THE COMPOSITION OF THE POOR IN THB REPUBLIC OF IRELAND: A SURVEY OF PREVIOUS RESEARCH. ESRI Working Paper No. 5, February 1988

This paper surveys the available research on the nature of poverty in Ireland. It focuses mainly on the composition of the poor. The paper summarises for the reader the results of the available research on the characteristics of the groups and categories of people most in need. It illustrates some of the conceptual and methodological problems in the measurement of poverty while making the reader aware of some of approaches used in Ireland to tackle these problems

University of Dayton\u27s Fitz Center: Leadership in Building Community

The University of Dayton\u27s Raymond L. Fitz, S. M., Center for Leadership in Community has a long history that is emblematic of its mission to "initiate and sustain partnerships with urban neighborhoods and larger communities by working at comprehensive community building and providing a context for connected learning and scholarship" (Raymond L. Fitz, S. M., Center for Leadership in Community 2005 ). As the centralized unit for the University of Dayton\u27s civic engagement efforts, the Fitz Center demonstrates the necessary and sufficient qualities that has made it an exemplary model of Campus Compact\u27s Mechanism and Resources indicators at a comprehensive, urban university

Optimasi Metode Cryotherapy Untuk Mengeliminasi Virus Pada Tunas Kentang in Vitro

Penggunaan benih kentang generasi awal dan bebas virus merupakan kunci keberhasilan produksi kentang berkualitas. Cryotherapy (perendaman dalam nitrogen cair) merupakan teknik terbaru untuk mengeliminasi virus pada benih kentang. Salah satu kendala dalam penerapan teknologi cryotherapy ialah tingkat daya hidup eksplan yang masih rendah. Penelitian ini bertujuan untuk mengetahui efektifitas teknik enkapsulasi-dehidrasi untuk mendapatkan tunas yang sehat setelah perendaman dalam nitrogen cair. Ujung tunas in vitro ukuran 2–3 mm dari empat genotipe kentang di prakultur selama 3 hari secara bertahap pada media MS dengan penambahan gula 0,25 M, 0,5 M, dan 0, 75 M. Kemudian tunas dienkapsulasi, didehidrasi selama 5 jam, lalu direndam dalam nitrogen cair selama 60 menit lalu dihangatkan kembali dalam waterbath selama 3 menit. Tunas dalam kapsul kemudian dikulturkan pada media MS +30 g/l sukrosa + 8 g/l agar + 0,4 mg/l BAP + 1 mg/l GA3 untuk pemulihan, lalu dipelihara di ruang kultur dengan suhu 24oC. Daya hidup ujung tunas diamati pada minggu ke-8 dengan menggunakan kriteria skoring sebagai berikut: (1) pemutihan jaringan dan tidak ada respons pertumbuhan, (2) kalus mencokelat, (3) kalus hijau, (4) tumbuh tunas, dan (5) planlet sehat. Hasil penelitian menunjukkan daya hidup ujung tunas bervariasi antargenotipe. Skor daya hidup berkisar 1–2 (frekuensi 2–10) pada perlakuan nitrogen cair, yang menunjukkan tidak ada respons pertumbuhan tunas, beberapa memperlihatkan pertumbuhan kalus. Tunas pada perlakuan kontrol (tanpa perendaman dalam nitrogen cair) menunjukkan skor daya hidup 5 (frekuensi 1–7), di mana ujung tunas mampu beregenerasi menjadi planlet

Community Partner Indicators of Engagement: An Action Research Study on Campus-Community Partnership

The central purpose of this research study was to develop common indicators of engagement for civic initiatives between institutions of higher education and their community organization partners. The unique aspect of this study was that the indicators were generated by the community organizations participating as stakeholders in campus-community partnerships. Using an action research methodology that involved eleven community organization participants from the health and wellness sector, the study advocated for research that provided a deeper understanding of the perspectives of community organizations. Findings suggested that significant divides existed in core civic areas dealing with service-learning, relevance of academic research, and equitable treatment of community partners. The study produced a formal set of community partner indicators of engagement that were developed by the participants in the study and disseminated to higher education leaders. The indicators illustrated the expectations of community partners that engaged in civic partnerships with higher education. Additionally, the study provided an analysis of the literature on civic engagement, identifying a lack of empirical research concerned with the perspectives of community organization partners. The electronic version of the dissertation is accessible at the OhioLINK ETD center http://www.ohiolink.edu/etd/

