21,119 research outputs found

    On the fate of vacuum bubbles on matter backgrounds

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    In this letter we discuss cosmological first order phase transitions with de Sitter bubbles nucleating on (inhomogeneous) matter backgrounds. The de Sitter bubble can be a toy model for an inflationary phase of universes like our own. Using the thin wall approximation and the Israel junction method we trace the classical evolution of the formed bubbles within a compound model. We first address homogeneous ambient space (FRW model) and already find that bubbles nucleated in a dust dominated background cannot expand. For an inhomogeneous dust background (LTB model) we describe cases with at least initially expanding bubbles. Yet, an ensuing passage of the bubble wall through ambient curvature inhomogeneities remains unnoticed for observers inside the bubble. Notable effects also for interior observers are found in the case of a rapid background phase transition in a FRW model.Comment: 4 pages, 2 figures, proceedings (Annalen der Physik) of the Grassmannian Conference in Fundamental Cosmology (Grasscosmofun'09) Szczecin, Poland, 14-19 September 200

    What Will You Do If I Say 'I Do'?: The Effect of the Sex Ratio on Time Use within Taiwanese Married Couples

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    This paper uses the natural experiment of a large imbalance between men and women of marriageable age in Taiwan in the 1960s to test the hypothesis that higher sex ratios lead to husbands (wives) having a lower (higher) share of couple's time in leisure and higher (lower) share of the couple's total work time (employment, commuting and housework). A large sample of Taiwanese couples' time diaries from 1987, 1990, and 1994 is used. The analysis finds evidence of the predicted effects of the county-level sex ratio on husbands' and wives' share of leisure and total work time. In addition, the age difference between husbands and wives is shown to be positively correlated with heightened county-level sex ratio a result which is also consistent with the theory that marriage market participants' choices are affected by the prevailing sex ratio

    Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys.

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    These studies focused on a new radiolabeling technique with copper ((64)Cu) and zirconium ((89)Zr) for positron emission tomography (PET) imaging using a CD45 antibody. Synthesis of (64)Cu-CD45 and (89)Zr-CD45 immunoconjugates was performed and the evaluation of the potential toxicity of radiolabeling human peripheral blood stem cells (hPBSC) was assessed in vitro (viability, population doubling times, colony forming units). hPBSC viability was maintained as the dose of (64)Cu-TETA-CD45 increased from 0 (92%) to 160 µCi/mL (76%, p>0.05). Radiolabeling efficiency was not significantly increased with concentrations of (64)Cu-TETA-CD45 >20 µCi/mL (p>0.50). Toxicity affecting both growth and colony formation was observed with hPBSC radiolabeled with ≥40 µCi/mL (p<0.05). For (89)Zr, there were no significant differences in viability (p>0.05), and a trend towards increased radiolabeling efficiency was noted as the dose of (89)Zr-Df-CD45 increased, with a greater level of radiolabeling with 160 µCi/mL compared to 0-40 µCi/mL (p<0.05). A greater than 2,000 fold-increase in the level of (89)Zr-Df-CD45 labeling efficiency was observed when compared to (64)Cu-TETA-CD45. Similar to (64)Cu-TETA-CD45, toxicity was noted when hPBSC were radiolabeled with ≥40 µCi/mL (p<0.05) (growth, colony formation). Taken together, 20 µCi/mL resulted in the highest level of radiolabeling efficiency without altering cell function. Young rhesus monkeys that had been transplanted prenatally with 25×10(6) hPBSC expressing firefly luciferase were assessed with bioluminescence imaging (BLI), then 0.3 mCi of (89)Zr-Df-CD45, which showed the best radiolabeling efficiency, was injected intravenously for PET imaging. Results suggest that (89)Zr-Df-CD45 was able to identify engrafted hPBSC in the same locations identified by BLI, although the background was high
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