Effect of silicate ions on electrode overvoltage

The influence of the addition of a silicate to a caustic solution (KOH) is studied in order to determine the degree to which silicates inhibit the corrosion of chrysotile under conditions of electrolysis at working temperatures of 100 C and above. In an alkaline solution containing various silicate concentrations, current density was increased and electrode overvoltage was measured. Results show that silicate ion concentrations in the electrolyte increase with temperature without effecting electrochemical performance up to 115 C at 700 MA/sqcm. At this point the concentration is about 0.5 g Si/100 g KOH. Beyond this limit, electrolytic performance rapidly degenerates due to severe oxidation of the electrodes

Distributed mobility management - framework & analysis

Mobile operators consider the distribution of mobility anchors to enable offloading some traffic from their core network. The Distributed Mobility Management (DMM) Working Group is investigating the impact of decentralized mobility management to existing protocol solutions, while taking into account well defined requirements, which are to be met by a future solution. This document discusses DMM using a functional framework. Functional Entities to support DMM as well as reference points between these Functional Entities are introduced and described. The described functional framework allows distribution and co-location of Functional Entities and build a DMM architecture that matches the architecture of available protocols. Such methodology eases the analysis of best current practices with regard to functional and protocol gaps

A systematic literature review of the human skin microbiome as biomarker for dermatological drug development

Aims: To explore the potential of the skin microbiome as biomarker in six dermatological conditions: atopic dermatitis (AD), acne vulgaris (AV), psoriasis vulgaris (PV), hidradenitis suppurativa (HS), seborrhoeic dermatitis/pityriasis capitis (SD/PC) and ulcus cruris (UC). Methods: A systematic literature review was conducted according to the PRISMA guidelines. Two investigators independently reviewed the included studies and ranked the suitability microbiome implementation for early phase clinical studies in an adapted GRADE method. Results: In total, 841 papers were identified and after screening of titles and abstracts for eligibility we identified 42 manuscripts that could be included in the review. Eleven studies were included for AD, five for AV, 10 for PV, two for HS, four for SD and 10 for UC. For AD and AV, multiple studies report the relationship between the skin microbiome, disease severity and clinical response to treatment. This is currently lacking for the remaining conditions. Conclusion: For two indications - AD and AV - there is preliminary evidence to support implementation of the skin microbiome as biomarkers in early phase clinical trials. For PV, UC, SD and HS there is insufficient evidence from the literature. More microbiome-directed prospective studies studying the effect of current treatments on the microbiome with special attention for patient meta-data, sampling methods and analysis methods are needed to draw more substantial conclusions

Analisis Produksi Sagu (Studi Kasus di Desa Hatunuru Kecamatan Taniwel Timur Kabupaten Seram Bagian Barat)

Sago trees, especially sago flour, have a high economic value. Various snacks made from sago flour are used as local foods such as sago tumang, papeda, and different cakes. This study aims to find out the economic value of sago production. Data collection method using interviews and direct surveys of 6 key informants who process sago. Primary and secondary data are analyzed qualitatively and quantitatively. The results showed that sago trees have economic value. The result of calculating the monetary value for the roof is ± Rp 304,660,000, sago tumang amounted to ± Rp 55,987,750 to ± Rp 68,808,250, and sago plate amounted to ± Rp 14,030,000 per year so that the total economic value of sago production of Rp 785,160,000 / year. Sago contributes to the economic improvement of the community and is a culture that is as a local food of the Moluccas that must continue to be preserved

INTRAVENOUS IMMUNOGLOBULIN INDUCES ANERGY STATELIKE OF AUTO-REACTIVE B LYMPHOCYTES IN SJÖGREN’S SYNDROME

Oral Communication presented at the ";Forum des Jeunes Chercheurs";, Brest (France) 2011