Higher Education Exchange: 2008

This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share.The Higher Education Exchange is founded on a thought articulated by Thomas Jefferson in 1820: "I know no safe depository of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."In the tradition of Jefferson, the Higher Education Exchange agrees that a central goal of higher education is to help make democracy possible by preparing citizens for public life. The Higher Education Exchange is part of a movement to strengthen higher education's democratic mission and foster a more democratic culture throughout American society.Working in this tradition, the Higher Education Exchange publishes interviews, case studies, analyses, news, and ideas about efforts within higher education to develop more democratic societies

Justifications for K-12 education standards, goals, and curriculum

In the contemporary U.S., the state, through the Legislative Assembly, the State Board of Education, and the Department of Education, sets policies for K-12 education. These include goals and standards that affect the kinds of influences local officials, parents, and students can have on various education programs, required and elective coursework, graduation requirements, and curriculum content. The state ought to be able to justify their education policies to citizens. I argue here for a pragmatist informed "minimalist approach" to justifying education policies. This approach has state officials (and subsequently local officials) use local, situated reasons for justifying their education standards, goals, and curriculum. I argue that if state officials utilize a minimalist approach to justify education policies, it will be easier for citizens to contest (or support) the state's policies because the language employed will better represent citizen's local, situated common experiences, and be contestable on those grounds. One consequence of this minimalist approach is that state officials could exclude justifications that are made by appealing to isolated, abstract conceptions. Isolated, abstract conceptions are, as pragmatists such as Rorty have argued, transcendental in nature and doomed to failure; fortunately, as the pragmatist defense of a minimalist approach shows, they are also unnecessary. Some implications of adopting a pragmatist-informed approach is that the state should give up terms and phrases that attempt to (i) construct a unifying theory for justification or for truth; (ii) construct and somehow universally justify a single best particular method for interpreting texts and analyzing scientific processes; and/or (iii) construct comprehensive and complete standards. Rather, state officials ought to identify local, situated reasons for particular policies. From these local appeals, state officials could construct a minimal set of education policies that leave room for local officials and teachers to have particular freedoms in constructing programs, projects, and curricula. I approach this argument through a critique of select education policies in Oregon, Texas, Arizona, and Tennessee. I argue that these policies, like many education policies and standards, lack adequate justifications. Those justifications that are provided are too vague and susceptible to interpretations that are not relevant to the particular purposes of the policies. For instance, certain policies have illegitimately led to the denial of funding for "Ethnic Studies" programs in Arizona, or allowed for irrelevant teacher and student criticisms of theories within the sciences to be explored and entertained as legitimate in Tennessee classrooms. My recommendations, if followed, would give state officials grounds for excluding the concerns of citizens that are not relevant to particular policies and provide a legitimate, justifiable basis for constructing state education policies

Metformin Uptake and Translocation in Chickpeas: Determination Using Liquid Chromatography−Mass Spectrometry

Multiple chronic conditions (MCCs) such as diabetes, hypertension, heart disease, arthritis, asthma, and common respiratory problems are prevalent in over one-fourth of Americans, and separate drugs are prescribed to manage each of the diseases. The nutritive crop seeds loaded with multiple drugs could be a cheap and sustainable alternative to drugs produced by pharmaceutical companies. Our long-term goal is to produce chickpea seeds containing comparable dosages of multiple drugs regularly prescribed for managing MCC. In this work, we conducted experiments to understand the uptake and translocation of metformin into the tissues of chickpea to demonstrate the applicability of LC–HR-ToF-MS in determining metformin concentration, and to investigate responses of increased dosage of metformin and it’s accumulation into the chickpea seed. We treated the chickpea plants with 100 and 500 mg/L metformin chloride and analyzed its concentration in the leaf, stem, and seeds. We observed that metformin was successfully uptaken by chickpeas plant and translocated to stem, leaf, and seeds in both treatments. We also observed that the metformin concentration is responsive and as high as 349 times increase in seed when the dosage was increased from 100 to 500 mg/L

