1,190 research outputs found
Naturgeschichte der in der Schweiz einheimischen Säugethiere: ein Handbuch für Kenner und Liebhaber
Damping of spin waves and singularity of the longitudinal modes in the dipolar critical regime of the Heisenberg-ferromagnet EuS
By inelastic scattering of polarized neutrons near the (200)-Bragg
reflection, the susceptibilities and linewidths of the spin waves and the
longitudinal spin fluctuations were determined separately. By aligning the
momentum transfers q perpendicular to both \delta S_sw and the spontaneous
magnetization M_s, we explored the statics and dynamics of these modes with
transverse polarizations with respect to q. In the dipolar critical regime,
where the inverse correlation length kappa_z(T) and q are smaller than the
dipolar wavenumber q_d, we observe:(i) the static susceptibility of \delta
S_sw^T(q) displays the Goldstone divergence while for \delta S_z^T(q) the
Ornstein-Zernicke shape fits the data with a possible indication of a
thermal(mass-)renormalization at the smallest q-values, i.e. we find
indications for the predicted 1/q divergence of the longitudinal
susceptibility; (ii) the spin wave dispersion as predicted by the
Holstein-Primakoff theory revealing q_d=0.23(1)\AA^{-1}in good agreement with
previous work in the paramagnetic and ferromagnetic regime of EuS; (iii) within
experimental error, the (Lorentzian) linewidths of both modes turn out to be
identical with respect to the q^2-variation, the temperature independence and
the absolute magnitude. Due to the linear dispersion of the spin waves they
remain underdamped for q<q_d. These central results differ significantly from
the well known exchange dominated critical dynamics, but are quantitatively
explained in terms of dynamical scaling and existing data for T>=T_C. The
available mode-mode coupling theory, which takes the dipolar interactions fully
into account, describes the gross features of the linewidths but not all
details of the T- and q-dependencies. PACS: 68.35.Rh, 75.40.GbComment: 10 pages, 7 figure
Critical Dynamics of Magnets
We review our current understanding of the critical dynamics of magnets above
and below the transition temperature with focus on the effects due to the
dipole--dipole interaction present in all real magnets. Significant progress in
our understanding of real ferromagnets in the vicinity of the critical point
has been made in the last decade through improved experimental techniques and
theoretical advances in taking into account realistic spin-spin interactions.
We start our review with a discussion of the theoretical results for the
critical dynamics based on recent renormalization group, mode coupling and spin
wave theories. A detailed comparison is made of the theory with experimental
results obtained by different measuring techniques, such as neutron scattering,
hyperfine interaction, muon--spin--resonance, electron--spin--resonance, and
magnetic relaxation, in various materials. Furthermore we discuss the effects
of dipolar interaction on the critical dynamics of three--dimensional isotropic
antiferromagnets and uniaxial ferromagnets. Special attention is also paid to a
discussion of the consequences of dipolar anisotropies on the existence of
magnetic order and the spin--wave spectrum in two--dimensional ferromagnets and
antiferromagnets. We close our review with a formulation of critical dynamics
in terms of nonlinear Langevin equations.Comment: Review article (154 pages, figures included
Lower cortical thickness and increased brain aging in adults with cocaine use disorder
Background: Cocaine use disorder (CUD) is a global health issue with severe behavioral and cognitive sequelae. While previous evidence suggests a variety of structural and age-related brain changes in CUD, the impact on both, cortical thickness and brain age measures remains unclear. Methods: Derived from a publicly available data set (SUDMEX_CONN), 74 CUD patients and 62 matched healthy controls underwent brain MRI and behavioral-clinical assessment. We determined cortical thickness by surface-based morphometry using CAT12 and Brain Age Gap Estimate (BrainAGE) via relevance vector regression. Associations between structural brain changes and behavioral-clinical variables of patients with CUD were investigated by correlation analyses. Results: We found significantly lower cortical thickness in bilateral prefrontal cortices, posterior cingulate cortices, and the temporoparietal junction and significantly increased BrainAGE in patients with CUD [mean (SD) = 1.97 (±3.53)] compared to healthy controls ( p < 0.001, Cohen’s d = 0.58). Increased BrainAGE was associated with longer cocaine abuse duration. Conclusion: Results demonstrate structural brain abnormalities in CUD, particularly lower cortical thickness in association cortices and dose-dependent, increased brain age
