169 research outputs found
Концепт любов в іспаномовній Біблії: лінгвокультурологічний аспект (The concept love in the Spanish Bible: linguocultural aspect)
Стаття пов’язана з проблемою текстового втілення концепту ЛЮБОВ в іспаномовній Біблії. Сформульовано теоретичні засади дослідження концепту ЛЮБОВ у біблійному тексті. Розроблено методику дослідження концепту ЛЮБОВ. Окреслено вербальну репрезентацію концепту ЛЮБОВ у картині світу носіїв іспанської мови. Визначено етнокультурну специфіку засобів репрезентації концепту ЛЮБОВ в іспаномовному тексті Біблії.
(The article is connected with the problem of textual embodiment of the concept LOVE in the Spanish Bible. Is defined theoretical background of the concepts study in the Bible text. A complex methodology for the analysis of the concept Love has been elaborated. The verbal representation of the concept is revealed in the world view of native speakers of Spanish. The ethnic and cultural specificity of representation means of the concept Love in the Spanish Bible has been determined.
ФУНКЦІОНАЛЬНІ ОСОБЛИВОСТІ ОБРАЗНОЇ СИСТЕМИ ІСПАНСЬКОЇ КАЗКИ (Functional peculiarities of the figurative system of Spanish tale)
У статті розкриваються закономірності образної системи іспанської казки як комунікативно-прагматичного репрезентанта іспанської ментальності.
(The article deals with the investigation of figurative system of Spanish tale as a communicative and pragmatic
representation of Spanish mentality.
A Survey of Requirements for COVID-19 Mitigation Strategies. Part I: Newspaper Clips
The COVID-19 pandemic has influenced virtually all aspects of our lives.
Across the world, countries have applied various mitigation strategies for the
epidemic, based on social, political, and technological instruments. We
postulate that one should {identify the relevant requirements} before
committing to a particular mitigation strategy. One way to achieve it is
through an overview of what is considered relevant by the general public, and
referred to in the media. To this end, we have collected a number of news clips
that mention the possible goals and requirements for a mitigation strategy. The
snippets are sorted thematically into several categories, such as
health-related goals, social and political impact, civil rights, ethical
requirements, and so on.
In a forthcoming companion paper, we will present a digest of the
requirements, derived from the news clips, and a preliminary take on their
formal specification
The Vascular Impairment of Cognition Classification Consensus Study
Introduction: Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment. / Methods: The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines. / Results: VICCCS had a mean of 122 (98–153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge. / Discussion: VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research
Fungal Populations in Air and Materials in a Flood Simulation Study
Air quality was measured in a building subjected to flooding conditions analogous to that which occurred during Hurricane Katrina. This building was flooded to a depth of 0.61 m above the floor with pond water and maintained at that level for 3 wk. After the floodwater was drained, the building remained closed for an additional 3 wk. Immediately on opening, air samples were obtained and analyzed for fungal spores. Dry and wet material components of the building wall were analyzed for the presence of mold fungi by both culture and molecular techniques. Additional air samples were taken after a 30-da drying period and then after remediation of the building. The air measurements demonstrated the presence of high concentrations of indoor mold spores when the building was initially entered. Aspergillus/Penicillium were the dominate air molds. Fiberglass batt insulation supported the greatest concentration of culturable fungi, compared with other wall materials, followed by the paper facings of gypsum board and plywood sheathing. The solid wood stud, vinyl siding, and house wrap all supported low concentrations of culturable mold. After drying, the spore air contamination diminished more than 10-fold and the species of fungi on the materials drastically changed. After remediation, the spores inside the structure nearly matched those outside with respect to type and concentration
Post-mortem assessment in vascular dementia: advances and aspirations.