A conceptual framework for negotiating public involvement in municipal waste management decision-making in the UK

The technical expertise that politicians relied on in the past to produce cost-effective and environmentally sound solutions no longer provides sufficient justification to approve waste facilities. Local authorities need to find more effective ways to involve stakeholders and communities in decision-making since public acceptance of municipal waste facilities is integral to delivering effective waste strategies. This paper presents findings from a research project that explored attitudes towards greater levels of public involvement in UK waste management decision-making. The study addressed questions of perception, interests, the decision context, the means of engagement and the necessary resources and capacity for adopting a participatory decision process. Adopting a mixed methods approach, the research produced an empirical framework for negotiating the mode and level of public involvement in waste management decision-making. The framework captures and builds on theories of public involvement and the experiences of practitioners, and offers guidance for integrating analysis and deliberation with public groups in different waste management decision contexts. Principles in the framework operate on the premise that the decision about ‘more’ and ‘better’ forms of public involvement can be negotiated, based on the nature of the waste problem and wider social context of decision-making. The collection of opinions from the wide range of stakeholders involved in the study has produced new insights for the design of public engagement processes that are context-dependent and ‘fit-for-purpose’; these suggest a need for greater inclusivity in the case of contentious technologies and high levels of uncertainty regarding decision outcomes

Testing gravitational-wave searches with numerical relativity waveforms: Results from the first Numerical INJection Analysis (NINJA) project

The Numerical INJection Analysis (NINJA) project is a collaborative effort between members of the numerical relativity and gravitational-wave data analysis communities. The purpose of NINJA is to study the sensitivity of existing gravitational-wave search algorithms using numerically generated waveforms and to foster closer collaboration between the numerical relativity and data analysis communities. We describe the results of the first NINJA analysis which focused on gravitational waveforms from binary black hole coalescence. Ten numerical relativity groups contributed numerical data which were used to generate a set of gravitational-wave signals. These signals were injected into a simulated data set, designed to mimic the response of the Initial LIGO and Virgo gravitational-wave detectors. Nine groups analysed this data using search and parameter-estimation pipelines. Matched filter algorithms, un-modelled-burst searches and Bayesian parameter-estimation and model-selection algorithms were applied to the data. We report the efficiency of these search methods in detecting the numerical waveforms and measuring their parameters. We describe preliminary comparisons between the different search methods and suggest improvements for future NINJA analyses.Comment: 56 pages, 25 figures; various clarifications; accepted to CQ

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency

The barrier to HIV cure is the HIV reservoir, which is composed of latently infected CD4+ T cells and myeloid cells that carry stably integrated and replication-competent provirus. The gastrointestinal tract (GIT) contains a substantial part of the HIV reservoir and its immunophysiology could be especially conducive for HIV persistence and reactivation. However, the exact cellular microenvironment and molecular mechanisms that govern the renewal of provirus-harboring cells and proviral reactivation in the GIT remain unclear. In this review, we outline the evidence supporting an overarching hypothesis that interferon activity driven by specialized enterocytes creates a microenvironment that fosters proliferation of latently infected CD4+ T cells and sporadic HIV reactivation from these cells. First, we describe unique immunologic features of the gastrointestinal associated lymphoid tissue (GALT), specifically highlighting IFN activity in specialized enterocytes and potential interactions between these cells and neighboring HIV susceptible cells. Then, we will describe dysregulation of IFN signaling in HIV infection and how IFN dysregulation in the GALT may contribute to the persistence and reactivation of the latent HIV reservoir. Finally, we will speculate on the clinical implications of this hypothesis for HIV cure strategies and outline the next steps