407 research outputs found
The effects of tactile/kinesthetic instructional strategies in the biology classroom
The purpose of this study was to determine whether the addition of tactile/kinesthetic instruction to the biology classroom could significantly increase learning. Various kinds of tactile/kinesthetic lessons were taught to three experimental groups who also received visual and auditory instruction. These tactile/kinesthetic lessons included task cards, task puzzles, manipulatives, total body movement, and large floor games. The control group only received visual and auditory instruction. The subjects were 84 College Biology students from Buena Regional High School, a school in rural South Jersey. The classes varied in gender and race. The same instructor taught all classes and the length of the study was six weeks. The content area used in this study was cellular reproduction. Tests and quizzes were used to measure the learning. Analysis of a pre study chapter test was performed using the t test. No significant differences were found at the 95% level for all class pairings. The t test was also performed on four quizzes and two tests taken during and immediately after the study. This statistical test was performed on all possible class pairings also. Only differences at the 95% level were considered. No differences were found between any of the class pairings. It was concluded that the addition of tactile/kinesthetic instruction to the biology classroom does not increase learning
Use of Another\u27s Trademark in a Web Page Meta Tag: Why Liability Should Not Ensue Under the Lanham Act for Trademark Infringement
This Comment argues that liability for trademark infringement should not ensue under the Lanham Act when an unauthorized user incorporates a senior holder\u27s registered trademark in a web page meta tag.4 Part I discusses the Lanham Act and the various elements that must be satisfied in order to prevail on a cause of action for trademark infringement. Part II provides a background of the Internet and World Wide Web. Part III discusses how a typical cause of action for trademark infringement in this situation may arise. Part IV analyzes the issue and demonstrates why liability should not ensue. In short, the argument takes the position that an action for trademark infringement stemming from the unauthorized use of another\u27s trademark in a meta tag cannot be sustained
How Childhood Maltreatment Shapes Brain Regions: Considerations for Speech-Language Pathology
Childhood maltreatment is a pervasive issue that affects millions of children worldwide, leading to alterations in key structures such as the limbic system, basal ganglia, corpus callosum, visual cortex, and language areas. These changes result in significant cognitive, emotional, and neurological consequences, such as learning deficits, emotional regulation issues, memory problems, reduced vocabulary size, speech errors, etc. This thesis explores the neurological effects of childhood maltreatment and their implications for speech-language pathology, highlighting how maltreatment-induced brain changes affect areas within the scope of speech-language pathology, such as social communication, language development, and behavior management. These results underscore the importance of adopting trauma-informed care practices. Understanding these connections and implementing trauma-informed care is crucial for developing effective strategies to support maltreated children, ultimately improving their outcomes and quality of life
8-Year-Old Child with Cerebral Palsy Treated with Pelvic Osteotomies Using 3.5 mm Blade Plate Having Subsequent Bilateral Implant Aseptic Loosening: A Case Report
Background: Cerebral palsy (CP) is a central problem of the brain due to neurological insult that affects muscle posture, tone, and movement, resulting in poor motor control and dysfunctional muscle balance affecting hip joints in the growing child. Surgical treatment of hip and, if present, acetabular dysplasia addresses the femoral neck-shaft angle, appropriate muscle lengthening, and deficiency of acetabular coverage, as necessary. The surgeons perform proximal femoral osteotomies (PFOs) mostly with fixed angled blade plates (ABP) with proven success. The technique using an ABP is common and requires detailed attention to perform and to teach.
The case: In this case, an eight-year-old ambulatory patient with CP underwent bilateral proximal varus femoral derotational and pelvic osteotomies for the neuromuscular hip condition with a 3.5 mm Locking Cannulated Blade System (OP-LCP) by OrthoPediatrics Corp instead of the use of the conventional 4.5 mm ABP procedure, resulting in aseptic loosening.