A Computed Tomography Vertebral Segmentation Dataset with Anatomical Variations and Multi-Vendor Scanner Data
With the advent of deep learning algorithms, fully automated radiological
image analysis is within reach. In spine imaging, several atlas- and
shape-based as well as deep learning segmentation algorithms have been
proposed, allowing for subsequent automated analysis of morphology and
pathology. The first Large Scale Vertebrae Segmentation Challenge (VerSe 2019)
showed that these perform well on normal anatomy, but fail in variants not
frequently present in the training dataset. Building on that experience, we
report on the largely increased VerSe 2020 dataset and results from the second
iteration of the VerSe challenge (MICCAI 2020, Lima, Peru). VerSe 2020
comprises annotated spine computed tomography (CT) images from 300 subjects
with 4142 fully visualized and annotated vertebrae, collected across multiple
centres from four different scanner manufacturers, enriched with cases that
exhibit anatomical variants such as enumeration abnormalities (n=77) and
transitional vertebrae (n=161). Metadata includes vertebral labelling
information, voxel-level segmentation masks obtained with a human-machine
hybrid algorithm and anatomical ratings, to enable the development and
benchmarking of robust and accurate segmentation algorithms.Comment: 18 pages, 2 figures, 2 tables; Hans Liebl, David Schinz equally
contributed to this manuscrip
Claustrum volumes are lower in schizophrenia and mediate patients' attentional deficits
BACKGROUND: While the last decade of extensive research revealed the prominent role of the claustrum for mammalian forebrain organization, i.e., widely distributed claustral-cortical circuits coordinate basic cognitive functions such as attention, it is poorly understood whether the claustrum is relevant for schizophrenia and related cognitive symptoms. We hypothesized firstly, that claustrum volumes are lower in schizophrenia and secondarily, that potentially lower volumes mediate patients' attention deficits.METHODS: Based on T1-weighted MRI, advanced automated claustrum segmentation, and attention symbol coding task (SCT) in 90 patients with schizophrenia and 96 healthy controls from two independent sites, the COBRE open-source database and MUNICH dataset, we compared total-intracranial-volume-normalized claustrum volumes and SCT scores across groups via ANCOVA and related variables via correlation and mediation analysis.RESULTS: Patients had lower claustrum volumes of about 13 % (p<0.001, Hedges g=0.63), which not only correlated with (r=0.24, p=0.014) but also mediated lower SCT scores (indirect effect ab = -1.30 ± 0.69; CI [-3.73; -1.04]). Results were not confounded by age, sex, global and claustrum-adjacent gray matter changes, scanner site, smoking, and medication.CONCLUSIONS: Results demonstrate lower claustrum volumes that mediate patients' attention deficits in schizophrenia. Data indicate the claustrum as being relevant for schizophrenia pathophysiology and cognitive functioning.</p
Differentiation of benign and malignant vertebral fractures using a convolutional neural network to extract CT-based texture features.
PURPOSE
To assess the diagnostic performance of three-dimensional (3D) CT-based texture features (TFs) using a convolutional neural network (CNN)-based framework to differentiate benign (osteoporotic) and malignant vertebral fractures (VFs).
METHODS
A total of 409 patients who underwent routine thoracolumbar spine CT at two institutions were included. VFs were categorized as benign or malignant using either biopsy or imaging follow-up of at least three months as standard of reference. Automated detection, labelling, and segmentation of the vertebrae were performed using a CNN-based framework ( https://anduin.bonescreen.de ). Eight TFs were extracted: Varianceglobal, Skewnessglobal, energy, entropy, short-run emphasis (SRE), long-run emphasis (LRE), run-length non-uniformity (RLN), and run percentage (RP). Multivariate regression models adjusted for age and sex were used to compare TFs between benign and malignant VFs.
RESULTS
Skewnessglobal showed a significant difference between the two groups when analyzing fractured vertebrae from T1 to L6 (benign fracture group: 0.70 [0.64-0.76]; malignant fracture group: 0.59 [0.56-0.63]; and p = 0.017), suggesting a higher skewness in benign VFs compared to malignant VFs.
CONCLUSION
Three-dimensional CT-based global TF skewness assessed using a CNN-based framework showed significant difference between benign and malignant thoracolumbar VFs and may therefore contribute to the clinical diagnostic work-up of patients with VFs
Differentiation of benign and malignant vertebral fractures using a convolutional neural network to extract CT-based texture features
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