1,446 research outputs found
Impact and puncture resistant material protects parts from damage
Uniform sized, laminated panels protect delicate parts and equipment from damage during storage and transportation. The panels consist of sheets of steel foil bonded between sheets of elastic foam. They are lightweight, impact and puncture-resistant, and, when formed into an enclosure, provide a barrier against moisture and thermal shock
Constrictive pericarditis in a post–renal transplant patient: a case report
INTRODUCTION: Constrictive pericarditis is a rare complication in the post–renal transplant period. It poses a diagnostic dilemma even in the modern era. Its incidence is not known and tuberculosis is implicated in some of the cases. CASE PRESENTATION: A 54-year-old Sri Lankan man, in the sixth year of transplant presented with resistant ascites, shortness of breath and elevated creatinine from the baseline. Pre-transplant he was empirically treated for tuberculosis pericarditis and was on isoniazid prophylaxis for 1 year following transplantation. Two-dimensional echocardiography and cardiac catheterization confirmed the diagnosis, and pericardiectomy was performed, which resulted in full resolution of the symptoms as well as the graft function. The histology or bacteriology failed to demonstrate features suggestive of tuberculosis in the surgical specimen. CONCLUSION: In constrictive pericarditis, a causative factor is difficult to find. Isoniazid prophylaxis shows benefit in preventing tuberculosis-associated constrictive pericarditis
Superconductor strip with transport current: Magneto-optical study of current distribution and its relaxation
The dynamics of magnetic flux distributions across a YBaCuO strip carrying
transport current is measured using magneto-optical imaging at 20 K. The
current is applied in pulses of 40-5000 ms duration and magnitude close to the
critical one, 5.5 A. During the pulse some extra flux usually penetrates the
strip, so the local field increases in magnitude. When the strip is initially
penetrated by flux, the local field either increases or decreases depending
both on the spatial coordinate and the current magnitude. Meanwhile, the
current density always tends to redistribute more uniformly. Despite the
relaxation, all distributions remain qualitatively similar to the Bean model
predictions.Comment: RevTeX, 9 pages, 9 figures, submitted to Supercond. Sci. Technol.
Revision: MO image and more refs are adde
Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource Limited Setting in Tanzania: A Case Report, Clinical Discussion and Brief Review of Existing Literature.
Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor obstetric care and scarcity of diagnostic and therapeutic resources available. A 37 year old African female presented ten years post partum with features of multiple endocrine deficiencies including hypothyroidism, hypoadrenalism, lactation failure and secondary amenorrhea. In addition she had clinical features of an underlying autoimmune condition. These included a history of post-partum thyroiditis, alopecia areata, livedo reticularis and deranged coagulation indices. A remarkable clinical response followed appropriate hormone replacement therapy including steroids. This constellation has never been reported before; we therefore present an interesting clinical discussion including a brief review of existing literature. Post partum pituitary insufficiency is an under-reported condition of immense clinical importance especially in the developing world. A high clinical index of suspicion is vital to ensure an early and correct diagnosis which will have a direct bearing on management and patient outcome
Current density inhomogeneity throughout the thickness of superconducting films and its effect on their irreversible magnetic properties
We calculate the distribution of the current density in superconducting
films along the direction of an external field applied perpendicular to the
film plane. Our analysis reveals that in the presence of bulk pinning is
inhomogeneous on a length scale of order the inter vortex distance. This
inhomogeneity is significantly enhanced in the presence of surface pinning. We
introduce new critical state model, which takes into account the current
density variations throughout the film thickness, and show how these variations
give rise to the experimentally observed thickness dependence of and
magnetic relaxation rate.Comment: RevTex, 9 PS figures. To appear in Phys. Rev.
Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.
Myeloproliferative neoplasms (MPN), which overproduce blood cells in the bone marrow, have recently been linked with a genetically determined decrease in expression of the MYB transcription factor. Here, we use a mouse MYB knockdown model with an MPN-like phenotype to show how lower levels of MYB lead to stem cell characteristics in myeloid progenitors. The altered progenitor properties feature elevated cytokine responsiveness, especially to IL-3, which results from increased receptor expression and increased MAPK activity leading to enhanced phosphorylation of a key regulator of protein synthesis, ribosomal protein S6. MYB acts on MAPK signaling by directly regulating transcription of the gene encoding the negative modulator SPRY2. This mechanistic insight points to pathways that might be targeted therapeutically in MPN.Leukemia accepted article preview online, 17 October 2016. doi:10.1038/leu.2016.289
- …
