199 research outputs found
Accurate and linear time pose estimation from points and lines
The final publication is available at link.springer.comThe Perspective-n-Point (PnP) problem seeks to estimate the pose of a calibrated camera from n 3Dto-2D point correspondences. There are situations, though, where PnP solutions are prone to fail because feature point correspondences cannot be reliably estimated (e.g. scenes with repetitive patterns or with low texture). In such
scenarios, one can still exploit alternative geometric entities, such as lines, yielding the so-called Perspective-n-Line (PnL) algorithms. Unfortunately, existing PnL solutions are not as accurate and efficient as their point-based
counterparts. In this paper we propose a novel approach to introduce 3D-to-2D line correspondences into a PnP formulation, allowing to simultaneously process points and lines. For this purpose we introduce an algebraic line error
that can be formulated as linear constraints on the line endpoints, even when these are not directly observable. These constraints can then be naturally integrated within the linear formulations of two state-of-the-art point-based algorithms,
the OPnP and the EPnP, allowing them to indistinctly handle points, lines, or a combination of them. Exhaustive experiments show that the proposed formulation brings remarkable boost in performance compared to only point or
only line based solutions, with a negligible computational overhead compared to the original OPnP and EPnP.Peer ReviewedPostprint (author's final draft
Inflation, cold dark matter, and the central density problem
A problem with high central densities in dark halos has arisen in the context
of LCDM cosmologies with scale-invariant initial power spectra. Although n=1 is
often justified by appealing to the inflation scenario, inflationary models
with mild deviations from scale-invariance are not uncommon and models with
significant running of the spectral index are plausible. Even mild deviations
from scale-invariance can be important because halo collapse times and
densities depend on the relative amount of small-scale power. We choose several
popular models of inflation and work out the ramifications for galaxy central
densities. For each model, we calculate its COBE-normalized power spectrum and
deduce the implied halo densities using a semi-analytic method calibrated
against N-body simulations. We compare our predictions to a sample of dark
matter-dominated galaxies using a non-parametric measure of the density. While
standard n=1, LCDM halos are overdense by a factor of 6, several of our example
inflation+CDM models predict halo densities well within the range preferred by
observations. We also show how the presence of massive (0.5 eV) neutrinos may
help to alleviate the central density problem even with n=1. We conclude that
galaxy central densities may not be as problematic for the CDM paradigm as is
sometimes assumed: rather than telling us something about the nature of the
dark matter, galaxy rotation curves may be telling us something about inflation
and/or neutrinos. An important test of this idea will be an eventual consensus
on the value of sigma_8, the rms overdensity on the scale 8 h^-1 Mpc. Our
successful models have values of sigma_8 approximately 0.75, which is within
the range of recent determinations. Finally, models with n>1 (or sigma_8 > 1)
are highly disfavored.Comment: 13 pages, 6 figures. Minor changes made to reflect referee's
Comments, error in Eq. (18) corrected, references updated and corrected,
conclusions unchanged. Version accepted for publication in Phys. Rev. D,
scheduled for 15 August 200
Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking. Here, we first discuss the generality of stress-induced reinstatement to different drugs of abuse, different stressors, and different behavioral procedures. We also discuss neuropharmacological mechanisms, and brain areas and circuits controlling stress-induced reinstatement of drug seeking. We conclude by discussing results from translational human laboratory studies and clinical trials that were inspired by results from rat studies on stress-induced reinstatement. Our main conclusions are (1) The phenomenon of stress-induced reinstatement, first shown with an intermittent footshock stressor in rats trained to self-administer heroin, generalizes to other abused drugs, including cocaine, methamphetamine, nicotine, and alcohol, and is also observed in the conditioned place preference model in rats and mice. This phenomenon, however, is stressor specific and not all stressors induce reinstatement of drug seeking. (2) Neuropharmacological studies indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dopamine, glutamate, kappa/dynorphin, and several other peptide and neurotransmitter systems in stress-induced reinstatement. Neuropharmacology and circuitry studies indicate the involvement of CRF and noradrenaline transmission in bed nucleus of stria terminalis and central amygdala, and dopamine, CRF, kappa/dynorphin, and glutamate transmission in other components of the mesocorticolimbic dopamine system (ventral tegmental area, medial prefrontal cortex, orbitofrontal cortex, and nucleus accumbens). (3) Translational human laboratory studies and a recent clinical trial study show the efficacy of alpha-2 adrenoceptor agonists in decreasing stress-induced drug craving and stress-induced initial heroin lapse
Nothing Lasts Forever: Environmental Discourses on the Collapse of Past Societies
The study of the collapse of past societies raises many questions for the theory and practice of archaeology. Interest in collapse extends as well into the natural sciences and environmental and sustainability policy. Despite a range of approaches to collapse, the predominant paradigm is environmental collapse, which I argue obscures recognition of the dynamic role of social processes that lie at the heart of human communities. These environmental discourses, together with confusion over terminology and the concepts of collapse, have created widespread aporia about collapse and resulted in the creation of mixed messages about complex historical and social processes
Linked Data Supported Content Analysis for Sociology
Philology and hermeneutics as the analysis and interpretation of natural language text in written historical sources are the predecessors of modern content analysis and date back already to antiquity. In empirical social sciences, especially in sociology, content analysis provides valuable insights to social structures and cultural norms of the present and past. With the ever growing amount of text on the web to analyze, also numerous computer-assisted text analysis techniques and tools were developed in sociological research. However, existing methods often go without sufficient standardization. As a consequence, sociological text analysis is lacking transparency, reproducibility and data re-usability.
