519 research outputs found

    The Truant Life

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    Gas Turbine Emissions Improvements by Advances in Design, Analysis, Materials, Manufacturing, and Control Technology

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    TutorialThis tutorial provides a general overview of the state of gas turbine combustion technology. Fundamental considerations for key pollutants are discussed along with techniques to control them. Since the commercial introduction of lean combustion in the early 1990s, it has become the preferred technology to minimize NOx emissions from a gas turbine, while Selective Catalytic Reduction (SCR) has remained a necessary technique to further reduce NOx emissions in some regulated areas with poor air quality. Improved designs have been enabled by more capable analysis, manufacturing techniques, and materials. All of this is leading to lower emissions engines with greater fuel flexibility and durability. Traditional diffusion flame combustion systems generate NOx between 100 and 400 ppm on natural gas, while early DLE systems started at 42 ppm and are now capable of single digit NOx

    Tumor suppressor p53 binds with high affinity to CTG-CAG trinucleotide repeats and induces topological alterations in mismatched duplexes

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    DNA binding is central to the ability of p53 to function as a tumor suppressor. In line with the remarkable functional versatility of p53, which can act on DNA as a transcription, repair, recombination, replication, and chromatin accessibility factor, the modes of p53 interaction with DNA are also versatile. One feature common to all modes of p53-DNA interaction is the extraordinary sensitivity of p53 to the topology of its target DNA. Whereas the strong impact of DNA topology has been demonstrated for p53 binding to sequence-specific sites or to DNA lesions, the possibility that DNA structure-dependent recognition may underlie p53 interaction with other types of DNA has not been addressed until now. We demonstrate for the first time that conformationally flexible CTG·CAG trinucleotide repeats comprise a novel class of p53-binding sites targeted by p53 in a DNA structure-dependent mode in vitro and in vivo. Our major finding is that p53 binds to CTG·CAG tracts by different modes depending on the conformation of DNA. Although p53 binds preferentially to hairpins formed by either CTG or CAG strands, it can also bind to linear forms of CTG·CAG tracts such as canonic B DNA or mismatched duplex. Intriguingly, by binding to a mismatched duplex p53 can induce further topological alterations in DNA, indicating that p53 may act as a DNA topology-modulating factor

    Economic Freedom and Recidivism: Evidence from US States

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    This paper provides an exploratory analysis into factors contributing to differences across states in recidivism rates. We provide the first such examination that incorporates differences in economic freedom. Using a panel data set from 1998- 2010, we find that higher levels of economic freedom within a state are associated with lower recidivism rates within that state. A one percent increase in economic freedom is associated with a 0.47 percent decrease in recidivism. The relationship is stronger and more statistically significant for labor market freedom, with a one percent increase in labor market freedom being associated with a 0.67 percent decline in recidivism

    Gas Turbine Emissions Improvements by Advances in Design, Analysis, Materials, Manufacturing, and Control Technology

    Get PDF
    TutorialThis tutorial provides a general overview of the state of gas turbine combustion technology. Fundamental considerations for key pollutants are discussed along with techniques to control them. Since the commercial introduction of lean combustion in the early 1990s, it has become the preferred technology to minimize NOx emissions from a gas turbine, while Selective Catalytic Reduction (SCR) has remained a necessary technique to further reduce NOx emissions in some regulated areas with poor air quality. Improved designs have been enabled by more capable analysis, manufacturing techniques, and materials. All of this is leading to lower emissions engines with greater fuel flexibility and durability. Traditional diffusion flame combustion systems generate NOx between 100 and 400 ppm on natural gas, while early DLE systems started at 42 ppm and are now capable of single digit NOx

    Economic Freedom Studies at the State Level: A Survey

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    This chapter synthesizes and elaborates on much of the existing research using the Economic Freedom of North America (EFNA) index. Our consensus after reading this literature is that the EFNA index, similarly to the Economic Freedom of the World (EFW) index, is largely positively related with “good” outcomes, and negatively related with “bad” ones, although there are a few exceptions. The literature using the EFNA is growing rapidly and can provide a useful guide towards future policy changes and economic outcomes

    Peanut Growing in the Gulf Coast Prairie of Texas.

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    16 p

    Management by objectives at a research development, test and evaluation activity

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    NAVMAT Instruction 5200.37 of 24 September 1973 required a Management by Objectives (MBO) program to be initiated throughout the Naval Material establishment. The Pacific Missile Range (PMR) at Point Mugu , California requested assistance from the Naval Postgraduate School in establishing their MBO program. A pilot MBO program was established at PMR to determine MBO • s feasibility in a research and development (R§D) organization. Due to time constraints, the program was limited to the implementation of short range goals and objectives. Although R§D objectives for work of an innovative nature were often difficult to define and measure, preliminary results indicate that the concept of MBO can be effectively applied to an R&D activity.http://archive.org/details/managementbyobje00blosApproved for public release; distribution is unlimited
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