4,664 research outputs found
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The Kay Bailey Hutchison Center for Energy, Law, and Busines
Designing Institutional Infrastructure for E-Science
A new generation of information and communication infrastructures, including advanced Internet computing and Grid technologies, promises more direct and shared access to more widely distributed computing resources than was previously possible. Scientific and technological collaboration, consequently, is more and more dependent upon access to, and sharing of digital research data. Thus, the U.S. NSF Directorate committed in 2005 to a major research funding initiative, “Cyberinfrastructure Vision for 21st Century Discovery”. These investments are aimed at enhancement of computer and network technologies, and the training of researchers. Animated by much the same view, the UK e-Science Core Programme has preceded the NSF effort in funding development of an array of open standard middleware platforms, intended to support Grid enabled science and engineering research. This proceeds from the sceptical view that engineering breakthroughs alone will not be enough to achieve the outcomes envisaged. Success in realizing the potential of e-Science—through the collaborative activities supported by the "cyberinfrastructure," if it is to be achieved, will be the result of a nexus of interrelated social, legal, and technical transformations.e-science, cyberinfrastructure, information sharing, research
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Backyard Politics, National Policies: Understanding the Opportunity Costs of National Fracking Bans
Some local communities in the United States, particularly in the Northeast, are scrambling to oppose natural gas production enabled by hydraulic fracturing (or fracing, fracking, or hydrofracking) in shale formations. Local opposition to the impacts of fracking is understandable, but recent proposals for national bans ignore a key, more potent threat. Due to a mismatch between the benefits and costs of fracking, on the one hand, and the distribution of political and legal influence, on the other, the voices of those opposed to extraction may drown out the more distant voices of those suffering from the widespread future effects of coal—the primary fossil alternative to gas. Energy policy processes must recognize the opportunity costs of banning gas, including the consequences of continuing to rely on coal as our primary electricity source. The negative environmental impacts of natural gas extraction must be addressed, and our focus on gas ought not to divert attention from the need to develop more sustainable energy alternatives. However, policymakers should not adopt the myopic view advocated by some anti-fracking activists. Rather, policymakers should formulate energy policies that fully weigh the costs and benefits of alternative courses of action and consider the interests of those under-represented in the policy process.The Kay Bailey Hutchison Center for Energy, Law, and Busines
Cameron needs to convince both the member states and the EU institutions before his own side
The renegotiation of the UK’s membership has left many baffled as to what exactly Prime Minister David Cameron’s strategy really was. As David Spence argues, Cameron has faced a large and diverse number of negotiating partners in both the EU and the UK. One way of understanding what he and the many other negotiating partners hoped to achieve is by using an approach British civil servants have long been taught about negotiations: to think of the ideal, realistic and fall-back positions for the negotiation abroad and to reflect on these same three positions in terms of each of the UK’s negotiation partners, including in the ‘nested games’ at home
TOWARDS INSTITUTIONAL INFRASTRUCTURES FOR E-SCIENCE: The Scope of the Challenge
The three-fold purpose of this Report to the Joint Information Systems Committee (JISC) of the Research Councils (UK) is to: • articulate the nature and significance of the non-technological issues that will bear on the practical effectiveness of the hardware and software infrastructures that are being created to enable collaborations in e- Science; • characterise succinctly the fundamental sources of the organisational and institutional challenges that need to be addressed in regard to defining terms, rights and responsibilities of the collaborating parties, and to illustrate these by reference to the limited experience gained to date in regard to intellectual property, liability, privacy, and security and competition policy issues affecting scientific research organisations; and • propose approaches for arriving at institutional mechanisms whose establishment would generate workable, specific arrangements facilitating collaboration in e-Science; and, that also might serve to meet similar needs in other spheres such as e- Learning, e-Government, e-Commerce, e-Healthcare. In carrying out these tasks, the report examines developments in enhanced computer-mediated telecommunication networks and digital information technologies, and recent advances in technologies of collaboration. It considers the economic and legal aspects of scientific collaboration, with attention to interactions between formal contracting and 'private ordering' arrangements that rest upon research community norms. It offers definitions of e-Science, virtual laboratories, collaboratories, and develops a taxonomy of collaborative e-Science activities which is implemented to classify British e-Science pilot projects and contrast these with US collaboratory projects funded during the 1990s. The approach to facilitating inter-organizational participation in collaborative projects rests upon the development of a modular structure of contractual clauses that permit flexibility and experience-based learning.
