Observation of sub-Doppler absorption in the /Lambda-type three-level Doppler-broadened cesium system

Thanks to the atomic coherence in coupling laser driven atomic system, sub-Doppler absorption has been observed in Doppler-broadened cesium vapor cell via the /Lambda-type three-level scheme. The linewidth of the sub-Doppler absorption peak become narrower while the frequency detuning of coupling laser increases. The results are in agreement with the theoretical prediction by G. Vemuri et al.[PRA,Vol.53(1996) p.2842].Comment: 12 pages, 5 figures, to appear on Applied Physics

Temperature Dependence Calibration and Correction of the DAMPE BGO Electromagnetic Calorimeter

A BGO electromagnetic calorimeter (ECAL) is built for the DArk Matter Particle Explorer (DAMPE) mission. The effect of temperature on the BGO ECAL was investigated with a thermal vacuum experiment. The light output of a BGO crystal depends on temperature significantly. The temperature coefficient of each BGO crystal bar has been calibrated, and a correction method is also presented in this paper

Ladder Horizontal Well Trajectory Control and Completion Technique in Ultra-Thin Reservoir

Daqing peripheral oilfield in the shallow layer is low abundance and low permeability thin interbed reservoir, which has the characteristics of multiple layers, low permeability, and small interlayer thickness. The reservoir development is not balanced. According to this characteristic, in order to be effective and economically develop this kind of reservoir, the research adopts stepped horizontal well development technology. And with the application of dynamics and kinematics theory, establishing a three-dimensional track ladder design of horizontal wells, horizontal section of casing string lifting limit and the mathematics model to calculate stress. The establishment of the analysis of drilling technology can accurately judge the position of bit and reservoir development, and timely adjust track.Key words: Thin layer; Stepped horizontal well; Optimization design; Trajectory control of; Cementing qualit

Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner.

The tumor promoter 12-O-tetra-decanoylphorbol-13-acetate (TPA) has been defined by its ability to promote tumorigenesis on carcinogen-initiated mouse skin. Activation of Wnt/β-catenin signaling has a decisive role in mouse skin carcinogenesis, but it remains unclear how TPA activates Wnt/β-catenin signaling in mouse skin carcinogenesis. Here, we found that TPA could enhance Wnt/β-catenin signaling in a casein kinase 1 (CK1) ε/δ-dependent manner. TPA stabilized CK1ε and enhanced its kinase activity. TPA further induced the phosphorylation of LRP6 at Thr1479 and Ser1490 and the formation of a CK1ε-LRP6-axin1 complex, leading to an increase in cytosolic β-catenin. Moreover, TPA increased the association of β-catenin with TCF4E in a CK1ε/δ-dependent way, resulting in the activation of Wnt target genes. Consistently, treatment with a selective CK1ε/δ inhibitor SR3029 suppressed TPA-induced skin tumor formation in vivo, probably through blocking Wnt/β-catenin signaling. Taken together, our study has identified a pathway by which TPA activates Wnt/β-catenin signaling

Changes of Carbon Emission in Chinese Regional Economy: A Decomposition Analysis Using Nested Logarithmic Mean Divisia Approach

This paper describes a nested logarithmic mean Divisia approach and analyzes the potential factors influencing the changes in carbon emission in Chinese northwest region for the period 1995-2010. The analysis is performed by decomposing annual carbon emission into components representing changes in economic activity, economic structure, energy mix, and energy intensity, population growth, population structure, as well as changes in per capita energy consumption and emission factor. This paper argues that the vast majority of changes in carbon emissions since 1995 are due to economic activity and energy intensity, where the former is found to be a predominant role in rising carbon emission and the later contributing dominantly to decreasing carbon emission. Moreover, the economic structure, population growth, and population structure effects are all found responsible for carbon emissions in the region, although their effects reverse in different time period. Besides, the decreases in carbon emission, however, are attributable mainly to per capita energy consumption and energy mix. There is no doubt that the current emission profile poses significant challenges to the local government’s policies for emission reduction. It is of vital importance to take into account the regional and stage characteristics of influences on carbon emission for policy making

Local multiscale model reduction using discontinuous Galerkin coupling for elasticity problems

In this paper, we consider the constrained energy minimizing generalized multiscale finite element method (CEM-GMsFEM) with discontinuous Galerkin (DG) coupling for the linear elasticity equations in highly heterogeneous and high contrast media. We will introduce the construction of a DG version of the CEM-GMsFEM, such as auxiliary basis functions and offline basis functions. The DG version of the method offers some advantages such as flexibility in coarse grid construction and sparsity of resulting discrete systems. Moreover, to our best knowledge, this is the first time where the proof of the convergence of the CEM-GMsFEM in the DG form is given. Some numerical examples will be presented to illustrate the performance of the method