Cluster observations of trapped ions interacting with magnetosheath mirror modes

Mirror modes are among the most intense low frequency plasma wave phenomena observed in the magnetosheaths of magnetized planets. They appear as large amplitude non-propagating fluctuations in the magnetic field magnitude and plasma density. These structures are widely accepted to represent a non-linear stage of the mirror instability, dominant in plasmas with large ion beta and a significant ion temperature anisotropy <I>T</I>_&perp;/<I>T</I>_&parallel;&gt;1. It has long been recognized that the mirror instability both in the linear and non-linear stage is a kinetic process and that the behavior of resonant particles at small parallel velocities is crucial for its development and saturation. While the dynamics of the instability and the effect of trapped particles have been studied extensively in theoretical models and numerical simulations, only spurious observations of the trapped ions were published to date. In this work we used data from the Cluster spacecraft to perform the first detailed experimental study of ion velocity distribution associated with mirror mode oscillations. We show a conclusive evidence for the predicted cooling of resonant ions at small parallel velocities and heating of trapped ions at intermediate pitch angles

Local wavelet correlation: applicationto timing analysis of multi-satellite CLUSTER data

International audienceMulti-spacecraft space observations, such as those of CLUSTER, can be used to infer information about local plasma structures by exploiting the timing differences between subsequent encounters of these structures by individual satellites. We introduce a novel wavelet-based technique, the Local Wavelet Correlation (LWC), which allows one to match the corresponding signatures of large-scale structures in the data from multiple spacecraft and determine the relative time shifts between the crossings. The LWC is especially suitable for analysis of strongly non-stationary time series, where it enables one to estimate the time lags in a more robust and systematic way than ordinary cross-correlation techniques. The technique, together with its properties and some examples of its application to timing analysis of bow shock and magnetopause crossing observed by CLUSTER, are presented. We also compare the performance and reliability of the technique with classical discontinuity analysis methods. Key words. Radio science (signal processing) – Space plasma physics (discontinuities; instruments and techniques

Dunkl operators and a family of realizations of osp(1|2)

In this paper, a family of radial deformations of the realization of the Lie superalgebra osp(1|2) in the theory of Dunkl operators is obtained. This leads to a Dirac operator depending on 3 parameters. Several function theoretical aspects of this operator are studied, such as the associated measure, the related Laguerre polynomials and the related Fourier transform. For special values of the parameters, it is possible to construct the kernel of the Fourier transform explicitly, as well as the related intertwining operator.Comment: 28 pages, some small changes, accepted in Trans. Amer. Math. So

Introduction to \u3ci\u3eContent and Context of Visual Arts In the Islamic World: Papers From a Colloquium In Memory of Richard Ettinghausen\u3c/i\u3e

The edited papers presented in this memorial volume offer tribute to Richard Ettinghausen, scholar, teacher, curator and friend, a great man who affected within his own lifetime the study of Islamic art throughout the Western world. Through the high caliber of his scholarship and his discerning connoisseurship, he had a profound effect on the intellectual development of those whom he touched through his manifold activities, whether in publications, formal lectures, or an informal sharing of his knowledge. In recognition of his many achievements he received in 1976 Pour le Merite, the highest civil decoration awarded by the Federal Republic of Germany. As a teacher of Islamic art at New York University\u27s Institute of Fine Arts from 1961, where he held the Hagop Kevorkian Professorship of Islamic Art from its establishment until his death in April 1979, his training of graduate students was enhanced by his active participation in the museum world. He was active both as a curator at the Freer Gallery of Art of the Smithsonian Institution in Washington, D. C., and as a consultant to the Walters Art Gallery in Baltimore, the Virginia Museum of Fine Arts in Richmond, and the L. A. Mayer Memorial Institute of Islamic Art in Jerusalem. In his final museum post, as Consultative Chairman of the Department of Islamic Art at The Metropolitan Museum of Art from 1967 to 1979, he supervised not only the building and publication of that collection but also directed its permanent installation, thereby furthering knowledge of both the scholarly community and the general public. He also served on the Board of Trustees for The Hagop Kevorkian Fund, The Philiips Gallery, and The Textile Museum. Richard Ettinghausen was generous with his time, offering advice or criticism to colleagues, students, and friends, and was also active as a public lecturer in both the United States and Europe. He was distinguished by the wide range of his interests. Very much aware of the larger cultural context of great works of art he was also concerned with the significance of objects in daily use and their connection with the life of people in the Islamic world. He encouraged his students to enhance public appreciation of Islamic art by working with museum and gallery exhibitions and by contributing to publications and educational programs

