1,816 research outputs found
Nonconfocal multimode resonators for masers
The case of a resonator composed of two concave spherical reflectors separated by an arbitrary distance is examined. The general problem of the electromagnetic field distribution over the nonconfocal aperture is first formulated by means of the Huygens principle. The solution of the resulting integral equation is obtained analytically in the highly nonconfocal limit. It was found that when the reflector spacing d is much larger than the radius of curvature b of the reflectors, the aperture field distribution is in the form of traveling waves. For arbitrary d/b, the eigenvalues and eigenfunctions of the lowest order mode is obtained by numerical solution using the IBM 7090 computer. The diffraction loss was found to increase rapidly when d→2b and a geometrical interpretation of this behavior is given. Furthermore, it was found that as the spacing departs from the confocal value, the apertures are no longer surfaces of constant phase. The optimum spacing for maximum Q of the resonator is also obtained
High power phase locked laser oscillators
The feasibility of mechanizing an adaptive array of independent laser oscillators for generation of a high power coherent output was experimentally investigated. Tests were structured to evaluate component/system requirements for delivery of energy to a low-earth orbit satellite. Initial experiments addressed the control issues of phase locking unstable resonators at low power levels. A successful phase lock demonstration formed the basis for the design and fabrication of the high power, water-cooled, control mirror subsequently installed in the NASA LeRC high power laser. Tests were performed to characterize the operational limits of the laser system and included quantitative assessment of the frequency stability, noise sources, and optical properties of the beam
Aerodynamic interference effects on tilting proprotor aircraft
The Green's function method was used to study tilting proprotor aircraft aerodynamics with particular application to the problem of the mutual interference of the wing-fuselage-tail-rotor wake configuration. While the formulation is valid for fully unsteady rotor aerodynamics, attention was directed to steady state aerodynamics, which was achieved by replacing the rotor with the actuator disk approximation. The use of an actuator disk analysis introduced a mathematical singularity into the formulation; this problem was studied and resolved. The pressure distribution, lift, and pitching moment were obtained for an XV-15 wing-fuselage-tail rotor configuration at various flight conditions. For the flight configurations explored, the effects of the rotor wake interference on the XV-15 tilt rotor aircraft yielded a reduction in the total lift and an increase in the nose-down pitching moment. This method provides an analytical capability that is simple to apply and can be used to investigate fuselage-tail rotor wake interference as well as to explore other rotor design problem areas
Quantized spin excitations in a ferromagnetic microstrip from microwave photovoltage measurements
Quantized spin excitations in a single ferromagnetic microstrip have been
measured using the microwave photovoltage technique. Several kinds of spin wave
modes due to different contributions of the dipole-dipole and the exchange
interactions are observed. Among them are a series of distinct dipole-exchange
spin wave modes, which allow us to determine precisely the subtle spin boundary
condition. A comprehensive picture for quantized spin excitations in a
ferromagnet with finite size is thereby established. The dispersions of the
quantized spin wave modes have two different branches separated by the
saturation magnetization.Comment: 4 pages, 3 figure
Controlling chaos in spatially extended beam-plasma system by the continuous delayed feedback
In present paper we discuss the control of complex spatio-temporal dynamics
in a {spatially extended} non-linear system (fluid model of Pierce diode) based
on the concepts of controlling chaos in the systems with few degrees of
freedom. A presented method is connected with stabilization of unstable
homogeneous equilibrium state and the unstable spatio-temporal periodical
states analogous to unstable periodic orbits of chaotic dynamics of the systems
with few degrees of freedom. We show that this method is effective and allows
to achieve desired regular dynamics chosen from a number of possible in the
considered system.Comment: 12 pages, 12 figure
Chaotic synchronization of coupled electron-wave systems with backward waves
The chaotic synchronization of two electron-wave media with interacting
backward waves and cubic phase nonlinearity is investigated in the paper. To
detect the chaotic synchronization regime we use a new approach, the so-called
time scale synchronization [Chaos, 14 (3) 603-610 (2004)]. This approach is
based on the consideration of the infinite set of chaotic signals' phases
introduced by means of continuous wavelet transform. The complex space-time
dynamics of the active media and mechanisms of the time scale synchronization
appearance are considered.Comment: 11 pages, 7 figures, published in CHAOS, 15 (2005) 01370
Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.
Protease-activated receptor 1 (PAR1) is a G protein-coupled receptor (GPCR) for thrombin and promotes inflammatory responses through multiple pathways including p38 mitogen-activated protein kinase signaling. The mechanisms that govern PAR1-induced p38 activation remain unclear. Here, we define an atypical ubiquitin-dependent pathway for p38 activation used by PAR1 that regulates endothelial barrier permeability. Activated PAR1 K63-linked ubiquitination is mediated by the NEDD4-2 E3 ubiquitin ligase and initiated recruitment of transforming growth factor-β-activated protein kinase-1 binding protein-2 (TAB2). The ubiquitin-binding domain of TAB2 was essential for recruitment to PAR1-containing endosomes. TAB2 associated with TAB1, which induced p38 activation independent of MKK3 and MKK6. The P2Y1 purinergic GPCR also stimulated p38 activation via NEDD4-2-mediated ubiquitination and TAB1-TAB2. TAB1-TAB2-dependent p38 activation was critical for PAR1-promoted endothelial barrier permeability in vitro, and p38 signaling was required for PAR1-induced vascular leakage in vivo. These studies define an atypical ubiquitin-mediated signaling pathway used by a subset of GPCRs that regulates endosomal p38 signaling and endothelial barrier disruption
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Racial and Ethnic Differences in Mortality Associated with Serum Potassium in Incident Peritoneal Dialysis Patients.
BackgroundAbnormalities in serum potassium are risk factors for sudden cardiac death and arrhythmias among dialysis patients. Although a previous study in hemodialysis patients has shown that race/ethnicity may impact the relationship between serum potassium and mortality, the relationship remains unclear among peritoneal dialysis (PD) patients where the dynamics of serum potassium is more stable.MethodsAmong 17,664 patients who started PD between January 1, 2007 and December 31, 2011 in a large US dialysis organization, we evaluated the association of serum potassium levels with all-cause and arrhythmia-related deaths across race/ethnicity using time-dependent Cox models with adjustments for demographics. We also used restricted cubic spline functions for serum potassium levels to explore non-linear associations.ResultsBaseline serum potassium levels were the highest among Hispanics (4.2 ± 0.7 mEq/L) and lowest among non-Hispanic blacks (4.0 ± 0.7 mEq/L). Among 2,949 deaths during the follow-up of median 2.2 (interquartile ranges 1.3-3.2) years, 683 (23%) were arrhythmia-related deaths. Overall, both hyperkalemia and hypokalemia (i.e., serum potassium levels >5.0 and <3.5 mEq/L, respectively) were associated with higher all-cause and arrhythmia-related mortality. In a stratified analysis according to race/ethnicity, the association of hypokalemia with all-cause and arrhythmia-related mortality was consistent with an attenuation for arrhythmia-related mortality in non-Hispanic blacks. Hyperkalemia was associated with all-cause and arrhythmia-related mortality in non-Hispanic whites and non-Hispanic blacks, but no association was observed in Hispanics.ConclusionAmong incident PD patients, hypokalemia was consistently associated with all-cause and arrhythmia-related deaths irrespective of race/ethnicity. However, while hyperkalemia was associated with both death outcomes in non-Hispanic blacks and whites, it was not associated with either death outcome in Hispanic patients. Further studies are needed to demonstrate whether different strategies should be followed for the management of serum potassium levels according to race/ethnicity
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