シリコンの固液界面キネティクス

Tohoku University博士（理学）thesi

Predicting wealth score from remote sensing satellite images and household survey data using deep learning

The most exigent call of the United Nations’ 17 sustainable goals is to end poverty everywhere by 2030. Unlike in the past, when poverty was measured based on data collected through ground-level surveys, the new technology adopted by many developing and developed countries is to estimate the poverty index using remote sensing satellite images with the help of machine learning techniques. Our approach demonstrates the prediction of cluster wealth score and establishes the relationship between wealth score obtained from Demographic and Health Survey (DHS) data and remote sensing satellite images of India by calculating Pearson’s correlation coefficient (r2). The implementation results have been analyzed in four phases. Phase 1 comprises four regression models (RMs): Ridge, RANSAC, Lasso, and k-nearest neighbor for feature extraction from a pre-trained convolutional neural network model using daylight & nightlight images. Here, the Lasso RM outperforms the others and is best suited for predicting the wealth score. Phase 2 categorizes daylight images with DHS data, where the Lasso RM efficiently generates the cluster wealth score. Phase 3 focuses on images of specific regions of Delhi, Tamil Nadu, Maharashtra and Telangana, using the Lasso RM, as it emerged as the best predictor of cluster wealth score in the previous two phases. Phase 4 compares the results attained through our proposed model with existing result

In Vivo Toxicity Study of Ethanolic Extracts of Evolvulus alsinoides & Centella asiatica in Swiss Albino Mice

AIM: We aimed to investigate several parameters after the in vivo acute and sub-acute administration of ethanolic extracts from E. alsinoides & C. asiatica. METHODS: Malignant Ovarian Germ Cell Tumors for in vivo toxicity study guidelines 423 and 407 of Organization for Economic Co-operation and Development (OECD) were followed for acute and sub-acute toxicity assays respectively. For LD50 evaluation, a single dose of ethanolic extracts of Evolvulus alsinoides L. (EEA) and ethanolic extracts of Centella asiatica (ECA) was orally administered to mice at doses of 200, 400, 800, 1600 and 2000 mg/kg. Then the animals were observed for 72 hours. For acute toxicity evaluation, a single dose of both extracts was orally administered to mice at doses of 300, 600, 1200 and 2000 mg/kg and the animals were observed for 14 days. In the sub-acute study, the extracts were orally administered to mice for 28 days at doses of 300, 600, 1200 and 2000 mg/kg. To assess the toxicological effects, animals were closely observed on general behaviour, clinical signs of toxicity, body weight, food and water intake. At the end of the study, it was performed biochemical and hematological evaluations, as well as histopathological analysis from the following organs: brain, heart, liver, and kidney. RESULTS: The oral administration of E. alsinoides and C. asiatica ethanolic extracts, i.e. EEA 300, EEA 600, EEA 1200, EEA 2000, ECA 300, ECA 600, ECA 1200 & ECA 2000 mg/kg doses showed no moral toxicity effect in LD50, acute and sub-acute toxicity parameters. CONCLUSION: In this study, we had found that E. alsinoides & C. asiatica extract at different doses cause no mortality in acute and sub-acute toxicity study. Also, histopathology of kidney, liver, heart, and brain showed no alterations in tissues morphology

Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice

AIM: To carry out the comparative nootropic, neuroprotective potentials of two medicinal plant species. MATERIAL AND METHODS: For neuroprotective activity; behavior models (elevated plus maze & morris water maze), in vivo antioxidant (superoxide dismutase, catalase, lipid peroxidation & reduced glutathione), inflammatory markers (IL-1β, IL-6 & TNF-α) and acetylcholine esterase (AChE) assessment procedures followed at different dosages i.e. 250 & 500 mg/kg of Evolvulus alsinoides and Centella asiatica ethanolic extracts. At the end of the study, it was performed histopathological analysis of the following organs: brain, heart, liver, and kidney. RESULTS: In oral administration of different doses of ethanolic extracts of both medicinal plants i.e. Sco + EEA 250 = 2.49 ± 0.29 , Sco + EEA 500 = 2.67 ± 0.36, Sco + ECA 250 = 2.33 ± 0.17, Sco + ECA 500 = 2.77 ± 0.21, Sco + EEA + ECA 250 = 2.61 ± 0.32 and Sco + EEA + ECA 500 = 2.79 ± 0.16 U/mg of protein respectively against the scopolamine induced group Sco (control) = 5.51 ± 0.35 U/mg of protein extracts shows neuroprotective and nootropic activity with reducing AChE level in the brain homogenate of swiss albino mice. CONCLUSION: Since the E. alsinoides & C. asiatica are already used in traditional Indian medicine as the neuroprotective agent and also found promising effects over inflammatory diseases, wound healing, and immunomodulatory activity. The neuroprotective effect of both plants extracts attributed to inhibition of AChE activity and improve the spatial memory formation

PREVALENCE OF INTESTINAL PARASITIC INFESTATION AND ITS ASSOCIATED RISK FACTOR IN RURAL AREAS CHILDREN OF VARANASI DISTRICT, UTTAR PRADESH

Intestinal parasitic infection is a major cause of morbidity among young children in India, due to low socioeconomic status and poor personal hygiene practices. Intestinal parasitic infestations are majorly challenged by the rural areas school children of Varanasi district. Considering the fact, the current study was conducted among rural areas school children from 06-16 years of age, with an aim to know the prevalence of Intestinal worm infestation. The study was conducted on 246 school children's fecal specimens. The collected specimens were examined with the Saline wet mount and Iodine wet mount method. Out of the total studied subjects, the prevalence of Intestinal worm infestation was found to be 17%. In our study, Protozoan infections are 8% commonly found followed by Helminthic infection (Ascaris lumbricoides 4%, Hookworm 3%, H. nana 2%,) in the study participants. Worm infestation association was found to be statistically signicant and to rule out the status of nutrition and hygiene practices. Anemia is a major health issue in children of growing age in our country which causes high morbidity and mortality rate. Besides this helminthic infection in children is also a common problem due to unhygienic habitat. Hence the policy of iron and folic acid supplementation and the anti-helminthic drug should be administered globally as recommended by WHO may be practically enforced besides health and hygiene education.</jats:p