BACKGROUND: Cerebrovascular lesions are a frequent finding in the elderly population. However, the impact of these lesions on cognitive performance, the prevalence of vascular dementia, and the pathophysiology behind characteristic in vivo imaging findings are subject to controversy. Moreover, there are no standardised criteria for the neuropathological assessment of cerebrovascular disease or its related lesions in human post-mortem brains, and conventional histological techniques may indeed be insufficient to fully reflect the consequences of cerebrovascular disease. DISCUSSION: Here, we review and discuss both the neuropathological and in vivo imaging characteristics of cerebrovascular disease, prevalence rates of vascular dementia, and clinico-pathological correlations. We also discuss the frequent comorbidity of cerebrovascular pathology and Alzheimer's disease pathology, as well as the difficult and controversial issue of clinically differentiating between Alzheimer's disease, vascular dementia and mixed Alzheimer's disease/vascular dementia. Finally, we consider additional novel approaches to complement and enhance current post-mortem assessment of cerebral human tissue. CONCLUSION: Elucidation of the pathophysiology of cerebrovascular disease, clarification of characteristic findings of in vivo imaging and knowledge about the impact of combined pathologies are needed to improve the diagnostic accuracy of clinical diagnoses
SweetPAKE: Key exchange with decoy passwords
peer reviewedDecoy accounts are often used as an indicator of the compromise of sensitive data, such as password files. An attacker targeting only specific known-to-be-real accounts might, however, remain undetected. A more effective method proposed by Juels and Rivest at CCS’13 is to maintain additional fake passwords associated with each account. An attacker who gains access to the password file is unable to tell apart real passwords from fake passwords, and the attempted usage of a false password immediately sets off an alarm indicating a password file compromise. Password-Authenticated Key Exchange (PAKE) has long been recognised for its strong security guarantees when it comes to low-entropy password authentication and secure channel establishment, without having to rely on the setup of a PKI. In this paper, we introduce SweetPAKE, a new cryptographic primitive that offers the same security guarantees as PAKE for key exchange, while allowing clients with a single password to authenticate against servers with n candidate passwords for that account and establish a secure channel. Additional security properties are identified and formalized to ensure that (a) high-entropy session keys are indistinguishable from random, even if later on the long-term secret password becomes corrupted (forward secrecy); (b) upon password file leakage, an adversary cannot tell apart real from fake passwords; and (c) a malicious client cannot trigger a false alarm. We capture these properties by extending well-established game-based definitions of PAKE. Furthermore, we propose a new UC formulation that comprehensively unifies both SweetPAKE (session key indistinguishability and sugarword indistinguishability) and a related notion known as Oblivious-PAKE. Finally, we propose efficient SweetPAKE and Oblivious-PAKE protocols constructed from Password-Authenticated Public-Key Encryption (PAPKE) that satisfy all the proposed notions
Improving the diagnostic accuracy of referrals for papilloedema (DIPP) study: protocol for a mixed-methods study.
INTRODUCTION: Papilloedema can be the first sign of life-threatening disease, for example, brain tumours. Due to the potential seriousness of this clinical sign, the detection of papilloedema would normally prompt urgent hospital referral for further investigation. The problem is that many benign structural variations of optic nerve anatomy can be mistaken for papilloedema, so-called pseudopapilloedema. The consequence is that many people are referred to hospital because they are incorrectly identified to have papilloedema when they don't. As a result, hospital referrals of people with suspected papilloedema in England have increased sharply, leading to increased demand for overstretched hospital services and potentially longer waiting times for hospital appointments for those who do have papilloedema.The work programme is aimed at the development of guidelines and educational materials that will help support health professionals to correctly identify people with papilloedema. This article describes the protocol for gathering evidence of current referral practices and pathways for people suspected to have papilloedema in England and the development of guidelines based on this evidence and extensive engagement with community- and hospital-based healthcare professionals, patients, and the public. METHODS AND ANALYSIS: Both qualitative and quantitative data will be collected from Freedom of Information requests to Integrated Care Boards across England about how they organise their community and hospital services for people with suspected papilloedema, with and without headache. Surveys and qualitative interviews of relevant community and hospital healthcare professionals based in England will collect data on how and when people with papilloedema and pseudopapilloedema with or without headache are currently identified and referred to hospital, if needed. This information will be used to inform a Delphi process with the aim of reaching consensus among health professional experts, commissioners and patients on what the most evidence-based and safe diagnostic and referral practices should be for people with suspected papilloedema. The tailored guidelines will be written for healthcare professionals and patients. We will create a range of educational materials and a website designed for health professionals and patients to support the national roll-out and implementation of DIPP study guidelines. ETHICS AND DISSEMINATION: Ethical approval was granted by the University of Bristol Faculty of Health Sciences Ethics committee (FREC reference: 12457) and Health Research Authority (IRAS no.: 320395). Results of the study will be published on our DIPP study website and disseminated to our stakeholder groups through peer-reviewed journal publications and conference presentations
VII. Discours
Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65–79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders–Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders–Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration
Verifying Artifact Authenticity with Unclonable Optical Tags
peer reviewedWe study the challenge of authenticating objects. This problem is relevant when buyers need proof that a purchase is authentic and not fake. Typically, manufacturers watermark their goods, give them IDs, and provide a certificate of authenticity. Buyers, for their part, check the IDs and verify the certificate. However, even if manufacturers are honest online registration and verification are vulnerable to hacking; servers can leak private data; goods out-for-delivery can have the ID cloned and can be replaced with imitations. We propose a cyber-physical solution that combines physical properties and cryptographic protocols and that is robust against a curious registry server and attempts to physical manipulation. Security depends on two elements: (I) a material inseparably joined with an object from which we can generate digital identities and other cryptographic tokens; (ii) two novel cryptographic protocols that ensure data and object integrity and authentication of agents and objects. Besides, we show that a material with all the desired security properties exists. We can use it to coat objects, and it has optical properties, such as unclonability, from which we can build secure cryptographic protocols. We formally prove our security claims with Proverif
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