158 research outputs found

    Enhancing The Learning Environment Of Nursing Students Through Interprofessional Collaboration

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    The AACN position statement (1999) supports interprofessional collaboration. The development of innovative collaborative teaching methods within education may enhance the learning environment of students. Educational institutions utilize student evaluations as a method of listening to the voices of students, but research related to their use is limited. The purpose of this study was to explore the impact of interprofessional collaboration on nursing students’ perceptions of the online learning environment. An innovative collaborative teaching methodology was developed using a variety of disciplines, including physicians, pharmacists, chiropractic physicians, and nurses. Quantitative data analyses indicated a significant increase in student satisfaction with the online course as well as the online environment p < 0.05 following the establishment of the collaborative teaching methodology. Qualitative analysis illustrated enhanced satisfaction among students following the institution of interprofessional collaboration. Findings that view the learning environment through the lens of students’ eyes have many implications, including increased student and faculty satisfaction with the teaching/learning experience and enhanced collaboration among healthcare professionals. In addition, results may impact the curriculum by identifying a multidisciplinary approach to nursing education as an important resource. If we believe that students have a right to be active participants in their educational experiences, then we must give voice to their values, choices, concerns, and requests. A collaborative teaching methodology is one way to ensure that students’ voices are heard and acted upon, and it was found to be an innovative solution in meeting enrollment demands and healthcare needs. Collaborative relationships within nursing practice and nursing education are essential in the preparation of future nurses.

    Enhancing the learning environment of nursing students through interprofessional collaboration

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    Session presented on: Friday, July 26, 2013: Purpose: Interprofessional collaboration is supported by the AACN position statement (1999). The development of innovative collaborative teaching methods within education may enhance the learning environment of students. The purpose of this research study was to explore the impact of interprofessional collaboration on nursing students\u27 perceptions of the online learning environment. An innovative collaborative teaching methodology was developed using a variety of disciplines including physicians, pharmacists, chiropractic physicians, and nurses. Methods: The faculty utilized a multidisciplinary approach to education bringing the gift of each person\u27s expertise to the learning environment while studying pathophysiology. 500 student evaluations were completed upon completion of the pathophysiology course. An integrative methodology using a quantitative descriptive and an experimental correlational design formed the basis for the quantitative aspect of this study. Qualitative analysis revealed major themes identifying enhanced satisfaction among students following the institution of interprofessional collaboration. Results: Findings which view the learning environment through the lens of students\u27 eyes have many implications including enhanced collaboration among healthcare professionals, and increased student and faculty satisfaction with the teaching learning experience. Results may impact the curriculum by identifying a multidisciplinary approach to nursing education as an important resource. Conclusion: If we believe that students have a right to be active participants in their educational experiences, then we must give voice to their values, choices, concerns and requests. A collaborative teaching paradigm is only one way to ensure that students\u27 voices are heard and acted upon but was found to be an effective tool

    Republicanism and Markets

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    The republican tradition has long been ambivalent about markets and commercial society more generally: from the contrasting positions of Rousseau and Smith in the eighteenth century to recent neorepublican debates about capitalism, republicans have staked out diverse positions on fundamental issues of political economy. Rather than offering a systematic historical survey of these discussions, this chapter will instead focus on the leading neo-republican theory—that of Philip Pettit—and consider its implications for market society. As I will argue, Pettit’s theory is even friendlier to markets than most have believed: far from condemning commercial society, his theory recognizes that competitive markets and their institutional preconditions are an alternative means to limit arbitrary power across the domestic, economic, and even political spheres. While most republican theorists have focused on political means to limit such power—including both constitutional means (e.g., separation of powers, judicial review, the rule of law, federalism) and participatory ones (democratic elections and oversight)—I will examine here an economic model of republicanism that can complement, substitute for, and at times displace the standard political model. Whether we look at spousal markets, labor markets, or residential markets within federal systems, state policies that heighten competition among their participants and resource exit from abusive relationships within them can advance freedom as non-domination as effectively or even more effectively than social-democratic approaches that have recently gained enthusiasts among republicans. These conclusions suggest that democracy, be it social or political, is just one means among others for restraining arbitrary power and is consequently less central to (certain versions of) republicanism than we may have expected. So long as they counteract domination, economic inroads into notionally democratic territory are no more worrisome than constitutional ones

    Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

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    Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

    A signalome screening approach in the autoinflammatory disease TNF Receptor Associated Periodic Syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing

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    TNF Receptor Associated Periodic Syndrome (TRAPS) is an autoinflammatory disease caused by mutations in TNF Receptor 1 (TNFR1). Current therapies for TRAPS are limited and do not target the pro-inflammatory signalling pathways that are central to the disease mechanism. Our aim was to identify drugs for repurposing as anti-inflammatories based on their ability to down-regulate molecules associated with inflammatory signalling pathways that are activated in TRAPS. This was achieved using rigorously optimised, high through- put cell culture and reverse phase protein microarray systems to screen compounds for their effects on the TRAPS-associated inflammatory signalome. 1360 approved, publically available, pharmacologically active substances were investigated for their effects on 40 signalling molecules associated with pro-inflammatory signalling pathways that are constitutively upregulated in TRAPS. The drugs were screened at four ten-fold concentrations on cell lines expressing both wild-type (WT) TNFR1 and TRAPS-associated C33Y mutant TNFR1, or WT TNFR1 alone; signalling molecule levels were then determined in cell lysates by the reverse phase protein microarray. A novel mathematical methodology was developed to rank the compounds for their ability to reduce the expression of signalling molecules in the C33Y-TNFR1 transfectants towards the level seen in the WT-TNFR1 transfectants. Seven high-ranking drugs were selected and tested by RPPA for effects on the same 40 signalling molecules in lysates of peripheral blood mononuclear cells (PBMCs) from C33Y-TRAPS patients compared to PBMCs from normal controls. The fluoroquinolone antibiotic lomefloxacin, as well as others from this class of compounds, showed the most significant effects on multiple pro-inflammatory signalling pathways that are constitutively activated in TRAPS; lomefloxacin dose-dependently significantly reduced expression of 7/40 signalling molecules across the Jak/Stat, MAPK, NF-kB and PI3K/AKT pathways. This study demonstrates the power of signalome screening for identifying candidates for drug repurposing

    The state of the Martian climate

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    60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

    Application of the LymphGen classification tool to 928 clinically and genetically-characterised cases of diffuse large B cell lymphoma (DLBCL).

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    We recently published results of targeted sequencing applied to 928 unselected cases of DLBCL registered in the Haematological Malignancy Research Network (HMRN) registry (1). Clustering allowed us to resolve five genomic subtypes. These subtypes shared considerable overlap with those proposed in two independent genomic studies(2, 3), suggesting the potential to use genetics to stratify patients by both risk and biology. In the original studies, clustering techniques were applied to sample cohorts to reveal molecular substructure, but left open the challenge of how to classify an individual patient. This was addressed by the LymphGen classification tool (4). LymphGen assigns an individual case to one of six molecular subtypes. The tool accommodates data from exome or targeted sequencing, either with or without copy number variant (CNV) data. Separate gene expression data allows classification of a seventh, MYC-driven subtype defined by a double hit (DHL) or molecular high-grade (MHG) gene expression signature(5-7).HR was funded by a studentship from the Medical Research Council. DH was supported by a Clinician Scientist Fellowship from the Medical Research Council (MR/M008584/1). The Hodson laboratory receives core funding from Wellcome and MRC to the Wellcome-MRC Cambridge Stem Cell Institute and core funding from the CRUK Cambridge Cancer Centre. HMRN is supported by BCUK 15037 and CRUK 18362

    Micromechanical Properties of Injection-Molded Starch–Wood Particle Composites

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    The micromechanical properties of injection molded starch–wood particle composites were investigated as a function of particle content and humidity conditions. The composite materials were characterized by scanning electron microscopy and X-ray diffraction methods. The microhardness of the composites was shown to increase notably with the concentration of the wood particles. In addition,creep behavior under the indenter and temperature dependence were evaluated in terms of the independent contribution of the starch matrix and the wood microparticles to the hardness value. The influence of drying time on the density and weight uptake of the injection-molded composites was highlighted. The results revealed the role of the mechanism of water evaporation, showing that the dependence of water uptake and temperature was greater for the starch–wood composites than for the pure starch sample. Experiments performed during the drying process at 70°C indicated that the wood in the starch composites did not prevent water loss from the samples.Peer reviewe
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