Functionalized Fly Ash Based Alumino-Silicates for Capture of Carbon Dioxide

Fly ash contains mainly alumina and silica as its main constituents. A novel method for the extraction of highly stable alumino-silicates from fly ash has been developed. The as-extracted alumino-silicate has been further functionalized with APTES ((3-aminopropyl)triethoxysilane), TRIS buffer (tris(hydroxymethyl)aminomethane), and AMP (3-amino-2-methyl-1-propanol) to impart basicity for carbon dioxide adsorption. A dynamic adsorption capacity of 6.62 mg/g has been observed for FAS (fly ash based alumino-silicate) and has improved by a factor of 4.0, with an adsorption capacity of 26.5 mg/g for AMP-functionalized FAS at 55 �C with 15% CO2 inN2. The positive influence of water was observed with an improvement of adsorption capacity to 34.82 mg/g at 55 �C with 15% CO2, 82% N2, and 3% water vapor. The adsorbent is studied for adsorption capacity at varying temperatures, and the best performing adsorbent is characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, thermal analysis, and elemental analysis to study the morphological properties of the present adsorbent support. The excellent thermal stability of synthesized material suggested the formation of promising aluminosilicate for CO2 adsorption

Molecular docking and molecular dynamic simulation of phytochemical derived compounds as potential anti cancer agent against tyrosine kinase

There is a continuous requirement to develop novel, safe, effective and affordable anti-cancer drugs because Cancer is a serious disease at current situation. A huge number of patients die annually due to cancer disease.  Phytochemical are the secondary metabolites of medicinal plants and significantly used in conventional cancer research.  Bioactive phytochemical is favored as they claim differentially on cancer cell only without altering normal cell. Carcinogenesis is an intricate process and includes multifold signaling procedures. Phytochemical are pleiotropic in nature, function and target these events in multiple manners so they are considered as most appropriate candidate for drug development. The aim of the present research was to find out the anti-cancer activity of the phytochemical constituents through computer aided drug design approach. In this experiment, we have find total 42 natural compounds with anti-cancer activity against the cancer target 1QCF tyrosine kinase. The data set comprising of phytochemical compounds was used for virtual screening and molecular docking in PyRx software. Along with screened compound, hit compound Carnosic acid was further docked to confirm the binding mode and confirmed the effective inhibition of 1QCF and anticancer activity. Molecular dynamic simulation studies were done to confirm the stability of the protein and ligand complex during a simulation. Parameters like RMSD, RMSF, and radius of gyration were experiential to understand the fluctuations. Protein-ligand interaction studies also expose that enough hydrogen and hydrophobic bonds are present to validate our results. Our study suggests that the potential use of Carnosic acid can come out as a potential candidate and in turn prevent cancer.</jats:p

Massive hemoptysis: A rare presentation of anterior mediastinal teratoma in an adolescent

Germ cell tumors are predominantly found in the gonads, and the most common extragonadal site is anterior mediastinum. Usual symptoms are cough, dyspnea, and fever, chest pain due to mass effect or intrapulmonary invasion but hemoptysis is rare and may result from either communication with tracheobronchial tree or may result from bronchial bleeding due to irritation by tumor. As in our case, patient presenting with massive hemoptysis and shock are the rarest presentation of a benign teratoma

Anodyne Practice of Turning Composite Fuel into Green Energy at Mini Thermal Power Plants in India

854-861The exploitation of non-renewable energy resources since last few decades has been a foremost concern for today’s generation. Most of the energy demand (about 63%) of India is outfitted by thermal power plants, leading to massive emission of CO2, thereafter, fly ash generation causing threat to eco-system. India being second largest producer of rice paddy globally also harvests large number of crops such as wheat, sugarcane, corn, etc. accreting substantial amount of biomass annually. In association with the current agenda for sustainable development, biomass (Rice Husk) co-firing with coal has been identified as most practicable solution for the energy generation in modern times particularly, for small scale power plants at rural sector. The paper explains comparative economy in power generation with the help of three cases based on theoretical assumptions. Composite fuel with biomass: coal ratio of 80:20 and 90:10 predicts about 8-10% economy in energy generation related with pure coal-based power plants. The leftover from this process is termed as composite ash, utilization of which is essential for environmental safety. Being diverse in composition than coal fly ash (CFA), composite ash can be turned into sodium silicate, powdered silica and further Molecular Sieves. All these products find commercial utility in chemical industries as an ion exchange, adsorbent, detergent-builder, abrasive, fertilizer, etc