Bulk singularities at critical end points: a field-theory analysis

A class of continuum models with a critical end point is considered whose Hamiltonian ${\mathcal{H}}[\phi,\psi]$ involves two densities: a primary order-parameter field, $\phi$, and a secondary (noncritical) one, $\psi$. Field-theoretic methods (renormalization group results in conjunction with functional methods) are used to give a systematic derivation of singularities occurring at critical end points. Specifically, the thermal singularity $\sim|{t}|^{2-\alpha}$ of the first-order line on which the disordered or ordered phase coexists with the noncritical spectator phase, and the coexistence singularity $\sim |{t}|^{1-\alpha}$ or $\sim|{t}|^{\beta}$ of the secondary density $$ are derived. It is clarified how the renormalization group (RG) scenario found in position-space RG calculations, in which the critical end point and the critical line are mapped onto two separate fixed points ${\mathcal P}_{\mathrm{CEP}}^*$ and ${\mathcal P}_{\lambda}^*$ translates into field theory. The critical RG eigenexponents of ${\mathcal P}_{\mathrm{CEP}}^*$ and ${\mathcal P}_{\lambda}^*$ are shown to match. ${\mathcal P}_{\mathrm{CEP}}^*$ is demonstrated to have a discontinuity eigenperturbation (with eigenvalue $y=d$), tangent to the unstable trajectory that emanates from ${\mathcal P}_{\mathrm{CEP}}^*$ and leads to ${\mathcal P}_{\lambda}^*$. The nature and origin of this eigenperturbation as well as the role redundant operators play are elucidated. The results validate that the critical behavior at the end point is the same as on the critical line.Comment: Latex file; uses epj stylefiles svepj.clo and svjour.cls. Two eps files as figures included; uses texdraw to generate some figures Only some remarks added in last Section of this final versio

Field-Theoretical Analysis of Critical and Coexistence Singularities at Critical End Points

Continuum models with critical end points are considered whose Hamiltonian ${\mathcal{H}}[\phi,\psi]$ depends on two densities $\phi$ and $\psi$. Field-theoretic methods are used to show the equivalence of the critical behavior on the critical line and at the critical end point and to give a systematic derivation of critical-end-point singularities like the thermal singularity $\sim|{t}|^{2-\alpha}$ of the spectator-phase boundary and the coexistence singularities $\sim |{t}|^{1-\alpha}$ or $\sim|{t}|^{\beta}$ of the secondary density $$. The appearance of a discontinuity eigenexponent associated with the critical end point is confirmed, and the mechanism by which it arises in field theory is clarified.Comment: Latex2e file using elsart stylefile, no figures. submitted to Proceedings of Statphys Taipei-99, to be published in Physica

Development of targeted messages to promote smoking cessation among construction trade workers

Blue-collar workers, particularly those in the construction trades, are more likely to smoke and have less success in quitting when compared with white-collar workers. Little is known about health communication strategies that might influence this priority population. This article describes our formative work to develop targeted messages to increase participation in an existing smoking cessation program among construction workers. Using an iterative and sequential mixed-methods approach, we explored the culture, health attitudes and smoking behaviors of unionized construction workers. We used focus group and survey data to inform message development, and applied audience segmentation methods to identify potential subgroups. Among 144 current smokers, 65% reported wanting to quit smoking in the next 6 months and only 15% had heard of a union-sponsored smoking cessation program, despite widespread advertising. We tested 12 message concepts and 26 images with the target audience to evaluate perceived relevance and effectiveness. Participants responded most favorably to messages and images that emphasized family and work, although responses varied by audience segments based on age and parental status. This study is an important step towards integrating the culture of a high-risk group into targeted messages to increase participation in smoking cessation activities

Critical Casimir effect in classical binary liquid mixtures

If a fluctuating medium is confined, the ensuing perturbation of its fluctuation spectrum generates Casimir-like effective forces acting on its confining surfaces. Near a continuous phase transition of such a medium the corresponding order parameter fluctuations occur on all length scales and therefore close to the critical point this effect acquires a universal character, i.e., to a large extent it is independent of the microscopic details of the actual system. Accordingly it can be calculated theoretically by studying suitable representative model systems. We report on the direct measurement of critical Casimir forces by total internal reflection microscopy (TIRM), with femto-Newton resolution. The corresponding potentials are determined for individual colloidal particles floating above a substrate under the action of the critical thermal noise in the solvent medium, constituted by a binary liquid mixture of water and 2,6-lutidine near its lower consolute point. Depending on the relative adsorption preferences of the colloid and substrate surfaces with respect to the two components of the binary liquid mixture, we observe that, upon approaching the critical point of the solvent, attractive or repulsive forces emerge and supersede those prevailing away from it. Based on the knowledge of the critical Casimir forces acting in film geometries within the Ising universality class and with equal or opposing boundary conditions, we provide the corresponding theoretical predictions for the sphere-planar wall geometry of the experiment. The experimental data for the effective potential can be interpreted consistently in terms of these predictions and a remarkable quantitative agreement is observed.Comment: 30 pages, 17 figure

