88 research outputs found

    Geochemical characterization of oceanic basalts using Artificial Neural Network

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    The geochemical discriminate diagrams help to distinguish the volcanics recovered from different tectonic settings but these diagrams tend to group the ocean floor basalts (OFB) under one class i.e., as mid-oceanic ridge basalts (MORB). Hence, a method is specifically needed to identify the OFB as normal (N-MORB), enriched (E-MORB) and ocean island basalts (OIB)

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised

    Humanity's Last Exam

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    Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve over 90\% accuracy on popular benchmarks like MMLU, limiting informed measurement of state-of-the-art LLM capabilities. In response, we introduce Humanity's Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be the final closed-ended academic benchmark of its kind with broad subject coverage. HLE consists of 3,000 questions across dozens of subjects, including mathematics, humanities, and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable, but cannot be quickly answered via internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a significant gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai

    Oceanography and Marine Geology in India

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    20-2

    Hot water in the cold sea environment Hydrothermal activity in the oceans

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    21-2

    A Comprehensive View of Manganese Nodules and Volcanics of the Central Indian Ocean Basin

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    The Central Indian Ocean Basin (CIOB) is the most studied basin in the Indian Ocean because of the Indian Manganese Nodules program. During the last two and half decades (and also on going), immense efforts have been made to investigate the nodule domain so as to locate the first generation nodule mine field. Over 4 million sq.km of the sea floor in the CIOB was surveyed using different samplers and echo sounders (single and multibeam). The basic requirement to identify the mine site was the abundance of the nodules (weight in kg/m2), grade of the nodule (i.e., combined percentage of Ni + Cu + Co) and the topography of the area. Various aspects related with nodules have been inspected resulting in a number of research publications, and a model derived for the growth and location of mineable ferromanganese deposits in the CIOB. Besides the ferromanganese deposits, this paper also deals with the physiographic features (seamounts, fracture zones), sediment types and on a variety of volcanics and hydrothermal materials recovered from the CIOB. It is inferred that the volcanics constitute an important part of the basin and have influenced the growth of the ferromanganese deposits. We observe that in the CIOB the presence of seamounts, types of volcanics, episodes of volcanism and altered products vis-à-vis the distribution of ferromanganese deposits are intrinsically woven and complement one another
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