be first order.Comment: 12 pages, 7 figures, 4 table

Doubly perturbed S3S_3 neutrinos and the s13s_{13} mixing parameter

We further study a predictive model for the masses and mixing matrix of three Majorana neutrinos. At zeroth order the model yielded degenerate neutrinos and a generalized ``tribimaximal" mixing matrix. At first order the mass splitting was incorporated and the tribimaximal mixing matrix emerged with very small corrections but with a zero value for the parameter $s_{13}$. In the present paper a different, assumed weaker, perturbation is included which gives a non zero value for $s_{13}$ and further corrections to other quantities. These corrections are worked out and their consequences discussed under the simplifying assumption that the conventional CP violation phase vanishes. It is shown that the existing measurements of the parameter $s_{23}$ provide strong bounds on $s_{13}$ in this model.Comment: 8 page

Existence of a Thermodynamic Spin-Glass Phase in the Zero-Concentration Limit of Anisotropic Dipolar Systems

The nature of ordering in dilute dipolar interacting systems dates back to the work of Debye and is one of the most basic, oldest and as-of-yet unsettled problems in magnetism. While spin-glass order is readily observed in several RKKY-interacting systems, dipolar spin-glasses are subject of controversy and ongoing scrutiny, e.g., in ${{\rm LiHo_xY_{1-x}F_4}}$, a rare-earth randomly diluted uniaxial (Ising) dipolar system. In particular, it is unclear if the spin-glass phase in these paradigmatic materials persists in the limit of zero concentration or not. We study an effective model of ${{\rm LiHo_xY_{1-x}F_4}}$ using large-scale Monte Carlo simulations that combine parallel tempering with a special cluster algorithm tailored to overcome the numerical difficulties that occur at extreme dilutions. We find a paramagnetic to spin-glass phase transition for all Ho ion concentrations down to the smallest concentration numerically accessible of 0.1%, and including Ho ion concentrations which coincide with those studied experimentally up to 16.7%. Our results suggest that randomly-diluted dipolar Ising systems have a spin-glass phase in the limit of vanishing dipole concentration, with a critical temperature vanishing linearly with concentration, in agreement with mean field theory.Comment: 6 pages, 3 figures, 2 table

Novel disordering mechanism in ferromagnetic systems with competing interactions

Ferromagnetic Ising systems with competing interactions are considered in the presence of a random field. We find that in three space dimensions the ferromagnetic phase is disordered by a random field which is considerably smaller than the typical interaction strength between the spins. This is the result of a novel disordering mechanism triggered by an underlying spin-glass phase. Calculations for the specific case of the long-range dipolar LiHo_xY_{1-x}F_4 compound suggest that the above mechanism is responsible for the peculiar dependence of the critical temperature on the strength of the random field and the broadening of the susceptibility peaks as temperature is decreased, as found in recent experiments by Silevitch et al. [Nature (London) 448, 567 (2007)]. Our results thus emphasize the need to go beyond the standard Imry-Ma argument when studying general random-field systems.Comment: 4+2 pages, 3 figure

Double Threefold Degeneracies for Active and Sterile Neutrinos

We explore the possibility that the 3 active (doublet) neutrinos have nearly degenerate masses which are split only by the usual seesaw mechanism from 3 sterile (singlet) neutrinos in the presence of a softly broken $A_4$ symmetry. We take the unconventional view that the sterile neutrinos may be light, i.e. less than 1 keV, and discuss some very interesting and novel phenomenology, including a connection between the LSND neutrino data and solar neutrino oscillations.Comment: 8 pages, no figur

Role of Light Vector Mesons in the Heavy Particle Chiral Lagrangian

We give the general framework for adding "light" vector particles to the heavy hadron effective chiral Lagrangian. This has strong motivations both from the phenomenological and aesthetic standpoints. An application to the already observed D \rightarrow \overbar{K^*} weak transition amplitude is discussed.Comment: 19 pages, LaTeX documen

Magnetization of small lead particles

The magnetization of an ensemble of isolated lead grains of sizes ranging from below 6 nm to 1000 nm is measured. A sharp disappearance of Meissner effect with lowering of the grain size is observed for the smaller grains. This is a direct observation by magnetization measurement of the occurrence of a critical particle size for superconductivity, which is consistent with Anderson's criterion.Comment: 7 pages, 5 figures, Submitted to PR

Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout.

ObjectiveLesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI. The aim of the study was to investigate the long-term safety of LESU + XOI therapy.MethodsSafety data were pooled from three 12-month phase III (core) trials evaluating LESU 200 and 400 mg/day combined with an XOI (LESU200+XOI and LESU400+XOI), and two 12-month extension studies using descriptive statistics. To adjust for treatment duration, treatment-emergent adverse events (TEAEs) were expressed as exposure-adjusted incidence rates (patients with events per 100 person-years).ResultsIn the core studies, exposure-adjusted incidence rates for total and total renal-related TEAEs were comparable for XOI alone and LESU200+XOI but higher with LESU400+XOI. Exposure-adjusted incidence rates for serum creatinine (sCr) elevations ⩾1.5×baseline were 2.9, 7.3 and 18.7, respectively. Resolution (sCr ⩽1.2×baseline) occurred in 75-90% of all events, with 66-75% occurring without any study medication interruption. Major adverse cardiovascular events were 3, 4 and 9 with XOI, LESU200+XOI and LESU400+XOI, respectively. Longer exposure in core+extension studies did not increase rates for any safety signals.ConclusionAt the approved dose of 200 mg once-daily combined with an XOI, LESU did not increase renal, cardiovascular or other adverse events compared with XOI alone, except for sCr elevations. With extended exposure in the core+extension studies, the safety profile was consistent with that observed in the core studies, and no new safety concerns were identified

Effects of Symmetry Breaking on the Strong and Electroweak Interactions of the Vector Nonet

Starting from a chiral invariant and quark line rule conserving Lagrangian of pseudoscalar and vector nonets we introduce first and second order symmetry breaking as well as quark line rule violating terms and fit the parameters, at tree level, to many strong and electroweak processes. A number of predictions are made. The electroweak interactions are included in a manifestly gauge invariant manner. The resulting symmetry breaking pattern is discussed in detail. Specifically, for the ``strong'' interactions, we study all the vector meson masses and V -> \phi \phi decays, including isotopic spin violations. In the electroweak sector we study the { rho^0 , omega , phi } -> e^+e^- decays, { pi^+ , K^+ , K^0 } ``charge radii'', K_{l3} ``slope factor'' and the overall e^+e^- -> pi^+ pi^- process. It is hoped that the resulting model may be useful as a reasonable description of low energy physics in the range up to about 1 GeV.Comment: 43 pages (LaTeX), 5 PostScript figures are included as uuencoded-compressed-tar file at the en