165 research outputs found

    Pendapatan Pengrajin Alumunium Untuk Memenuhi Kebutuhan Ekonomi Keluarga Di Desa Ohoitahit Kecematan Dullah Utara Kota Tual

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    Penelitian ini bertujuan untuk menganalisis pendapatan pengrajin alumunium di Desa Ohoitahit, Kecamatan Dullah Utara, Kota Tual, serta mengidentifikasi dampaknya terhadap kesejahteraan rumah tangga di wilayah tersebut. Metode deskriptif digunakan dalam penelitian ini dengan mengumpulkan data melalui wawancara, dokumentasi, dan observasi terhadap 20 responden yang merupakan pengrajin alumunium. Hasil penelitian menunjukkan bahwa industri rumah tangga kerajinan alumunium di Desa Ohoitahit memiliki potensi signifikan dalam meningkatkan ekonomi dan pemenuhan kebutuhan hidup masyarakat setempat. Kendati begitu, sektor ini juga menghadapi beberapa kendala seperti keterbatasan sumber daya manusia, peralatan sederhana, dan rendahnya kualitas dan kuantitas produk dibandingkan dengan standar industri. Peningkatan dukungan dari pemerintah dan pihak terkait diharapkan dapat membantu pengrajin sehingga sektor ini dapat memberikan kontribusi yang lebih besar terhadap perekonomian dan kesejahteraan masyarakat setempa

    Modified expression of alternative oxidase in transgenic tomato and petunia affects the level of tomato spotted wilt virus resistance

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    <p>Abstract</p> <p>Background</p> <p><it>Tomato spotted wilt virus </it>(TSWV) has a very wide host range, and is transmitted in a persistent manner by several species of thrips. These characteristics make this virus difficult to control. We show here that the over-expression of the mitochondrial alternative oxidase (AOX) in tomato and petunia is related to TSWV resistance.</p> <p>Results</p> <p>The open reading frame and full-length sequence of the tomato AOX gene <it>LeAox1au </it>were cloned and introduced into tomato 'Healani' and petunia 'Sheer Madness' using <it>Agrobacterium</it>-mediated transformation. Highly expressed AOX transgenic tomato and petunia plants were selfed and transgenic R1 seedlings from 10 tomato lines and 12 petunia lines were used for bioassay. For each assayed line, 22 to 32 tomato R1 progeny in three replications and 39 to 128 petunia progeny in 13 replications were challenged with TSWV. Enzyme-Linked Immunosorbent Assays showed that the TSWV levels in transgenic tomato line FKT4-1 was significantly lower than that of wild-type controls after challenge with TSWV. In addition, transgenic petunia line FKP10 showed significantly less lesion number and smaller lesion size than non-transgenic controls after inoculation by TSWV.</p> <p>Conclusion</p> <p>In all assayed transgenic tomato lines, a higher percentage of transgenic progeny had lower TSWV levels than non-transgenic plants after challenge with TSWV, and the significantly increased resistant levels of tomato and petunia lines identified in this study indicate that altered expression levels of AOX in tomato and petunia can affect the levels of TSWV resistance.</p

    Natural occurrence of Cucumber mosaic virus infecting water mint (Mentha aquatica) in Antalya and Konya, Turkey

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    A virus causing a disease in mint (the aromatic and culinary plant) has recently become a problem in the Taurus Mountains, a mountain range in the Mediterranean region of Turkey. To detect the virus and investigate its distribution in the region, mint leaf samples were collected from the vicinity of spring areas in the plateaus of Antalya and Konya in 2009. It was found that Cucumber mosaic virus (CMV) was detected in 27.08% of symptomatic samples tested by DAS-ELISA. To the best of our knowledge, this is the first report of CMV on mint plants in this region of Turkey