The goal of this paper is to show, how Linked Data principles and Entity Linking techniques can be used to structure, publish and analyze natural language text for sociological research to tackle these shortcomings. This is achieved on the use case of constitutional text documents of the Netherlands from 1884 to 2016 which represent an important contribution to the European cultural heritage. Finally, the generated data is made available and re-usable as Linked Data not only for sociologists, but also for all other researchers in the digital humanities domain interested in the development of constitutions in the Netherlands
Ethical oversight in quality improvement and quality improvement research: new approaches to promote a learning health care system
The association of aggressive and chronic periodontitis with systemic manifestations and dental anomalies in a jordanian population: a case control study
<p>Abstract</p> <p><b>Background</b></p> <p>The relationship between dental anomalies and periodontitis has not been documented by earlier studies. Although psychological factors have been implicated in the etiopathogenesis of periodontitis, very little information has so far been published about the association of anxiety and depression with aggressive periodontitis. The aim of this study was to investigate the association of chronic periodontitis and aggressive periodontitis with certain systemic manifestations and dental anomalies.</p> <p><b>Methods</b></p> <p>A total of 262 patients (100 chronic periodontitis, 81 aggressive periodontitis and 81 controls), attending the Periodontology clinics at Jordan University of Science and Technology, Dental Teaching Centre) were included. All subjects had a full periodontal and radiographic examination to assess the periodontal condition and to check for the presence of any of the following dental anomalies: dens invaginatus, dens evaginatus, congenitally missing lateral incisors or peg-shaped lateral incisors. Participants were interrogated regarding the following: depressive mood, fatigue, weight loss, or loss of appetite; and their anxiety and depression status was assessed using the Hospital Anxiety and Depression (HAD) scale.</p> <p><b>Results</b></p> <p>Patients with aggressive periodontitis reported more systemic symptoms (51%) than the chronic periodontitis (36%) and control (30%) patients (<it>p </it>< 0.05). Aggressive periodontitis patients had a higher tendency for both anxiety and depression than chronic periodontitis and control patients. Dental anomalies were significantly (<it>p </it>< 0.05) more frequent among both of chronic and aggressive periodontitis patients (15% and 16%, respectively), compared to controls.</p> <p><b>Conclusion</b></p> <p>In this group of Jordanians, systemic symptoms were strongly associated with aggressive periodontitis, and dental anomalies were positively associated with both aggressive and chronic periodontitis.</p
Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients
Molecular Phylogeny and Evolution of Parabasalia with Improved Taxon Sampling and New Protein Markers of Actin and Elongation Factor-1α
BACKGROUND: Inferring the evolutionary history of phylogenetically isolated, deep-branching groups of taxa-in particular determining the root-is often extraordinarily difficult because their close relatives are unavailable as suitable outgroups. One of these taxonomic groups is the phylum Parabasalia, which comprises morphologically diverse species of flagellated protists of ecological, medical, and evolutionary significance. Indeed, previous molecular phylogenetic analyses of members of this phylum have yielded conflicting and possibly erroneous inferences. Furthermore, many species of Parabasalia are symbionts in the gut of termites and cockroaches or parasites and therefore formidably difficult to cultivate, rendering available data insufficient. Increasing the numbers of examined taxa and informative characters (e.g., genes) is likely to produce more reliable inferences. PRINCIPAL FINDINGS: Actin and elongation factor-1α genes were identified newly from 22 species of termite-gut symbionts through careful manipulations and seven cultured species, which covered major lineages of Parabasalia. Their protein sequences were concatenated and analyzed with sequences of previously and newly identified glyceraldehyde-3-phosphate dehydrogenase and the small-subunit rRNA gene. This concatenated dataset provided more robust phylogenetic relationships among major groups of Parabasalia and a more plausible new root position than those previously reported. CONCLUSIONS/SIGNIFICANCE: We conclude that increasing the number of sampled taxa as well as the addition of new sequences greatly improves the accuracy and robustness of the phylogenetic inference. A morphologically simple cell is likely the ancient form in Parabasalia as opposed to a cell with elaborate flagellar and cytoskeletal structures, which was defined as most basal in previous inferences. Nevertheless, the evolution of Parabasalia is complex owing to several independent multiplication and simplification events in these structures. Therefore, systematics based solely on morphology does not reflect the evolutionary history of parabasalids
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