105 research outputs found
Impact of right-handed interactions on the propagation of Dirac and Majorana neutrinos in matter
Dirac and Majorana neutrinos can be distinguished in relativistic neutrino
oscillations if new right-handed interactions exist, due to their different
propagation in matter. We review how these new interactions affect neutrino
oscillation experiments and discuss the size of this eventually observable
effect for different oscillation channels, baselines and neutrino energies.Comment: 26 pages, 5 figure
Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence
Large repeat rich genomes present challenges for assembly using short read technologies. The 32 Gb axolotl genome is estimated to contain ~19 Gb of repetitive DNA making an assembly from short reads alone effectively impossible. Indeed, this model species has been sequenced to 20× coverage but the reads could not be conventionally assembled. Using an alternative strategy, we have assembled subsets of these reads into scaffolds describing over 19,000 gene models. We call this method Virtual Genome Walking as it locally assembles whole genome reads based on a reference transcriptome, identifying exons and iteratively extending them into surrounding genomic sequence. These assemblies are then linked and refined to generate gene models including upstream and downstream genomic, and intronic, sequence. Our assemblies are validated by comparison with previously published axolotl bacterial artificial chromosome (BAC) sequences. Our analyses of axolotl intron length, intron-exon structure, repeat content and synteny provide novel insights into the genic structure of this model species. This resource will enable new experimental approaches in axolotl, such as ChIP-Seq and CRISPR and aid in future whole genome sequencing efforts. The assembled sequences and annotations presented here are freely available for download from https://tinyurl.com/y8gydc6n. The software pipeline is available from https://github.com/LooseLab/iterassemble
Many Labs 2: Investigating Variation in Replicability Across Samples and Settings
We conducted preregistered replications of 28 classic and contemporary published findings, with protocols that were peer reviewed in advance, to examine variation in effect magnitudes across samples and settings. Each protocol was administered to approximately half of 125 samples that comprised 15,305 participants from 36 countries and territories. Using the conventional criterion of statistical significance (p < .05), we found that 15 (54%) of the replications provided evidence of a statistically significant effect in the same direction as the original finding. With a strict significance criterion (p < .0001), 14 (50%) of the replications still provided such evidence, a reflection of the extremely highpowered design. Seven (25%) of the replications yielded effect sizes larger than the original ones, and 21 (75%) yielded effect sizes smaller than the original ones. The median comparable Cohen’s ds were 0.60 for the original findings and 0.15 for the replications. The effect sizes were small (< 0.20) in 16 of the replications (57%), and 9 effects (32%) were in the direction opposite the direction of the original effect. Across settings, the Q statistic indicated significant heterogeneity in 11 (39%) of the replication effects, and most of those were among the findings with the largest overall effect sizes; only 1 effect that was near zero in the aggregate showed significant heterogeneity according to this measure. Only 1 effect had a tau value greater than .20, an indication of moderate heterogeneity. Eight others had tau values near or slightly above .10, an indication of slight heterogeneity. Moderation tests indicated that very little heterogeneity was attributable to the order in which the tasks were performed or whether the tasks were administered in lab versus online. Exploratory comparisons revealed little heterogeneity between Western, educated, industrialized, rich, and democratic (WEIRD) cultures and less WEIRD cultures (i.e., cultures with relatively high and low WEIRDness scores, respectively). Cumulatively, variability in the observed effect sizes was attributable more to the effect being studied than to the sample or setting in which it was studied.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Instituto de Investigaciones Psicológicas (IIP
Chosen determinants of consumers behaviours of dairy products
Zidentyfikowano determinanty konsumpcji produktów mleczarskich oraz wyniki badania ankietowego
potencjalnych konsumentów tych produktów. Ogólna dostępność dóbr żywnościowych na rynku,
konkurencyjne ceny i atrakcyjność oferty podażowej, a także zmieniające się upodobania i preferencje
konsumentów spowodowały istotne zmiany w zachowaniach konsumpcyjnych gospodarstw domowych.
Sprzyjało to przede wszystkim substytucji pomiędzy produktami i w obrębie grup produktów, a także poszukiwaniu
produktów wygodnych w użyciu.The determinants of dairy products consumption as well as the questionnaire survey results on potential
consumers of those products have been presented. The general accessibility of nutritive goods on the market,
their competitive prices and the attractiveness of the supply offer as well as the changing tastes and preferences
of consumers have brought about significant changes in the behaviours of consumer households. Most of
all, substitutions among products and within groups of products as well as search for products convenient
in use were favoured by the consumers, along with the priority treatment of fresh food and increase of trust
in ecological food
Legal Professionals and Multicultural Competence: the Impact of Acculturation, Ethnic Identity, and Racial Attitudes
We may not know much about the deep sea, but do we care about mining it?
1. The way we value the environment affects how we treat it. While public awareness of human impacts on the ocean is increasing, industrial activities in the deep sea are accelerating rapidly and out of sight. 2. The underlying values we hold for the environment were increasingly recognised as an important factor in environmental decision-making, and it was thus important to evaluate public values towards deep-sea environments. 3. Here, we explored people's care for the deep sea and related this to the perceived risks of seafloor mining by comparing the deep sea to three other remote environments: Antarctica, remote terrestrial environments and the Moon. 4. We conducted an online survey to investigate symbolic values, which we define as the emotions, moods and meanings an environment evokes, as an element affecting people's care for the environment. In addition, we investigated the respondent's knowledge, worldviews and the perceived environmental and societal risk of mining in these four environments. 5. We found that symbolic values shape people's environmental care and that the overall symbolic value attributed to each of the environments differs. 6. People perceived it likely that mining will take place in the deep sea, and the majority of respondents (81%) stated to care a lot or very much about human activities harming the deep sea. 7. In comparison to the other remote environments, in a general sense people cared less about the deep sea, and their self-assessed knowledge of the deep sea was lower. 8. These results suggest that it was fundamental to account for the underlying values and emotions towards the environment when evaluating the risks of human activities in remote settings. 9. Our results further highlighted the need to improve public understanding and connection with the deep sea and its role within wider society to engender deep-sea stewardship.Peer reviewe
Structural and functional analysis of intra-articular interzone tissue in axolotl salamanders
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