The average magnetic field draping and consistent plasma properties of the Venus magnetotail
A new technique has been developed to determine the average structure of the Venus magnetotail (in the range from −8 Rv to −12 Rv) from the Pioneer Venus magnetometer observations. The spacecraft position with respect to the cross-tail current sheet is determined from an observed relationship between the field-draping angle and the magnitude of the field referenced to its value in the nearby magnetosheath. This allows us statistically to remove the effects of tail flapping and variability of draping for the first time and thus to map the average field configuration in the Venus tail. From this average configuration we calculate the cross-tail current density distribution and J × B forces. Continuity of the tangential electric field is utilized to determine the average variations of the X-directed velocity which is shown to vary from −250 km/s at −8 Rv to −470 km/s at −12 Rv. From the calculated J × B forces, plasma velocity, and MHD momentum equation the approximate plasma acceleration, density, and temperature in the Venus tail are determined. The derived ion density is approximately ∼0.07 p+/cm³ (0.005 O+/cm³) in the lobes and ∼0.9 p+/cm³ (0.06 O+/cm³) in the current sheet, while the derived approximate average plasma temperature for the tail is ∼6×106 K for a hydrogen plasma or ∼9×107 K for an oxygen plasma
Effect of excess iron on oxidative dehydrogenation of 1-butene over a series of zinc ferrite catalysts
The influence of excess Fe3+ in ZnFe2O4 for the catalytic oxidative dehydrogenation of 1-butene to 1, 3-butadiene was investigated to try to clarify inconsistencies in the existing literature. A series of nanoscale zinc ferrite powders were produced with increasing Fe: Zn ratios. The materials were characterized by a range of techniques, which showed the presence of α-Fe2O3 as a distinct phase with an increasing excess of Fe3+ and SEM highlighted the increased presence of surface structures on the ferrites at higher Fe: Zn ratios. Reaction testing showed α-Fe2O3to be virtually inactive for the oxidative dehydrogenation of 1-butene. Results for the ferrite catalysts showed a significant decrease in both conversion and yield with an increasing excess of Fe3+. Therefore an excess of Fe3+ has a negative effect on catalytic activity and selectivity of zinc ferrite for the oxidative dehydrogenation of 1-butene, but acts as a promoter for competing hydrogenation and combustion side reactions
Enhanced Na\u3csup\u3e+\u3c/sup\u3e/H\u3csup\u3e+\u3c/sup\u3e Exchange During Ischemia and Reperfusion Impairs Mitochondrial Bioenergetics and Myocardial Function
Inhibition of Na+/H+ exchange (NHE) during ischemia reduces cardiac injury due to reduced reverse mode Na+/Ca2+ exchange. We hypothesized that activating NHE-1 at buffer pH 8 during ischemia increases mitochondrial oxidation, Ca2+ overload, and reactive O2 species (ROS) levels and worsens functional recovery in isolated hearts and that NHE inhibition reverses these effects. Guinea pig hearts were perfused with buffer at pH 7.4 (control) or pH 8 +/- NHE inhibitor eniporide for 10 minutes before and for 10 minutes after 35- minute ischemia and then for 110 minutes with pH 7.4 buffer alone. Mitochondrial NADH and FAD, [Ca2+], and superoxide were measured by spectrophotofluorometry. NADH and FAD were more oxidized, and cardiac function was worse throughout reperfusion after pH 8 versus pH 7.4, Ca2+ overload was greater at 10-minute reperfusion, and superoxide generation was higher at 30-minute reperfusion. The pH 7.4 and eniporide groups exhibited similar mitochondrial function, and cardiac performance was most improved after pH 7.4+eniporide. Cardiac function on reperfusion after pH 8+eniporide was better than after pH 8. Percent infarction was largest after pH 8 and smallest after pH 7.4+eniporide. Activation of NHE with pH 8 buffer and the subsequent decline in redox state with greater ROS and Ca2+ loading underlie the poor functional recovery after ischemia and reperfusion
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