Research of Probability Symmetric Allocation Storage in Distributed Storage System

The goal of optimal allocation is to increase the stored data availability subject to minimize the storage budget. The symmetric allocation based on the network coding is proved to be optimal without considering the nodes availability in distributed storage system. Because of network conditions and node inherent property, each node has different availability. This paper focuses on the optimization distributed data storage problem with nodes availability. Based on probability model of storage system, we re-define the symmetric allocation as the probability symmetric allocation, and proposed probability symmetric allocation model and strategy which are proved to be optimal in the general condition based on SVM. Comparing to the symmetric allocation proposed by Leong D. et al., The proposed probability symmetric allocation scheme improves the data availability, and is more practical method for distributed storage system. DOI : http://dx.doi.org/10.11591/telkomnika.v12i5.510

Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction

Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal action, but their exact mechanism(s) of action is not clear. In the present study, we observed that n-6 PUFA linoleic acid (LA) inhibited tumor cell growth at high concentrations (above 300 μM); while low concentrations (100-200 μM) promoted proliferation. Analysis of cell mitochondrial membrane potential, reactive oxygen species (ROS) formation, malondialdehyde (MDA) accumulation and superoxide dismutase (SOD) activity suggested that anti-cancer action of LA is due to enhanced ROS generation and decreased cell anti-oxidant capacity that resulted in mitochondrial damage. Of the three cell lines tested, semi-differentiated colorectal cancer cells RKO were most sensitive to the cytotoxic action of LA, followed by undifferentiated colorectal cancer cell line (LOVO) while the normal human umbilical vein endothelial cells (HUVEC) were the most resistant (the degree of sensitivity to LA is as follows: RKO > LOVO > HUVEC). LA induced cell death was primed by mitochondrial apoptotic pathway. Pre-incubation of cancer cells with 100 μM LA for 24 hr enhanced sensitivity of differentiated and semi-differentiated cells to the subsequent exposure to LA. The relative resistance of LOVO cells to the cytotoxic action of LA is due to a reduction in the activation of caspase-3. Thus, LA induced cancer cell apoptosis by enhancing cellular oxidant status and inducing mitochondrial dysfunction

Surprising Performances of Students with Autism in Classroom with NAO Robot

Autism is a developmental disorder that manifests in early childhood and persists throughout life, profoundly affecting social behavior and hindering the acquisition of learning and social skills in those diagnosed. As technological advancements progress, an increasing array of technologies is being utilized to support the education of students with Autism Spectrum Disorder (ASD), aiming to improve their educational outcomes and social capabilities. Numerous studies on autism intervention have highlighted the effectiveness of social robots in behavioral treatments. However, research on the integration of social robots into classroom settings for children with autism remains sparse. This paper describes the design and implementation of a group experiment in a collective classroom setting mediated by the NAO robot. The experiment involved special education teachers and the NAO robot collaboratively conducting classroom activities, aiming to foster a dynamic learning environment through interactions among teachers, the robot, and students. Conducted in a special education school, this experiment served as a foundational study in anticipation of extended robot-assisted classroom sessions. Data from the experiment suggest that ASD students in classrooms equipped with the NAO robot exhibited notably better performance compared to those in regular classrooms. The humanoid features and body language of the NAO robot captivated the students\u27 attention, particularly during talent shows and command tasks, where students demonstrated heightened engagement and a decrease in stereotypical repetitive behaviors and irrelevant minor movements commonly observed in regular settings. Our preliminary findings indicate that the NAO robot significantly enhances focus and classroom engagement among students with ASD, potentially improving educational performance and fostering better social behaviors