Molecular basis of FIR-mediated c-myc transcriptional control

The far upstream element (FUSE) regulatory system promotes a peak in the concentration of c-Myc during cell cycle. First, the FBP transcriptional activator binds to the FUSE DNA element upstream of the c-myc promoter. Then, FBP recruits its specific repressor (FIR), which acts as an on/off transcriptional switch. Here we describe the molecular basis of FIR recruitment, showing that the tandem RNA recognition motifs of FIR provide a platform for independent FUSE DNA and FBP protein binding and explaining the structural basis of the reversibility of the FBP-FIR interaction. We also show that the physical coupling between FBP and FIR is modulated by a flexible linker positioned sequentially to the recruiting element. Our data explain how the FUSE system precisely regulates c-myc transcription and suggest that a small change in FBP-FIR affinity leads to a substantial effect on c-Myc concentration.MRC Grant-in-aid U11757455

The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA

Numerous RNA binding proteins are deposited onto an mRNA transcript to modulate post-transcriptional processing events ensuring proper mRNA maturation. Defining the interplay between RNA binding proteins that couple mRNA biogenesis events is crucial for understanding how gene expression is regulated. To explore how RNA binding proteins control mRNA processing, we investigated a role for the evolutionarily conserved polyadenosine RNA binding protein, Nab2, in mRNA maturation within the nucleus. This work reveals that nab2 mutant cells accumulate intron-containing pre-mRNA in vivo. We extend this analysis to identify genetic interactions between mutant alleles of nab2 and genes encoding the splicing factor, MUD2, and the RNA exosome, RRP6, with in vivo consequences of altered pre-mRNA splicing and poly(A) tail length control. As further evidence linking Nab2 proteins to splicing, an unbiased proteomic analysis of vertebrate Nab2, ZC3H14, identifies physical interactions with numerous components of the spliceosome. We validated the interaction between ZC3H14 and U2AF2/U2AF^(65). Taking all the findings into consideration, we present a model where Nab2/ZC3H14 interacts with spliceosome components to allow proper coupling of splicing with subsequent mRNA processing steps contributing to a kinetic proofreading step that allows properly processed mRNA to exit the nucleus and escape Rrp6-dependent degradation

Turbulence Heating ObserveR – satellite mission proposal

The Universe is permeated by hot, turbulent, magnetized plasmas. Turbulent plasma is a major constituent of active galactic nuclei, supernova remnants, the intergalactic and interstellar medium, the solar corona, the solar wind and the Earth’s magnetosphere, just to mention a few examples. Energy dissipation of turbulent fluctuations plays a key role in plasma heating and energization, yet we still do not understand the underlying physical mechanisms involved. THOR is a mission designed to answer the questions of how turbulent plasma is heated and particles accelerated, how the dissipated energy is partitioned and how dissipation operates in different regimes of turbulence. THOR is a single-spacecraft mission with an orbit tuned to maximize data return from regions in near-Earth space – magnetosheath, shock, foreshock and pristine solar wind – featuring different kinds of turbulence. Here we summarize the THOR proposal submitted on 15 January 2015 to the ‘Call for a Medium-size mission opportunity in ESAs Science Programme for a launch in 2025 (M4)’. THOR has been selected by European Space Agency (ESA) for the study phase