A Study of the Effect of Treatment on the Clinical Profile, Pain, and Disability in Migraine Patients Seen in a Tertiary Hospital [Response to Letter]

Geetha Kandasamy,1 Dalia Almaghaslah,1 Mona Almanasef,1 Tahani Musleh Almeleebia,1 Khalid Orayj,1 Ayesha Siddiqua,1 Eman Shorog,1 Asma M Alshahrani,1 Kousalya Prabahar,2 Vinoth Prabhu Veeramani,2 Palanisamy Amirthalingam,2 Saleh Alqifari,2 Naif Alshahrani,3 Aram Hamad AlSaedi,4 Alhanouf A Alsaab,5 Fatimah Aljohani,6 M Yasmin Begum,7 Akhtar Atiya8 1Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia; 2Department of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk, Kingdom of Saudi Arabia; 3Department of Pharmacy, Ad Diriyah Hospital, Ministry of Health (MOH), Riyadh, 13717, Kingdom of Saudi Arabia; 4College of Medicine, Taibah University, Al Madinah Al Munawwarah, Saudi Arabia; 5Pharmacist at Abha International Private Hospital, Abha, Saudi Arabia; 6Pharmacist at Prince Sultan Armed Forces Hospital, Almadenah Almonwarah, Saudi Arabia; 7Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia; 8Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi ArabiaCorrespondence: Geetha Kandasamy, Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia, Email [email protected]

Applications of an Extended (′/)-Expansion Method to Find Exact Solutions of Nonlinear PDEs in Mathematical Physics

We construct the traveling wave solutions of the (1+1)-dimensional modified Benjamin-Bona-Mahony equation, the (2+1)-dimensional typical breaking soliton equation, the (1+1)-dimensional classical Boussinesq equations, and the (2+1)-dimensional Broer-Kaup-Kuperschmidt equations by using an extended (/)-expansion method, where G satisfies the second-order linear ordinary differential equation. By using this method, new exact solutions involving parameters, expressed by three types of functions which are hyperbolic, trigonometric and rational function solutions, are obtained. When the parameters are taken as special values, some solitary wave solutions are derived from the hyperbolic function solutions

The traveling wave solutions for nonlinear partial differential equations using the (G ′ G )-expansion method.

Abstract: In the present paper, we construct the traveling wave solutions involving parameters for some nonlinear evolution equations in mathematical physics via th

International Journal of Physical Sciences

Silver nanoparticles biogenic synthesized using an orange peel extract and their use as an anti-bacterial agen

The Impact of Physical Activity on Depression, Anxiety, and Stress during Pregnancy in Saudi Arabia: A Cross-Sectional Study

Background and Objective: This study aimed to explore the impact of physical activity on depression, anxiety, and stress among pregnant women in the Jazan region of Saudi Arabia. Materials and Methods: A descriptive cross-sectional study was conducted among pregnant women attending randomly selected prenatal clinics in primary healthcare hospitals in Jazan, Saudi Arabia. The calculated sample size was 350. Data were collected conveniently through a semi-structured questionnaire covering demographic details, pregnancy-related characteristics, physical activity assessed using the Pregnancy Physical Activity Questionnaire (PPAQ), and mental health parameters evaluated by the Depression, Anxiety, and Stress Scale-21 (DASS-21). The statistical analyses included descriptive statistics and Wilcoxon and Kruskal–Wallis rank sum tests, with significance levels set at p < 0.05. Results: The study involved 406 pregnant females. Nearly a third (31%) had a family history of depression, anxiety, or distress. The prevalence of depression, anxiety, and stress was 62.6%, 68.7%, and 38.4%, respectively. The mean sedentary, light, moderate, vigorous, and total energy expenditures were 1.512, 24.35, 22.32, 4.84, and 53.02 metabolic equivalent tasks/day. Anxious females exhibited higher light activity (median 24, p = 0.033), while stressed ones showed higher light (median 25, p = 0.039), moderate (median 20, p < 0.001), and vigorous activity (median 3, p < 0.001). A significant association was observed between total energy expenditure and stress levels (p < 0.001). Conclusions: This study underscores the importance of physical activity in managing depression, anxiety, and stress among pregnant women in Jazan, Saudi Arabia. The findings suggest a need for tailored interventions to promote physical activity to improve mental well-being during pregnancy

A Study of the Effect of Treatment On the Clinical Profile, Pain, and Disability in Migraine Patients Seen in a Tertiary Hospital

Geetha Kandasamy,1 Dalia Almaghaslah,1 Mona Almanasef,1 Tahani Musleh Almeleebia,1 Khalid Orayj,1 Ayesha Siddiqua,1 Eman Shorog,1 Asma M Alshahrani,1 Kousalya Prabahar,2 Vinoth Prabhu Veeramani,2 Palanisamy Amirthalingam,2 Saleh Alqifari,2 Naif Alshahrani,3 Aram Hamad AlSaedi,4 Alhanouf A Alsaab,5 Fatimah Aljohani,6 M Yasmin Begum,7 Akhtar Atiya8 1Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia; 2Department of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk, Kingdom of Saudi Arabia; 3Department of Pharmacy, Ad Diriyah Hospital, Ministry of Health (MOH), Riyadh, 13717, Kingdom of Saudi Arabia; 4College of Medicine, Taibah University, Al Madinah, Al Munawwarah, Saudi Arabia; 5Pharmacist at Abha International Private Hospital, Abha, Saudi Arabia; 6Pharmacist at Prince Sultan Armed Forces Hospital, Almadenah, Almonwarah, Saudi Arabia; 7Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia; 8Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi ArabiaCorrespondence: Geetha Kandasamy, Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia, Email [email protected]: Migraine is a disabling disease that poses a significant societal burden. Migraine is a major cause of disability. Migraine is the eighth leading disease-causing disability in the population.Objective: To study the clinical profile and measure the pain and migraine-related disability of patients with all types of migraine using the McGill pain assessment scale and Migraine Disability Assessment (MIDAS) before and after 3 months of effect on the medication.Methods: A Prospective-Cross sectional study was carried out in a multispecialty hospital with male and female patients between 18 and 65 years. The data were collected from the patients directly through the questionnaire of McGill pain assessment scale-short form (SF) and MIDAS, which was provided before and after the medication.&#x00A0Results: There were 165 subjects of which 52 were men and 113 were women. The mean age of all the subjects was 43 years. About 26.06% of the subjects had a family history of headaches. The scores of McGill pain and MIDAS assessment before and after medication were as follows: 0– 15 were 30.90% and 73.33%, Score 16– 30 were 54.54% and 18.18%, the score of 31– 45 were 14.54% and 7.87% of the subjects. MIDAS grade I was 17.57% and 50.90%, Grade II 33.93% and 21.81%, Grade III 30.30% and 15.75% Grade IV 18.18% and 11.51% of the subjects.Discussion: The calculated “t” value between the before and after medication values of McGill and MIDAS by paired ‘t-test was 13.85 and 17.49 respectively. As the calculated “t” value is more than the table value, the alternate hypothesis is accepted.Conclusion: This study confirms that there is a significant difference in disability levels before and after acute and preventative treatments when measured over 3 months. In addition, the preponderance of females was high, and the functional disability that affects work and social activity associated with migraine is moderate to severe.Keywords: migraine, pain, disability, loss of productivity, MIDA