Natural Connection with Totally Skew-Symmetric Torsion on Riemannian Almost Product Manifolds

On a Riemannian almost product manifold $(M,P,g)$ we consider a linear connection preserving the almost product structure $P$ and the Riemannian metric $g$ and having a totally skew-symmetric torsion. We determine the class of the manifolds $(M,P,g)$ admitting such a connection and prove that this connection is unique in terms of the covariant derivative of $P$ with respect to the Levi-Civita connection. We find a necessary and sufficient condition the curvature tensor of the considered connection to have similar properties like the ones of the K\"ahler tensor in Hermitian geometry. We pay attention to the case when the torsion of the connection is parallel. We consider this connection on a Riemannian almost product manifold $(G,P,g)$ constructed by a Lie group $G$.Comment: 14 pages, a revised edition, an example is adde

Canonical connection on a class of Riemannian almost product manifolds

The canonical connection on a Riemannian almost product manifold is an analogue to the Hermitian connection on an almost Hermitian manifold. In this paper we consider the canonical connection on a class of Riemannian almost product manifolds with non-integrable almost product structure. We construct and characterize an example by a Lie group.Comment: 19 pages, some corrections in the example; J. Geom. (2012

Renal Hemodynamics In Patients With Beta-Thalassemia Major

Introduction: Chronic anemia and hypoxia in patients with β-thalassemia major (β-ТМ) lead to disorders of renal hemodynamics. Renal blood flow and eGFR are increased. Hyperfiltration contributes to the progression of CKD.Aim: The aim of this article is to measure the glomerular filtration and to find a correlation between eGFR, ferritin levels and the age of patients with β-ТМ.Materials and Methods: The study includes 44 patients with β-ТМ aged from 7 to 57 years, with an average of 24.3±12.71 years, of whom 18 childrеn and 26 adults. Glomerular filtration is estimated by Schwartz formula for children from 1 to 17 years and MDRD for adults.Results: It was proved that the patients in the study to have a hyperfiltration (mean GFR—151.25 mL/min ±41.18880 SD) and CKD G1. A positive correlation was found between eGFR and ferritin levels and between eGFR and the age of patients with β-TM

Does COVID-19 infection affect the effectiveness of hemodialysis?

Introduction: The COVID-19 pandemic has had a lasting impact on healthcare in many Western countries. It has been proven that the infection damages the vasculature of affected patients (both microvascular and macrovascular damage). In this study, we compared the effectiveness of the dialysis procedure by examining the parameters of the Urea Reduction Ratio (URR) and Kt/V in patients before and after infection with COVID-19.Materials and Methods: The study included 50 patients with end-stage renal disease undergoing chronic hemodialysis therapy who had also experienced COVID-19 infection. Among them, 29 were men and 21 were women, with an average age of 64 years. Of the 49 patients, 22 had an arteriovenous fistula, 24 had a permanent central venous catheter for hemodialysis, and 2 had a temporary central venous catheter. All patients were examined under the same conditions before and after COVID-19 infection (equal procedure duration, identical filters, and vascular access).Results: The values of the Urea Reduction Ratio (URR) and Kt/V were measured in patients before and after experiencing COVID-19 infection. The study did not find a significant difference in the effectiveness of hemodialysis before and after COVID-19 among the cohort of examined patients.Conclusion: Although macrovascular damage has been described in the literature in cases of COVID-19 infection, no significant difference in the quality of vascular access was observed in the studied population

FLOWCYTOMETRIC STUDIES OF CELL IMMUNITY IN PATIENTS WITH URAEMIA ON PERIODIC HAEMODIALYSIS AND AFTER RENAL TRANSPLANTATION

The course of a series of kidney diseases is characterized by impaired immunity additionally altered during haemodialysis and after renal transplantation. The study covered 50 patients divided into three groups: 16 patients with chronic renal failure (CRF), 23 ones on periodic haemodialysis (PHD), and 11 after renal transplantation. Flowcytometric immunophenotyping by means of FACS-analysis using monoclonal antibodies was carried out. The investigation aimed at revealing the changes in the cell immunity, activation of surface markers and adhesion molecules in these patients. Statistically significant changes in the expression of 1С AM-1 adhesion molecules were established as followed: CD54+/ CD4+ = 24,8 ± 11,6 (in CRF) against 14,9 ±8,1 (in PHD) atp < 0,05 and CD54+/CD8+ = 17 ± 6,9 (in CRF) against 10,3 ± 4,8 (in PHD) at p < 0,05. A conclusion was drawn that immune response damage in PHD patients resulted mainly from the lowered expression of the adhesion molecules of the ICAM-1 immunoglobulin gene superfamily

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Electrical Wada for pre‐surgical memory testing: a case report

We report a case study of a surgical candidate, a 51-year-old woman with left temporal lobe epilepsy, who failed a left injection intracarotid amobarbital procedure (e.g., Wada test), scoring 0 of 8 items. This raised concerns for postoperative memory decline. However, the patient was uninterested in a neuromodulatory approach and wished to be reconsidered for surgery. A stereotactic laser amygdalohippocampotomy (SLAH) was considered, encouraging the need for an alternative test to evaluate risk of memory decline. We developed a novel approach to testing memory during stimulation of a depth electrode implanted in the hippocampus, i.e., an electric Wada. During multiple stimulation trials across a range of amplitudes, the patient scored up to 8 of 8 items, which suggested strong contralateral memory support. The surgical team proceeded with a radiofrequency ablation and a subsequent SLAH. The patient remains seizure-free at 12 months post SLAH with no evidence of verbal or visuospatial memory decline based on a post-surgical neuropsychological battery. We believe that this case study provides a proof of concept for the feasibility and possible utility of an electric version of the Wada procedure. Future studies are needed to develop an optimal paradigm and to validate this approach

A New Approach on Estimation of Solubility and n-octanol/water Partition Coefficient for Organohalogen Compounds

The aqueous solubility (logW) and n-octanol/water partition coefficient (logPOW) are important properties for pharmacology, toxicology and medicinal chemistry. Based on an understanding of the dissolution process, the frontier orbital interaction model was suggested in the present paper to describe the solvent-solute interactions of organohalogen compounds and a general three-parameter model was proposed to predict the aqueous solubility and n-octanol/water partition coefficient for the organohalogen compounds containing nonhydrogen-binding interactions. The model has satisfactory prediction accuracy. Furthermore, every item in the model has a very explicit meaning, which should be helpful to understand the structure-solubility relationship and may be provide a new view on estimation of solubility

A classification of the torsion tensors on almost contact manifolds with B-metric

The space of the torsion (0,3)-tensors of the linear connections on almost contact manifolds with B-metric is decomposed in 15 orthogonal and invariant subspaces with respect to the action of the structure group. Three known connections, preserving the structure, are characterized regarding this classification.Comment: 17 pages, exposition clarified, references adde