Changes in Triglyceride Levels Over Time and Risk of Type 2 Diabetes in Young Men

OBJECTIVE—The association between changes in triglyceride concentrations over time and diabetes is unknown. We assessed whether two triglyceride determinations obtained 5 years apart can predict incident type 2 diabetes

Intrusion of Associative Distractors into Conceptual Performance by Acute Schizophrenics: Role of Associative Strength

37 acute schizophrenic patients were given a test measuring the extent to which associatively linked distractors intruded inappropriately into the formation of concepts. The test was administered both on admission to the hospital and after 6 wk. of phenothiazine or placebo treatment. Distractors were divided into four levels ranging from strong to weak associative linkages with relevant concept words. Stronger associative linkages in distractors were associated with more conceptual errors at both the pre- and post-treatment points ( p &lt; .001). These findings provide further support for the view that cognitive pathology in schizophrenia is characterized by pathological distractibility rather than loss in “abstract attitude.” </jats:p

Boundary Slope Control in Topology Optimization for Additive Manufacturing: For Self-Support and Surface Roughness

This paper studies how to control boundary slope of optimized parts in density-based topology optimization for additive manufacturing (AM). Boundary slope of a part affects the amount of support structure required during its fabrication by additive processes. Boundary slope also has a direct relation with the resulting surface roughness from the AM processes, which in turn affects the heat transfer efficiency. By constraining the minimal boundary slope, support structures can be eliminated or reduced for AM, and thus, material and postprocessing costs are reduced; by constraining the maximal boundary slope, high-surface roughness can be attained, and thus, the heat transfer efficiency is increased. In this paper, the boundary slope is controlled through a constraint between the density gradient and the given build direction. This allows us to explicitly control the boundary slope through density gradient in the density-based topology optimization approach. We control the boundary slope through two single global constraints. An adaptive scheme is also proposed to select the thresholds of these two boundary slope constraints. Numerical examples of linear elastic problem, heat conduction problem, and thermoelastic problems demonstrate the effectiveness and efficiency of the proposed formulation in controlling boundary slopes for additive manufacturing. Experimental results from metal 3D printed parts confirm that our boundary slope-based formulation is effective for controlling part self-support during printing and for affecting surface roughness of the printed parts.</jats:p