Peacebuilding for faith-based development organisations: Informing theory and practice

Abstract Faith leaders and their congregations have been recognised as holding the potential to engage positively in peacebuilding activities in a post-conflict context. Alongside this, faith-based development organisations (FBDOs) have the ability to engage with these constituencies to increase the peacebuilding impact of their activities. This paper presents a framework of faith engagement for FBDOs to work with local faith leaders and people of faith to develop the peacebuilding impact of development activities. A reworking of Anderson's "Do No Harm", it encompasses the areas that FBDOs need to address in order to be effective peacebuilding actors in a faith context

Critical Casimir forces and adsorption profiles in the presence of a chemically structured substrate

Motivated by recent experiments with confined binary liquid mixtures near demixing, we study the universal critical properties of a system, which belongs to the Ising universality class, in the film geometry. We employ periodic boundary conditions in the two lateral directions and fixed boundary conditions on the two confining surfaces, such that one of them has a spatially homogeneous adsorption preference while the other one exhibits a laterally alternating adsorption preference, resembling locally a single chemical step. By means of Monte Carlo simulations of an improved Hamiltonian, so that the leading scaling corrections are suppressed, numerical integration, and finite-size scaling analysis we determine the critical Casimir force and its universal scaling function for various values of the aspect ratio of the film. In the limit of a vanishing aspect ratio the critical Casimir force of this system reduces to the mean value of the critical Casimir force for laterally homogeneous ++ and +- boundary conditions, corresponding to the surface spins on the two surfaces being fixed to equal and opposite values, respectively. We show that the universal scaling function of the critical Casimir force for small but finite aspect ratios displays a linear dependence on the aspect ratio which is solely due to the presence of the lateral inhomogeneity. We also analyze the order-parameter profiles at criticality and their universal scaling function which allows us to probe theoretical predictions and to compare with experimental data.Comment: revised version, section 5.2 expanded; 53 pages, 12 figures, iopart clas

Fertility, Living Arrangements, Care and Mobility

There are four main interconnecting themes around which the contributions in this book are based. This introductory chapter aims to establish the broad context for the chapters that follow by discussing each of the themes. It does so by setting these themes within the overarching demographic challenge of the twenty-first century – demographic ageing. Each chapter is introduced in the context of the specific theme to which it primarily relates and there is a summary of the data sets used by the contributors to illustrate the wide range of cross-sectional and longitudinal data analysed

Functional Diversity and Structural Disorder in the Human Ubiquitination Pathway

The ubiquitin-proteasome system plays a central role in cellular regulation and protein quality control (PQC). The system is built as a pyramid of increasing complexity, with two E1 (ubiquitin activating), few dozen E2 (ubiquitin conjugating) and several hundred E3 (ubiquitin ligase) enzymes. By collecting and analyzing E3 sequences from the KEGG BRITE database and literature, we assembled a coherent dataset of 563 human E3s and analyzed their various physical features. We found an increase in structural disorder of the system with multiple disorder predictors (IUPred - E1: 5.97%, E2: 17.74%, E3: 20.03%). E3s that can bind E2 and substrate simultaneously (single subunit E3, ssE3) have significantly higher disorder (22.98%) than E3s in which E2 binding (multi RING-finger, mRF, 0.62%), scaffolding (6.01%) and substrate binding (adaptor/substrate recognition subunits, 17.33%) functions are separated. In ssE3s, the disorder was localized in the substrate/adaptor binding domains, whereas the E2-binding RING/HECT-domains were structured. To demonstrate the involvement of disorder in E3 function, we applied normal modes and molecular dynamics analyses to show how a disordered and highly flexible linker in human CBL (an E3 that acts as a regulator of several tyrosine kinase-mediated signalling pathways) facilitates long-range conformational changes bringing substrate and E2-binding domains towards each other and thus assisting in ubiquitin transfer. E3s with multiple interaction partners (as evidenced by data in STRING) also possess elevated levels of disorder (hubs, 22.90% vs. non-hubs, 18.36%). Furthermore, a search in PDB uncovered 21 distinct human E3 interactions, in 7 of which the disordered region of E3s undergoes induced folding (or mutual induced folding) in the presence of the partner. In conclusion, our data highlights the primary role of structural disorder in the functions of E3 ligases that manifests itself in the substrate/adaptor binding functions as well as the mechanism of ubiquitin transfer by long-range conformational transitions. © 2013 Bhowmick et al