Multi-Layer Electrical Impedance Tomography Based Soft Tactile Skins

Distributed high-density tactile sensing is a challenging problem with numerous commercial applications. Soft sensing technologies appear to be a promising approach to address this challenge. In particular, Electrical Impedance Tomography (EIT)-based soft sensors are desirable because they can offer a large sensing surface without rigid electrodes and provide high sensing resolution. However, their applicability is limited to simple sensor shapes, and they require materials with high conductivity for sensing accuracy. This project introduces a novel multi-layered architecture for EIT-based soft skins. This innovation allows us to develop sensory skins with multiple materials and provides greater flexibility in electrode placement, resulting in higher accuracy. We experimentally tested the method's applicability using soft skins of varying morphology, employing a hydrogel-based tactile skin. The results demonstrate that our multi-layer soft skin improves average accuracy compared to a single-layer EIT-based skin, reducing it from 15.8 mm to 4.4 mm

Brain Training Game Improves Executive Functions and Processing Speed in the Elderly: A Randomized Controlled Trial

The beneficial effects of brain training games are expected to transfer to other cognitive functions, but these beneficial effects are poorly understood. Here we investigate the impact of the brain training game (Brain Age) on cognitive functions in the elderly.Thirty-two elderly volunteers were recruited through an advertisement in the local newspaper and randomly assigned to either of two game groups (Brain Age, Tetris). This study was completed by 14 of the 16 members in the Brain Age group and 14 of the 16 members in the Tetris group. To maximize the benefit of the interventions, all participants were non-gamers who reported playing less than one hour of video games per week over the past 2 years. Participants in both the Brain Age and the Tetris groups played their game for about 15 minutes per day, at least 5 days per week, for 4 weeks. Each group played for a total of about 20 days. Measures of the cognitive functions were conducted before and after training. Measures of the cognitive functions fell into four categories (global cognitive status, executive functions, attention, and processing speed). Results showed that the effects of the brain training game were transferred to executive functions and to processing speed. However, the brain training game showed no transfer effect on any global cognitive status nor attention.Our results showed that playing Brain Age for 4 weeks could lead to improve cognitive functions (executive functions and processing speed) in the elderly. This result indicated that there is a possibility which the elderly could improve executive functions and processing speed in short term training. The results need replication in large samples. Long-term effects and relevance for every-day functioning remain uncertain as yet.UMIN Clinical Trial Registry 000002825

Serum Wisteria Floribunda Agglutinin-Positive Mac-2 Binding Protein Values Predict the Development of Hepatocellular Carcinoma among Patients with Chronic Hepatitis C after Sustained Virological Response

Measurement of Wisteria floribundaagglutinin-positive human Mac-2 binding protein (WFA+-M2BP) in serum was recently shown to be a noninvasive method to assess liver fibrosis. The aim of this study was to evaluate the utility of serum WFA+-M2BP values to predict the development of hepatocellular carcinoma (HCC) in patients who achieved a sustained virological response (SVR) by interferon treatment. For this purpose, we retrospectively analyzed 238 patients with SVR who were treated with interferon in our department. Serum WFA+-M2BP values were measured at pre-treatment (pre-Tx), post-treatment (24 weeks after completion of interferon; post-Tx), the time of HCC diagnosis, and the last clinical visit. Of 238 patients with SVR, HCC developed in 16 (6.8%) patients. The average follow-up period was 9.1 years. The cumulative incidence of HCC was 3.4% at 5 years and 7.5% at 10 years. The median pre-Tx and post-Tx WFA+-M2BP values were 1.69 (range: 0.28 to 12.04 cutoff index (COI)) and 0.80 (range: 0.17 to 5.29 COI), respectively. The WFA+-M2BP values decreased significantly after SVR (P 60 years), sex (male), pre-Tx platelet count ( 2.0 COI) were associated with the development of HCC after SVR. Conclusion: Post-Tx WFA+-M2BP (> 2.0 COI) is associated with the risk for development of HCC among patients with SVR. The WFA+-M2BP values could be a new predictor for HCC after SVR

Active suction cup actuated by ElectroHydroDynamics phenomenon

Designing and manufacturing actuators using soft materials are among the most important subjects for future robotics. In nature, animals made by soft tissues such as the octopus have attracted the attention of the robotics community in the last years. Suckers (or suction cups) are one of the most important and peculiar organs of the octopus body, giving it the ability to apply high forces on the external environment. The integration of suction cups in soft robots can enhance their ability to manipulate objects and interact with the environment similarly to what the octopus does. However, artificial suction cups are currently actuated using fluid pressure so most of them require external compressors, which will greatly increase the size of the soft robot. In this work, we proposed the use of the ElectroHydroDynamics (EHD) principle to actuate a suction cup. EHD is a fluidic phenomenon coupled with electrochemical reaction that can induce pressure through the application of a high-intensity electric field. We succeeded in developing a suction cup driven by EHD keeping the whole structure extremely simple, fabricated by using a 3D printer and a cutting plotter. We can control the adhesion of the suction cup by controlling the direction of the fluidic flow in our EHD pump. Thanks to a symmetrical arrangement of the electrodes, composed by plates parallel to the direction of the channel, we can change the direction of the flow by changing the sign of the applied voltage. We obtained the pressure of 643 Pa in one unit of EHD pump and pressure of 1428 Pa in five units of EHD pump applying 6 kV. The suction cup actuator was able to hold and release a 2.86 g piece of paper. We propose the soft actuator driven by the EHD pump, and expand the possibility to miniaturize the size of soft robots