    Pasientoverganger - en utfordring for kvalitet og pasientsikkerhet

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    Bakgrunn og hensikt: Nasjonale handlingsplaner og stortingsmeldinger viser at pasientoverganger er et område med stort forbedringspotensial. Når eldre pasienter overføres mellom tjenesteledd er det flere utfordringer knyttet til tjenestenes kvalitet, og pasientsikkerheten utfordres i særlig stor grad. Samhandlingsreformen presiserer at samhandling mellom tjenesteledd bør være et av helse- og omsorgssektorens viktigste utviklingsområder, for å sikre helhetlige og koordinerte tjenestetilbud som ivaretar pasientens behov. Hensikten med oppgaven er å belyse utfordringer knyttet til pasientoverganger mellom somatisk sykehus og hjemmetjeneste. Videre er hensikten å undersøke hvordan sykepleier kan ivareta kvalitet og pasientsikkerhet ved pasientoverganger. Metode: Et litteraturstudium gjennomført våren 2023, basert på åtte forskningsartikler. Annen relevant faglitteratur og forskning er inkludert som støtte til oppgaven. Resultater: Resultatene viser at det eksisterer flere utfordringer knyttet til pasientsikkerhet og kvalitet ved pasientoverganger. Funnene i studien viser hvordan sykepleier kan ivareta pasientsikkerhet og kvalitet og er inndelt i fire hovedtema: informasjonsoverføring, inkludering av pasient og pårørende, sykepleier som koordinator og kompetanse og opplæring. Konklusjon: Sykepleier har en nøkkelrolle ved koordinering av pasientoverganger. Sykepleiers ivaretakelse av pasientsikkerhet og kvalitet, gjenspeiles i en praksis hvor sykepleier sikrer god kommunikasjon, involverer pasienter og pårørende og har tilstrekkelig kompetanse. Litteraturstudien aktualiserer viktigheten av tematikken i dag og for fremtiden.Background and aim: National action plans and parliamentary notices indicates the need for improvement in care transitions. For elderly patients these transitions challenges patient safety and quality. The coordination reform emphasizes the need for coordination between service levels as a vital area of development, ensuring comprehensive and coordinated services tailored to the patient’s needs. The thesis aims to address challenges in care transitions between somatic hospital and home health care and to examine how nurses can safeguard quality and patient safety during these transitions. Method: A literature study conducted in spring of 2023, based on eight research articles, along with other relevant literature and research to support the thesis. Results: The study revealed challenges impacting patient safety and quality during care transitions. The findings demonstrated how nurses can safeguard patient safety and quality encompassing four main themes: information transfer, inclusion of patients and next of kin, coordinating nurse, and competence and training. Conclusion: Nurses are vital in coordinating care transitions. Nurses' safeguarding of patient safety and quality is reflected in a practice where nurses ensure good communication, involve patients and next of kin and have enough competence. This study emphasizes the relevance of the topic in the present and future

    The effect of marine n-3 polyunsaturated fatty acids on heart rate variability in renal transplant recipients:a randomized controlled trial

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    Resting heart rate (rHR) and heart rate variability (HRV) are non-invasive measurements that predict the risk of sudden cardiac death (SCD). Marine n-3 polyunsaturated fatty acid (PUFA) supplementation may decrease rHR, increase HRV, and reduce the risk of SCD. To date, no studies have investigated the effect of marine n-3 PUFA on HRV in renal transplant recipients. In a randomized controlled trial, 132 renal transplant recipients were randomized to receive either three 1 g capsules of marine n-3 PUFA, each containing 460 mg/g EPA and 380 mg/g DHA, or control (olive oil) for 44 weeks. HRV was calculated in the time and frequency domains during a conventional cardiovascular reflex test (response to standing, deep breathing, and Valsalva maneuver) and during 2 min of resting in the supine position. There was no significant effect of marine n-3 PUFA supplementation on time-domain HRV compared with controls. rHR decreased 3.1 bpm (± 13.1) for patients receiving marine n-3 PUFA compared to 0.8 (± 11.0) in controls (p = 0.28). In the frequency domain HRV analyses, there was a significant change in response to standing in both high and low frequency measures, 2.9 (p = 0.04, 95% CI (1.1;8)) and 2.7 (p = 0.04, 95% CI (1.1;6.5)), respectively. In conclusion, 44 weeks of supplemental marine n-3 PUFAs in renal transplant recipients significantly improved the cardiac autonomic function, assessed by measuring HRV during conventional cardiovascular reflex tests

    Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese

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    <p>Abstract</p> <p>Background</p> <p>Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the <it>MMP1 </it>gene was found significantly affecting promoter activity and corresponding transcription level. Hence it is a good candidate for genetic studies in DDD.</p> <p>Methods</p> <p>Southern Chinese volunteers between 18 and 55 years were recruited from the population. DDD in the lumbar spine was defined by MRI using Schneiderman's classification. Genomic DNA was isolated from the leukocytes and genotyping was performed using the Sequenom<sup>® </sup>platform. Association and Hardy-Weinberg equilibrium checking were assessed by Chi-square test and Mann-Whitney U test.</p> <p>Results</p> <p>Our results showed substantial evidence of association between -1607 promoter polymorphism of <it>MMP1 </it>and DDD in the Southern Chinese subjects. D allelic was significantly associated with DDD (p value = 0.027, odds ratio = 1.41 with 95% CI = 1.04–1.90) while Genotypic association on the presence of D allele was also significantly associated with DDD (p value = 0.046, odds ratio = 1.50 with 95% CI = 1.01–2.24). Further age stratification showed significant genotypic as well as allelic association in the group of over 40 years (genotypic: p value = 0.035, odds ratio = 1.617 with 95% CI = 1.033–2.529; allelic: p value = 0.033, odds ratio = 1.445 with 95% CI = 1.029–2.029). Disc bulge, annular tears and the Schmorl's nodes were not associated with the D allele.</p> <p>Conclusion</p> <p>We demonstrated that individuals with the presence of D allele for the -1607 promoter polymorphism of <it>MMP1 </it>are about 1.5 times more susceptible to develop DDD when compared with those having G allele only. Further association was identified in individuals over 40 years of age. Disc bulge, annular tear as well as Schmorl's nodes were not associated with this polymorphism.</p
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