Update on the use of alitretinoin in treating chronic hand eczema

Chronic hand eczema is a debilitating dermatological condition with significant economic, social, and functional impacts. To date, conventional treatments such as topical corticosteroids, phototherapy, and systemic immunosuppressants have yielded disappointing results, owing to either a lack of efficacy or significant adverse events. Oral alitretinoin (9-cis-retinoic acid) is a unique panagonist retinoid with immunomodulatory and anti-inflammatory activity that has emerged as a novel treatment for chronic hand eczema. Several large-scale clinical studies have demonstrated oral alitretinoin’s high efficacy rate of 28% to 89%, its safe tolerability profile, and its positive impact on quality of life, validating it as a therapeutic option for patients with severe chronic hand eczema refractory to standard treatment

An Investigation of the Backgrounds of Health Sciences Librarians

The purpose of this study was to investigate the educational and professional backgrounds of health sciences librarians currently working in the U.S. and Canada. A survey consisting of 15 questions was created using the software program Qualtrics. 389 total surveys were received. Respondents reported having a wide variety of educational and professional backgrounds. Only about 22% of respondents reported having health sciences work experience prior to entering the field. Recruitment into the field of health sciences librarianship should take a broad approach, and professional development efforts should appeal to a wide array of experience levels

The Trials & Tribulations of incorporating 3D Printing into the Health Science Curriculum

In May 2015, our library was granted an NNLM MAR Medical Library Project Award to purchase a 3D printer and incorporate its’ use into the health science curriculum. No one on our staff had any prior experience with 3D printing. What we did have was an interest in offering new and innovative library services. We also wanted to promote the library as a partner in introducing new technologies to our students. Therefore, we forged ahead and learned all we could very quickly in order to get the program up and running. During brainstorming sessions with our Occupational and Physical Therapy departments, it was agreed that a valuable experience for our students would be for them to design and print a custom assistive device for a patient. Our plan was for the Librarians, OT & PT faculty and IT staff to attend a 2-day training in 3D printing and design. Then the Librarians and faculty would train the students in two different graduate courses to design and print a custom assistive device. The IT staff would help with the installation and maintenance of the printer. The 3D printer would be housed in the library where all the involved parties could have access to it for the greatest number of hours and the printing would be supervised by library staff. What we didn’t foresee was that a 2-day training was not enough to learn the design skills needed to create the assistive devices. We felt we had learned what we needed to get started running the printer, but designing objects to print was a more technical process that required skills and expertise beyond our introductory knowledge. The design software was completely foreign from any other types of software the Librarians and faculty had experience with and we were intimidated and overwhelmed by the end of the 2nd day. In addition, no one realized the noise that a 3D printer makes and how that would affect students studying in the library. Others might have given up at this point, but we wanted to complete the project somehow. With a little luck, a little serendipity, and a lot of determination, we found a solution. But it didn’t solve all the problems and our solution created new problems. We kept working through them and have found the experience to be worthwhile and valuable for everyone involved. In this presentation we would like to share how we managed the unexpected problems and also share our successes and continuing challenges. The key takeaways will be tools for evaluating 3D printers, training or finding partnerships for file creation, and effectively situating a 3D printer within the physical space of the library

A Reconsideration of library treatment of ethically questionable medical texts: The case of the Pernkopf Atlas of Anatomy

The Pernkopf Atlas of Anatomy consists of anatomical drawings created by Austrian physician Eduard Pernkopf, an active member of the Nazi Party during World War II. While the book was known for its highly detailed anatomical drawings, in the 1990s it was determined that Holocaust victims were likely used as subjects for the drawings. Using a survey, the authors aimed to gather information about the presence of this monograph in academic libraries today to provide best practice recommendations for academic libraries in their approach to ethically questionable materials

Der Tatbegriff des § 24 StGB

Ein Straftatversuch verläuft oft anders, als der Täter ihn sich bei Beginn vorstellte. Ob trotz solcher Änderungen das dem Täter mögliche Weiterhandeln noch Fortsetzung des begonnenen Versuchs wäre, hängt von der Auslegung des Tatbegriffs ab, davon also, ob das Ausgeführte mit dem Möglichen zu einer „Tat“ i.S.d. § 24 StGB verschmelzen würde. Rechtsprechung und Teile der Literatur haben diese Fragestellung aus dem Blick verloren und lösen problematische Fälle über die Anwendung gesetzesfremder Begriffe und ungeschriebener Rechtsfiguren. Die methodische Überzeugung des Autors ist es, dass dieser Weg in die Irre führt. Er stellt daher früh die Weiche, allein das Gesetz entscheidend sein zu lassen. Seine Ergebnisse gewinnt er aus einer methodengerechten Auslegung des § 24 StGB

Cervical Intramedullary Epidermoid Cyst with Liquid Contents

Intramedullary spinal epidermoid cysts are benign ectopic embryological growths with reported incidence of less than 1% of intramedullary tumors. In this case we report an unusual cervical intramedullary epidermid with liquid contents. A 40-year-old patient presented with progressive weakness of all four limbs of four months duration, bowel and bladder disturbances of two days duration, pain and paresthesias in all four limbs. Magnetic resonance imaging (MRI) revealed a well defined intramedullary lesion extending from C2-C3 level with widening of the cord. The lesion was hypointense on T1W images, hyperintense on T2W and fluid attenuation and inversion recovery images with thin rim of enhancement after contrast administration. Histopathological examination of the excised specimen revealed epidermal lining and keratinous material features of an epidermoid cyst. As in present case, rarely epidermoid cyst can have clear contents, and an MRI finding can closely mimic the features of arachnoid cyst, findings not classical and is different than described in literature