Conclusion: Due to the child’s underdeveloped posture, the surgeon utilized the 3.5 mm instrumentation for a child-size implant, which worked sufficiently for the surgery but may not have loosened if a similar child-size blade plate system of 4.5 mm screws was implanted. While the ABP and OP-LCP systems are effective and safe for internal corrections of PFOs, the OP-LCP system may aid the residents in learning the procedure with higher confidence, fewer technical inaccuracies, and refined outcomes. Both systems are safer and viable for the treatment of neuromuscular hip conditions
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A Student-Designed Potentiometric Titration: Quantitative Determination of Iron(II) by Caro's Acid Titration
Article on a student-designed potentiometric titration and a quantitative determination of iron(II) by Caro's acid titration
Attitudes toward Methadone among Out-of-Treatment Minority Injection Drug Users: Implications for Health Disparities
Injection drug use (IDU) continues to be a significant public health issue in the U.S. and internationally, and there is evidence to suggest that the burden of injection drug use and associated morbidity and mortality falls disproportionately on minority communities. IDU is responsible for a significant portion of new and existing HIV/AIDS cases in many parts of the world. In the U.S., the prevalence of HIV and hepatitis C virus is higher among populations of African-American and Latino injection drug users (IDUs) than among white IDUs. Methadone maintenance therapy (MMT) has been demonstrated to effectively reduce opiate use, HIV risk behaviors and transmission, general mortality and criminal behavior, but opiate-dependent minorities are less likely to access MMT than whites. A better understanding of the obstacles minority IDUs face accessing treatment is needed to engage racial and ethnic disparities in IDU as well as drug-related morbidity and mortality. In this study, we explore knowledge, attitudes and beliefs about methadone among 53 out-of-treatment Latino and African-American IDUs in Providence, RI. Our findings suggest that negative perceptions of methadone persist among racial and ethnic minority IDUs in Providence, including beliefs that methadone is detrimental to health and that people should attempt to discontinue methadone treatment. Additional potential obstacles to entering methadone therapy include cost and the difficulty of regularly attending a methadone clinic as well as the belief that an individual on MMT is not abstinent from drugs. Substance use researchers and treatment professionals should engage minority communities, particularly Latino communities, in order to better understand the treatment needs of a diverse population, develop culturally appropriate MMT programs, and raise awareness of the benefits of MMT
Specific Class I HLA Supertypes but Not HLA Zygosity or Expression Are Associated with Outcomes following HLA-Matched Allogeneic Hematopoietic Cell Transplant: HLA Supertypes Impact Allogeneic HCT Outcomes
Maximizing the probability of antigen presentation to T cells through diversity in HLAs can enhance immune responsiveness and translate into improved clinical outcomes, as evidenced by the association of heterozygosity and supertypes at HLA class I loci with improved survival in patients with advanced solid tumors treated with immune checkpoint inhibitors. We investigated the impact of HLA heterozygosity, supertypes, and surface expression on outcomes in adult and pediatric patients with acute myeloid leukemia (AML), myelodysplastic syndrome, acute lymphoblastic leukemia, and non-Hodgkin lymphoma who underwent 8/8 HLA-matched, T cell replete, unrelated, allogeneic hematopoietic cell transplant (HCT) from 2000 to 2015 using patient data reported to the Center for International Blood and Marrow Transplant Research. HLA class I heterozygosity and HLA expression were not associated with overall survival, relapse, transplant-related mortality (TRM), disease-free survival (DFS), and acute graft-versus-host disease following HCT. The HLA-B62 supertype was associated with decreased TRM in the entire patient cohort (hazard ratio [HR], 0.79; 95% CI, 0.69 to 0.90; P = .00053). The HLA-B27 supertype was associated with worse DFS in patients with AML (HR = 1.21; 95% CI, 1.10 to 1.32; P = .00005). These findings suggest that the survival benefit of HLA heterozygosity seen in solid tumor patients receiving immune checkpoint inhibitors does not extend to patients undergoing allogeneic HCT. Certain HLA supertypes, however, are associated with TRM and DFS, suggesting that similarities in peptide presentation between supertype members play a role in these outcomes. Beyond implications for prognosis following HCT, these findings support the further investigation of these HLA supertypes and the specific immune peptides important for transplant outcomes
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