Introduction to skin aging

YesCutaneous science has seen considerable development in the last 25 years, in part due to the -Omics revolution, and the appreciation that this organ is hardwired into the body’s key neuroimmuno- endocrine axes. Moreover, there is greater appreciation of how stratification of skin disorders will permit more targeted and more effective treatments. Against this has been how the remarkable extension in the average human life-span, though in the West at least, this parallels worrying increases in lifestyle-associated conditions like diabetes, skin cancer etc. These demographic trends bring greater urgency to finding clinical solutions for numerous age-related deficits in skin function caused by extrinsic and intrinsic factors. Mechanisms for aging skin include the actions of reactive oxygen species (ROS), mtDNA mutations, and telomere shortening, as well as hormonal changes. We have also significantly improved our understanding of how to harness the skin’s considerable regenerative capacity e.g., via its remarkable investment of stem cell subpopulations. In this way we hope to develop new strategies to selectively target the skin’s capacity to undergo optimal wound repair and regeneration. Here, the unsung hero of the skin regenerative power may be the humble hair follicle, replete with its compliment of epithelial, mesenchymal, neural and other stem cells. This review introduces the topic of human skin aging, with a focus on how maintenance of function in this complex multi-cell type organ is key for retaining quality of life into old age

Is the meiofauna a good indicator for climate change and anthropogenic impacts?

Our planet is changing, and one of the most pressing challenges facing the scientific community revolves around understanding how ecological communities respond to global changes. From coastal to deep-sea ecosystems, ecologists are exploring new areas of research to find model organisms that help predict the future of life on our planet. Among the different categories of organisms, meiofauna offer several advantages for the study of marine benthic ecosystems. This paper reviews the advances in the study of meiofauna with regard to climate change and anthropogenic impacts. Four taxonomic groups are valuable for predicting global changes: foraminifers (especially calcareous forms), nematodes, copepods and ostracods. Environmental variables are fundamental in the interpretation of meiofaunal patterns and multistressor experiments are more informative than single stressor ones, revealing complex ecological and biological interactions. Global change has a general negative effect on meiofauna, with important consequences on benthic food webs. However, some meiofaunal species can be favoured by the extreme conditions induced by global change, as they can exhibit remarkable physiological adaptations. This review highlights the need to incorporate studies on taxonomy, genetics and function of meiofaunal taxa into global change impact research

An SDN-based Network Architecture for Extremely Dense Wireless Networks

Telecommunications networks are undergoing ma- jor changes so as to meet the requirements of the next gener- ation of users and services, which create a need for a general revised architectural approach rather than a series of local and incremental technology updates. This is especially manifest in mobile broadband wireless access, where a major traffic increase is expected, mostly because of video transmission and cloud-based applications. The installation of a high number of very small cells is foreseen as the only practical way to achieve the demands. However, this would create a struggle on the mobile network operators because of the limited backhaul capacity, the increased energy consumption, and the explosion of signalling. In the FP7 project CROWD, Software Defined Networking (SDN) has been identified as a solution to tame extreme density of wireless networks. Following this paradigm, a novel network architecture accounting for MAC control and Mobility Management has been proposed, being the subject of this paper.TRUEpu

Is the meiofauna a good indicator for climate change and anthropogenic impacts?

Our planet is changing, and one of the most pressing challenges facing the scientific community revolves around understanding how ecological communities respond to global changes. From coastal to deep-sea ecosystems, ecologists are exploring new areas of research to find model organisms that help predict the future of life on our planet. Among the different categories of organisms, meiofauna offer several advantages for the study of marine benthic ecosystems. This paper reviews the advances in the study of meiofauna with regard to climate change and anthropogenic impacts. Four taxonomic groups are valuable for predicting global changes: foraminifers (especially calcareous forms), nematodes, copepods and ostracods. Environmental variables are fundamental in the interpretation of meiofaunal patterns and multistressor experiments are more informative than single stressor ones, revealing complex ecological and biological interactions. Global change has a general negative effect on meiofauna, with important consequences on benthic food webs. However, some meiofaunal species can be favoured by the extreme conditions induced by global change, as they can exhibit remarkable physiological adaptations. This review highlights the need to incorporate studies on taxonomy, genetics and function of meiofaunal taxa into global change impact research