388 research outputs found
Dr. Seitchik’s AI Research and Writing Companion: A Student\u27s Handbook for Leveraging Technology
This guide is intended to be utilized by students to help them use AI to assist in research and to scaffold their writing. Instructors can use it, if they allow AI to be used in their classes, to assist students in their research and writing endeavors. Some screenshots have been redacted for copyright reasons. A paper using this guide is under review and a citation will be provided when available. The guide can assist anyone when writing, especially research papers, but it is geared toward a student population for use in or outside of the classroom
Spectroscopic Study of As and La NMR on Layered Structure Ferromagnet LaCoAsO
As and La field-swept NMR spectra were obtained for the novel
weakly itinerant ferromagnet LaCoAsO with 2D layered structure above the Curie
temperature of 55 K. By analyzing NMR spectra, temperature dependences of
Knight shift and nuclear quadrupole resonance frequency were
obtained successfully for each nucleus. We confirmed from the so-called
- plots that the macroscopic magnetization of our {LaCoAsO} powder
sample is intrinsic and does not contain the contribution from impurity phases.
We estimated hyperfine coupling constants from the slope of - plots
and compared to that of iron-arsenide superconductor.Comment: 5 pages, 5 figures, published on J. Phys. Soc. Jpn. at Vol.79,
pp.054703 (2010)
From One Job to the Next: Worker Adjustment in a Changing Labor Market
The authors discuss how the structure of job opportunities has changed over the last two decades; specifically the transfer of jobs from manufacturing to service industries. They then link these changes to issues of worker displacement policy and worker mobility.https://research.upjohn.org/up_press/1105/thumbnail.jp
Worker Adjustment in Perspective
The authors discuss how the structure of job opportunities has changed over the last two decades; specifically the transfer of jobs from manufacturing to service industries. They then link these changes to issues of worker displacement policy and worker mobility.https://research.upjohn.org/up_press/1105/thumbnail.jp
Enhancing Team Learning Experiences in the Classroom
There are many different and effective ways to introduce teams and team learning into the management classroom. This paper discusses different ways we incorporated group and team learning in the classroom using a variety of activities. From our initial student survey, we developed a measure of teamwork and independent learning. Our findings indicate that when students perceive a fair work distribution in their teams, they are also more team oriented than students who perceive an unfair work distribution. Suggestions for enhancements to team learning, and future ideas for research are discussed
Site-selective protein-modification chemistry for basic biology and drug development.
Nature has produced intricate machinery to covalently diversify the structure of proteins after their synthesis in the ribosome. In an attempt to mimic nature, chemists have developed a large set of reactions that enable post-expression modification of proteins at pre-determined sites. These reactions are now used to selectively install particular modifications on proteins for many biological and therapeutic applications. For example, they provide an opportunity to install post-translational modifications on proteins to determine their exact biological roles. Labelling of proteins in live cells with fluorescent dyes allows protein uptake and intracellular trafficking to be tracked and also enables physiological parameters to be measured optically. Through the conjugation of potent cytotoxicants to antibodies, novel anti-cancer drugs with improved efficacy and reduced side effects may be obtained. In this Perspective, we highlight the most exciting current and future applications of chemical site-selective protein modification and consider which hurdles still need to be overcome for more widespread use.We thank FCT Portugal (FCT Investigator to G.J.L.B.), the EU (Marie-Curie CIG to G.J.L.B. and Marie-Curie IEF to O.B.) and the EPSRC for funding. G.J.L.B. is a Royal Society University Research Fellow.This is the author accepted manuscript. The final version is available from NPG via http://dx.doi.org/10.1038/nchem.239
Bio-orthogonal Fluorescent Labelling of Biopolymers through Inverse-Electron-Demand Diels–Alder Reactions
Bio-ort
hogona
llabellin
gschemes
based
on inverse-elec
tron-
deman
dDiels–Ald
er (IEDDA)
cycloa
ddition
have
attracted
much
attention
in chem
ical biology
recently
.The appeal
ing
features
of this reactio
n, such
as the fast reactio
nkinetics,
fully
bio-ort
hogonal
nature
and high
selectiv
ity,have helped
chem
i-
cal biologists
gain
deeper
understandi
ng of biochemic
al pro-
cesses
at the molecular
level.Listing
the compo
nents
and dis-
cussing
the possib
ilities
andlimitations
of thesereagent
s, we
provid
earecent
snapshot
of the field
of IEDDA
-based
biomo-
lecular
manipulatio
nwith special
focus
on fluores
cent
modula-
tion
approaches
throug
hthe use of bio-orthogon
alized
build-
ing blocks.
At the end,
we discuss
challenges
that
need
to be
addres
sed
for further
develop
ments
in order
to overcome
recent
limita
tions
and to enabl
eresearchers
to answer
biomo
-
lecular
quest
ions in more
detail
- …
