88 research outputs found
1-Phenyl-6,7,8,9-hexahydro-1H,5H-cyclohepta[1′,2′:2,3]pyrido[6,5-c]pyrazol-4-amine: a new tacrine analogue
The title compound, C17H18N4, contains a pyrazolopyridine system fused with a seven-membered carbocyclic ring. The pyrazole ring is coplanar with the pyridine ring, while the phenyl ring is twisted by a dihedral angle of 14.38 (14)° with respect to the pyridine ring. The seven-membered ring displays a chair conformation. The packing is stabilized by N—H⋯N hydrogen bonds and N—H⋯π(arene) interactions
Activation of nuclear factor-κB during orthotopic liver transplantation in rats is protective and does not require kupffer cells
Glycine‐gated chloride channels in neutrophils attenuate calcium influx and superoxide production
Glycine modulates cytokine secretion, inhibits hepatic damage and improves survival in a model of endotoxemia in mice
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